Publications

Recent lab publications since 2012

Dual inhibition of the PI3K/mTOR and MAPK pathways in Non-Hodgkin Lymphoma.
Anders P, Bhende PM, Foote M, Dittmer DP, Park SI, Damania B.
Leuk Lymphoma. 2014 Apr 25. [Epub ahead of print] No abstract available.
PMID: 24766470

Relationship of immunologic response to antiretroviral therapy with non-AIDS defining cancer incidence.
Yanik EL, Napravnik S, Cole SR, Achenbach CJ, Gopal S, Dittmer DP, Olshan AF, Kitahata MM, Mugavero MJ, Saag M, Moore RD, Mathews WC, Hunt P, Eron JJ.
AIDS. 2014 Apr 24;28(7):979-87. doi: 10.1097/QAD.0000000000000167.
PMID: 24681415

An important role for mitochondrial antiviral signaling protein in the Kaposi's sarcoma-associated herpesvirus life cycle.
West JA, Wicks M, Gregory SM, Chugh P, Jacobs SR, Zhang Z, Host KM, Dittmer DP, Damania B.
J Virol. 2014 May;88(10):5778-87. doi: 10.1128/JVI.03226-13. Epub 2014 Mar 12.
PMID: 24623417

Moving forward in HIV-associated cancer.
Gopal S, Achenbach CJ, Yanik EL, Dittmer DP, Eron JJ, Engels EA.
J Clin Oncol. 2014 Mar 20;32(9):876-80. doi: 10.1200/JCO.2013.53.1376. Epub 2014 Feb 18. No abstract available.
PMID: 24550416

Not like a wrecking ball: EBV fine-tunes MYC lymphomagenesis.
Dittmer DP.
Blood. 2014 Jan 23;123(4):460-1. doi: 10.1182/blood-2013-11-537076.
PMID: 24458272

Expression profile of microRNAs in Epstein-Barr virus-infected AGS gastric carcinoma cells.
Marquitz AR, Mathur A, Chugh PE, Dittmer DP, Raab-Traub N.
J Virol. 2014 Jan;88(2):1389-93. doi: 10.1128/JVI.02662-13. Epub 2013 Nov 13.
PMID: 24227849

The open chromatin landscape of Kaposi's sarcoma-associated herpesvirus.
Hilton IB, Simon JM, Lieb JD, Davis IJ, Damania B, Dittmer DP.
J Virol. 2013 Nov;87(21):11831-42. doi: 10.1128/JVI.01685-13. Epub 2013 Aug 28.
PMID: 23986576

Latency locus complements MicroRNA 155 deficiency in vivo.
Sin SH, Kim YB, Dittmer DP.
J Virol. 2013 Nov;87(21):11908-11. doi: 10.1128/JVI.01620-13. Epub 2013 Aug 21.
PMID: 23966392

Early experience after developing a pathology laboratory in Malawi, with emphasis on cancer diagnoses.
Gopal S, Krysiak R, Liomba NG, Horner MJ, Shores CG, Alide N, Kamiza S, Kampani C, Chimzimu F, Fedoriw Y, Dittmer DP, Hosseinipour MC, Hoffman IF.
PLoS One. 2013 Aug 7;8(8):e70361. doi: 10.1371/journal.pone.0070361. eCollection 2013.
PMID: 23950924

Systemically circulating viral and tumor-derived microRNAs in KSHV-associated malignancies.
Chugh PE, Sin SH, Ozgur S, Henry DH, Menezes P, Griffith J, Eron JJ, Damania B, Dittmer DP.
PLoS Pathog. 2013;9(7):e1003484. doi: 10.1371/journal.ppat.1003484. Epub 2013 Jul 18.
PMID: 23874201

Zidovudine-based lytic-inducing chemotherapy for Epstein-Barr virus-related lymphomas.
Bayraktar UD, Diaz LA, Ashlock B, Toomey N, Cabral L, Bayraktar S, Pereira D, Dittmer DP, Ramos JC.
Leuk Lymphoma. 2014 Apr;55(4):786-94. doi: 10.3109/10428194.2013.818142. Epub 2013 Aug 28.
PMID: 23837493

Kaposi sarcoma associated herpesvirus pathogenesis (KSHV)--an update.
Dittmer DP, Damania B.
Curr Opin Virol. 2013 Jun;3(3):238-44. doi: 10.1016/j.coviro.2013.05.012. Epub 2013 Jun 13. Review.
PMID: 23769237

Incidence and timing of cancer in HIV-infected individuals following initiation of combination antiretroviral therapy.
Yanik EL, Napravnik S, Cole SR, Achenbach CJ, Gopal S, Olshan A, Dittmer DP, Kitahata MM, Mugavero MJ, Saag M, Moore RD, Mayer K, Mathews WC, Hunt PW, Rodriguez B, Eron JJ.
Clin Infect Dis. 2013 Sep;57(5):756-64. doi: 10.1093/cid/cit369. Epub 2013 Jun 4.
PMID: 23735330

Recent cancer incidence trends in an observational clinical cohort of HIV-infected patients in the US, 2000 to 2011.
Yanik EL, Tamburro K, Eron JJ, Damania B, Napravnik S, Dittmer DP.
Infect Agent Cancer. 2013 May 24;8(1):18. doi: 10.1186/1750-9378-8-18.
PMID: 23705808

