UNC Stroke Trials Unit: Clinical Trials and Research Studies

The UNC Stroke Center's Stroke Trials Unit is currently recruiting for several clinical trials and research studies. These include trials of acute stroke treatments as well as trials studying stroke prevention. Please call Anne Beckwith at (919) 843-8797 for more information.

The following are ongoing stroke clinical trials and studies:  

Acute Stroke Trials (0-24h):

SOCRATES: Ticagrelor (Brilentiia) vs. Aspirin in TIA or minor ischemic stroke

iDEF: Deferoxamine Mesylate in intracerebral hemorrhage  

BASE: biomarker blood test in acute ischemic stroke 

Sub-Acute Stroke Trials (7 days or more after stroke): 

MILESTONE: Dalfampridine (Ampyra) for treatment of stable walking deficits post ischemic stroke

Navigate-ESUS: Rivaroxaban vs. Aspirin in recent Embolic Stroke of Undetermined Source (ESUS)

Investigator Initiated Stroke Research Studies:

DEPRESSION: Depression screening in UNC patients with TIA, acute ischemic stroke, intracerebral hemorrhage and subarachnoid hemorrhage

PREMIERS: Intensive periodontal treatment in patients with TIA and ischemic stroke 

GENEDCSS: genetic study to evaluate collateral status in acute ischemic stroke

Traumatic Brain Injury:

Vigilant: Evaluation of biomarkers after mild traumatic brain injury

Stroke Recovery Research Studies Through the Department of Physical Therapy:

This website is to help patients, physicians and students in finding more information regarding Stroke and Stroke Care. The data provided on this website is only for informational use and is not an alternative to medical examination nor is this site intended to provide medical advice. If you are in search of medical advice, we strongly suggest you contact your physician to develop a personalized care plan.