2000s

Publications from the 2000s

Transcription profile of Kaposi's sarcoma-associated herpesvirus in primary Kaposi's sarcoma lesions as determined by real-time PCR arrays.
Dittmer DP.
Cancer Res. 2003 May 1;63(9):2010-5.
PMID: 12727810

Viral latent proteins as targets for Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) induced lymphoma.
Staudt MR, Dittmer DP.
Curr Drug Targets Infect Disord. 2003 Jun;3(2):129-35. Review.
PMID: 12769790

The tumor microenvironment controls primary effusion lymphoma growth in vivo.
Staudt MR, Kanan Y, Jeong JH, Papin JF, Hines-Boykin R, Dittmer DP.
Cancer Res. 2004 Jul 15;64(14):4790-9.
PMID: 15256448

A baboon model for herpesvirus infection and pathogenesis.
Papin JF, Wolf R, Dittmer DP.
Recent Res. Devel. Virol., 6(2004)

Kaposi's sarcoma in the era of HAART-an update on mechanisms, diagnostics and treatment.
Dittmer DP, Vahrson W, Staudt M, Hilscher C, Fakhari FD.
AIDS Rev. 2005 Jan-Mar;7(1):56-61. Review.
PMID: 15875661

De novo generation of CD4 T cells against viruses present in the host during immune reconstitution.
Kalina T, Lu H, Zhao Z, Blewett E, Dittmer DP, Randolph-Habecker J, Maloney DG, Andrews RG, Kiem HP, Storek J.
Blood. 2005 Mar 15;105(6):2410-4. Epub 2004 Oct 12.
PMID: 15479725

Whole-genome transcription profiling of rhesus monkey rhadinovirus.
Dittmer DP, Gonzalez CM, Vahrson W, DeWire SM, Hines-Boykin R, Damania B.
J Virol. 2005 Jul;79(13):8637-50.
PMID: 15956606

Azidothymidine inhibits NF-kappaB and induces Epstein-Barr virus gene expression in Burkitt lymphoma.
Kurokawa M, Ghosh SK, Ramos JC, Mian AM, Toomey NL, Cabral L, Whitby D, Barber GN, Dittmer DP, Harrington WJ Jr.
Blood. 2005 Jul 1;106(1):235-40. Epub 2005 Mar 24.
PMID: 15790788

Role of Notch signal transduction in Kaposi's sarcoma-associated herpesvirus gene expression.
Chang H, Dittmer DP, Shin YC, Hong Y, Jung JU.
J Virol. 2005 Nov;79(22):14371-82. Erratum in: J Virol. 2006 Apr;80(8):4203. Chul, Shin-Young [corrected to Shin, Young C].
PMID: 16254371

Faster quantitative real-time PCR protocols may lose sensitivity and show increased variability.
Hilscher C, Vahrson W, Dittmer DP.
Nucleic Acids Res. 2005 Nov 27;33(21):e182.
PMID: 16314296

Methylene blue photoinactivation abolishes West Nile virus infectivity in vivo.
Papin JF, Floyd RA, Dittmer DP.
Antiviral Res. 2005 Nov;68(2):84-7. Epub 2005 Aug 9.
PMID: 16118025

Real-time quantitative PCR analysis of viral transcription.
Papin J, Vahrson W, Hines-Boykin R, Dittmer DP.
Methods Mol Biol. 2005;292:449-80.
PMID: 15507725

The latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus induces B cell hyperplasia and lymphoma.
Fakhari FD, Jeong JH, Kanan Y, Dittmer DP.
J Clin Invest. 2006 Mar;116(3):735-42. Epub 2006 Feb 23.
PMID: 16498502

Tumorigenesis: A step towards viral transformation.
Bangham J.
Nat Rev Cancer. 2006 Apr;6:254-55.