Complete genome sequence of pathogenic Guinea pig cytomegalovirus from salivary gland homogenates of infected animals.
Yang D, Tamburro K, Dittmer D, Cui X, McVoy MA, Hernandez-Alvarado N, Schleiss MR.
Genome Announc. 2013 Mar 14;1(2):e0005413. doi: 10.1128/genomeA.00054-13.
PMID: 23516193

Maribavir inhibits Epstein-Barr virus transcription through the EBV protein kinase.
Whitehurst CB, Sanders MK, Law M, Wang FZ, Xiong J, Dittmer DP, Pagano JS.
J Virol. 2013 May;87(9):5311-5. doi: 10.1128/JVI.03505-12. Epub 2013 Feb 28.
PMID: 23449792

Poisson factor models with applications to non-normalized microRNA profiling.
Lee S, Chugh PE, Shen H, Eberle R, Dittmer DP.
Bioinformatics. 2013 May 1;29(9):1105-11. doi: 10.1093/bioinformatics/btt091. Epub 2013 Feb 21.
PMID: 23428639

Tousled-like kinases modulate reactivation of gammaherpesviruses from latency.
Dillon PJ, Gregory SM, Tamburro K, Sanders MK, Johnson GL, Raab-Traub N, Dittmer DP, Damania B.
Cell Host Microbe. 2013 Feb 13;13(2):204-14. doi: 10.1016/j.chom.2012.12.005.
PMID: 23414760

mTOR inhibitors block Kaposi sarcoma growth by inhibiting essential autocrine growth factors and tumor angiogenesis.
Roy D, Sin SH, Lucas A, Venkataramanan R, Wang L, Eason A, Chavakula V, Hilton IB, Tamburro KM, Damania B, Dittmer DP.
Cancer Res. 2013 Apr 1;73(7):2235-46. doi: 10.1158/0008-5472.CAN-12-1851. Epub 2013 Feb 4.
PMID: 23382046

Viral latency locus augments B-cell response in vivo to induce chronic marginal zone enlargement, plasma cell hyperplasia, and lymphoma.
Sin SH, Dittmer DP.
Blood. 2013 Apr 11;121(15):2952-63. doi: 10.1182/blood-2012-03-415620. Epub 2013 Jan 30.
PMID: 23365457

Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins.
Chen W, Sin SH, Wen KW, Damania B, Dittmer DP.
PLoS Pathog. 2012;8(11):e1003048. doi: 10.1371/journal.ppat.1003048. Epub 2012 Nov 29.
PMID: 23209418

Vironome of Kaposi sarcoma associated herpesvirus-inflammatory cytokine syndrome in an AIDS patient reveals co-infection of human herpesvirus 8 and human herpesvirus 6A.
Tamburro KM, Yang D, Poisson J, Fedoriw Y, Roy D, Lucas A, Sin SH, Malouf N, Moylan V, Damania B, Moll S, van der Horst C, Dittmer DP.
Virology. 2012 Nov 10;433(1):220-5. doi: 10.1016/j.virol.2012.08.014. Epub 2012 Aug 24.
PMID: 22925337

Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma.
Bhatt AP, Jacobs SR, Freemerman AJ, Makowski L, Rathmell JC, Dittmer DP, Damania B.
Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11818-23. doi: 10.1073/pnas.1205995109. Epub 2012 Jun 29.
PMID: 22752304

Quantitative analysis of the bidirectional viral G-protein-coupled receptor and lytic latency-associated nuclear antigen promoter of Kaposi's sarcoma-associated herpesvirus.
Hilton IB, Dittmer DP.
J Virol. 2012 Sep;86(18):9683-95. doi: 10.1128/JVI.00881-12. Epub 2012 Jun 27.
PMID: 22740392

Potential pitfalls in microRNA profiling.
Chugh P, Dittmer DP.
Wiley Interdiscip Rev RNA. 2012 Sep-Oct;3(5):601-16. doi: 10.1002/wrna.1120. Epub 2012 May 7. Review.
PMID: 22566380

Treatment of Kaposi sarcoma-associated herpesvirus-associated cancers.
Dittmer DP, Richards KL, Damania B.
Front Microbiol. 2012 Apr 18;3:141. doi: 10.3389/fmicb.2012.00141. eCollection 2012.
PMID: 22529843

Latent Kaposi's sarcoma-associated herpesvirus infection of monocytes downregulates expression of adaptive immune response costimulatory receptors and proinflammatory cytokines.
Gregory SM, Wang L, West JA, Dittmer DP, Damania B.
J Virol. 2012 Apr;86(7):3916-23. doi: 10.1128/JVI.06437-11. Epub 2012 Jan 25.
PMID: 22278234

Rapalogs in viral cancers.
Dittmer DP, Bhatt AP, Damania B.
Expert Opin Investig Drugs. 2012 Feb;21(2):135-8. doi: 10.1517/13543784.2012.642369. Epub 2012 Jan 4.
PMID: 22214523

Cytokine homologs of human gammaherpesviruses.
Sin SH, Dittmer DP.
J Interferon Cytokine Res. 2012 Feb;32(2):53-9. doi: 10.1089/jir.2011.0083. Epub 2011 Dec 5. Review.
PMID: 22142220

Rapamycin with antiretroviral therapy in AIDS-associated Kaposi sarcoma: an AIDS Malignancy Consortium study.
Krown SE, Roy D, Lee JY, Dezube BJ, Reid EG, Venkataramanan R, Han K, Cesarman E, Dittmer DP.
J Acquir Immune Defic Syndr. 2012 Apr 15;59(5):447-54. doi: 10.1097/QAI.0b013e31823e7884.
PMID: 22067664