Tuberculosis is a severe global health problem. There are nearly two million deaths annually from tuberculosis and one third of the world's population is believed infected with Mycobacterium tuberculosis, the bacterium responsible for this disease. In Miriam Braunstein's Lab, we are working to understand the basic biology and pathogenesis of M. tuberculosis as a step toward developing new tuberculosis control and prevention strategies. The Braunstein Lab is located in the School of Medicine at the University of North Carolina Chapel Hill (UNC) in the Department of Microbiology and Immunology. The Lab is associated with the Biological and Biomedical Sciences Program (BBSP) for graduate student training at UNC. The Braunstein Lab is also affiliated with the UNC Center for Infectious Disease, and the UNC Center for AIDS Research.