Immortalization of primary endothelial cells by the K1 protein of Kaposi's sarcoma-associated herpesvirus.
Wang L, Dittmer DP, Tomlinson CC, Fakhari FD, Damania B.
Cancer Res. 2006 Apr 1;66(7):3658-66.
PMID: 16585191

Baboon model for West Nile virus infection and vaccine evaluation.
Wolf RF, Papin JF, Hines-Boykin R, Chavez-Suarez M, White GL, Sakalian M, Dittmer DP.
Virology. 2006 Nov 10;355(1):44-51. Epub 2006 Aug 10.
PMID: 16904151

Reactivation of Kaposi's sarcoma-associated herpesvirus by natural products from Kaposi's sarcoma endemic regions.
Whitby D, Marshall VA, Bagni RK, Miley WJ, McCloud TG, Hines-Boykin R, Goedert JJ, Conde BA, Nagashima K, Mikovits J, Dittmer DP, Newman DJ.
Int J Cancer. 2007 Jan 15;120(2):321-8.
PMID: 17066452

Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: implications for therapy.
Petre CE, Sin SH, Dittmer DP.
J Virol. 2007 Feb;81(4):1912-22. Epub 2006 Nov 22.
PMID: 17121789

In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma.
Mutlu AD, Cavallin LE, Vincent L, Chiozzini C, Eroles P, Duran EM, Asgari Z, Hooper AT, La Perle KM, Hilsher C, Gao SJ, Dittmer DP, Rafii S, Mesri EA.
Cancer Cell. 2007 Mar;11(3):245-58. Erratum in: Cancer Cell. 2007 May;11(5):471.
PMID: 17349582

Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling.
Sin SH, Roy D, Wang L, Staudt MR, Fakhari FD, Patel DD, Henry D, Harrington WJ Jr, Damania BA, Dittmer DP.
Blood. 2007 Mar 1;109(5):2165-73. Epub 2006 Nov 2.
PMID: 17082322

Development of a fluorescence-based assay to screen antiviral drugs against Kaposi's sarcoma associated herpesvirus.
Nun TK, Kroll DJ, Oberlies NH, Soejarto DD, Case RJ, Piskaut P, Matainaho T, Hilscher C, Wang L, Dittmer DP, Gao SJ, Damania B.
Mol Cancer Ther. 2007 Aug;6(8):2360-70.
PMID: 17699731

Targeted therapy for Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus.
Dittmer DP, Krown SE.
Curr Opin Oncol. 2007 Sep;19(5):452-7. Review.
PMID: 17762570

AIDS related malignancies in Brazil.
Sampaio J, Brites C, Araujo I, Bacchi CE, Dittmer DP, Tanaka PY, Harrington W Jr, Netto EM.
Curr Opin Oncol. 2007 Sep;19(5):476-8. Review.
PMID: 17762574

The Rta/Orf50 transactivator proteins of the gamma-herpesviridae.
Staudt MR, Dittmer DP.
Curr Top Microbiol Immunol. 2007;312:71-100. Review.
PMID: 17089794

KSHV-associated disease in the AIDS patient.
Dittmer DP, Damania B.
Cancer Treat Res. 2007;133:129-39. Review. No abstract available.
PMID: 17672039

Liposomal daunorubicin as treatment for Kaposi's sarcoma.
Petre CE, Dittmer DP.
Int J Nanomedicine. 2007;2(3):277-88. Review.
PMID: 18019828

More on HIV-associated Kaposi's sarcoma.
Krown SE, Lee JY, Dittmer DP; AIDS Malignancy Consortium.
N Engl J Med. 2008 Jan 31;358(5):535-6; author reply 536. doi: 10.1056/NEJMc072994. No abstract available.
PMID: 18234764

EBV microRNAs in primary lymphomas and targeting of CXCL-11 by ebv-mir-BHRF1-3.
Xia T, O'Hara A, Araujo I, Barreto J, Carvalho E, Sapucaia JB, Ramos JC, Luz E, Pedroso C, Manrique M, Toomey NL, Brites C, Dittmer DP, Harrington WJ Jr.
Cancer Res. 2008 Mar 1;68(5):1436-42. doi: 10.1158/0008-5472.CAN-07-5126.
PMID: 18316607

Multiple pathways for Epstein-Barr virus episome loss from nasopharyngeal carcinoma.
Dittmer DP, Hilscher CJ, Gulley ML, Yang EV, Chen M, Glaser R.
Int J Cancer. 2008 Nov 1;123(9):2105-12. doi: 10.1002/ijc.23685.
PMID: 18688856

Burkitt lymphoma in Brazil is characterized by geographically distinct clinicopathologic features.
Queiroga EM, Gualco G, Weiss LM, Dittmer DP, Araujo I, Klumb CE, Harrington WJ Jr, Bacchi CE.
Am J Clin Pathol. 2008 Dec;130(6):946-56. doi: 10.1309/AJCP64YOHAWLUMPK.
PMID: 19019773

A review of human carcinogens--Part B: biological agents.
Bouvard V, Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, Benbrahim-Tallaa L, Guha N, Freeman C, Galichet L, Cogliano V; WHO International Agency for Research on Cancer Monograph Working Group.
Lancet Oncol. 2009 Apr;10(4):321-2. No abstract available.
PMID: 19350698

Pre-micro RNA signatures delineate stages of endothelial cell transformation in Kaposi sarcoma.
O'Hara AJ, Chugh P, Wang L, Netto EM, Luz E, Harrington WJ, Dezube BJ, Damania B, Dittmer DP.
PLoS Pathog. 2009 Apr;5(4):e1000389. doi: 10.1371/journal.ppat.1000389. Epub 2009 Apr 17.
PMID: 19381257

Human herpesvirus replication and abnormal CD8+ T cell activation and low CD4+ T cell counts in antiretroviral-suppressed HIV-infected patients.
Jacobson MA, Ditmer DP, Sinclair E, Martin JN, Deeks SG, Hunt P, Mocarski ES, Shiboski C.
PLoS One. 2009;4(4):e5277. doi: 10.1371/journal.pone.0005277. Epub 2009 Apr 17.
PMID: 19381272

Tumor suppressor microRNAs are underrepresented in primary effusion lymphoma and Kaposi sarcoma.
O'Hara AJ, Wang L, Dezube BJ, Harrington WJ Jr, Damania B, Dittmer DP.
Blood. 2009 Jun 4;113(23):5938-41. doi: 10.1182/blood-2008-09-179168. Epub 2009 Feb 27.
PMID: 19252139

Toll-like receptor signaling controls reactivation of KSHV from latency.
Gregory SM, West JA, Dillon PJ, Hilscher C, Dittmer DP, Damania B.
Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11725-30. doi: 10.1073/pnas.0905316106. Epub 2009 Jun 29.
PMID: 19564611

Disruption of LANA in rhesus rhadinovirus generates a highly lytic recombinant virus.
Wen KW, Dittmer DP, Damania B.
J Virol. 2009 Oct;83(19):9786-802. doi: 10.1128/JVI.00704-09. Epub 2009 Jul 8.
PMID: 19587030

General and target-specific RNA binding properties of Epstein-Barr virus SM posttranscriptional regulatory protein.
Han Z, Verma D, Hilscher C, Dittmer DP, Swaminathan S.
J Virol. 2009 Nov;83(22):11635-44. doi: 10.1128/JVI.01483-09. Epub 2009 Sep 2.
PMID: 19726500

Maribavir inhibits epstein-barr virus transcription in addition to viral DNA replication.
Wang FZ, Roy D, Gershburg E, Whitehurst CB, Dittmer DP, Pagano JS.
J Virol. 2009 Dec;83(23):12108-17. doi: 10.1128/JVI.01575-09. Epub 2009 Sep 16.
PMID: 19759127

Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic Acid.
Lechowicz M, Dittmer DP, Lee JY, Krown SE, Wachsman W, Aboulafia D, Dezube BJ, Ratner L, Said J, Ambinder RF.
Clin Infect Dis. 2009 Dec 15;49(12):1946-9. doi: 10.1086/648447.
PMID: 19911999

KSHV latent genes and their regulation.
Dittmer DP.
In DNA Tumor Viruses. Springer, 2009. 495-520.

Analysis and QC for real-time QPCR arrays of human microRNAs.
Dittmer DP, Chugh P, Wang D, Borowiak M, Ziemiecki R, O'Hara A.
In MicroRNA Profiling in Cancer: A Bioinformatics Perspective (2009): 47-75.