Neuroscience News

Matthew Judson, PhD, Publishes in the Journal of Neuroscience

Matthew Judson, PhD, Publishes in the Journal of Neuroscience

Microcephaly is a hallmark of Angelman syndrome (AS), a debilitating neurodevelopmental disorder that results from loss of function of the HECT domain E3 ubiquitin ligase, UBE3A. However, until recently, the underlying causes of slowed brain growth in individuals with AS had gone unstudied, resulting in significant gaps in understanding of the pathogenesis of the disorder.

Matthew Judson, PhD, Publishes in the Journal of Neuroscience - Read More…

Spencer Smith Awarded UNC's 2017 Philip & Ruth Hettleman Prize for Artistic & Scholarly Achievement

Spencer Smith Awarded UNC's 2017 Philip & Ruth Hettleman Prize for Artistic & Scholarly Achievement

Spencer Smith, PhD, was awarded the highly prestigious 2017 Philip and Ruth Hettleman Prize for Artistic and Scholarly Achievement. Established by Philip Hettleman in 1986, the award recognizes four highly promising faculty members at Carolina. The recipients will be given a $5,000 stipend and will receive recognition at the UNC Faculty Council meeting.

Spencer Smith Awarded UNC's 2017 Philip & Ruth Hettleman Prize for Artistic & Scholarly Achievement - Read More…

Jiami Guo, Anton Lab Postdoctoral Scholar, Publishes in Developmental Cell

Jiami Guo, Anton Lab Postdoctoral Scholar, Publishes in Developmental Cell

An antenna-like structure on cells, once considered a useless vestige, appears to be important for proper brain development in mammals and when impaired can cause defects in the brain’s wiring similar to what’s seen in autism, schizophrenia, and other neuropsychiatric disorders. In lab experiments, UNC School of Medicine scientists prevented these wiring defects by restoring signaling though these antenna-like structures called primary cilia. The study was published on August 7, 2017 in Developmental Cell.

Jiami Guo, Anton Lab Postdoctoral Scholar, Publishes in Developmental Cell - Read More…

Spencer Smith to Lead $10-Million Project to Build Brain-Imaging Technology

Spencer Smith to Lead $10-Million Project to Build Brain-Imaging Technology

The five-year NSF project led by UNC Neuroscience Center research, Spencer Smith, will develop new imaging systems and technology to explore the brain like never before.

Spencer Smith to Lead $10-Million Project to Build Brain-Imaging Technology - Read More…

ALS: New Clues to the Cause and How Future Drugs Might Reverse Disease

ALS: New Clues to the Cause and How Future Drugs Might Reverse Disease

The Cohen Lab and NC State researchers team up to reverse TDP-43 protein aggregation, a hallmark of degenerative diseases.

ALS: New Clues to the Cause and How Future Drugs Might Reverse Disease - Read More…

Hiroyuki Kato Publishes in Neuron

Hiroyuki Kato Publishes in Neuron

In the study published July 6th in the journal Neuron titled, "Network-level Control of Frequency Tuning in Auditory Complex", Kato et al. found a neuronal network basis for how our brain precisely represents the external world.

Hiroyuki Kato Publishes in Neuron - Read More…

Anne Marion Taylor Recieves American Heart Association Grant

Anne Marion Taylor Recieves American Heart Association Grant

Anne Marion Taylor’s lab receives an American Heart Association grant to further their research investigating how axon damage causes synaptic remodeling following stroke

Anne Marion Taylor Recieves American Heart Association Grant - Read More…

Joseph Piven Publishes in Science Translational Medicine on Early Detection of Autism

Joseph Piven Publishes in Science Translational Medicine on Early Detection of Autism

"In a new study, Emerson et al. show that brain function in infancy can be used to accurately predict which high-risk infants will later receive an autism diagnosis...These findings must be replicated, but they represent an important step toward the early identification of individuals with autism before its characteristic symptoms develop." (http://stm.sciencemag.org/content/9/393/eaag2882)

Joseph Piven Publishes in Science Translational Medicine on Early Detection of Autism - Read More…

Timothy Gershon, MD, PhD Continues to Seek Strategy for Starving Brain Tumors

Timothy Gershon, MD, PhD Continues to Seek Strategy for Starving Brain Tumors

In the journal Cancer Research, UNC Lineberger researchers led by Neuroscience Center member Timothy R. Gershon, MD, PhD, report in the latest in a series of attempts to shut down the energy production machinery in medulloblastoma, the most common malignant brain tumor in children. The findings may help researchers identify a suitable therapeutic target within the sugar metabolism pathway, and provide clues to a scientific mystery surrounding the confounding way that some cancer cells get energy from sugar.

Timothy Gershon, MD, PhD Continues to Seek Strategy for Starving Brain Tumors - Read More…

Brotherly Love, No Matter What

Brotherly Love, No Matter What

UNC undergraduate Austin Ludwig works at the Carolina Institute for Developmental Disabilities to play a role in autism research he hopes will help millions of people, perhaps even his younger brother.

Brotherly Love, No Matter What - Read More…

Researchers Find Molecular Trigger for Brain Inflammation

Researchers Find Molecular Trigger for Brain Inflammation

UNC School of Medicine research findings could lead to new drug targets for treating multiple sclerosis and other neurodegenerative diseases, including Alzheimer’s disease.

Researchers Find Molecular Trigger for Brain Inflammation - Read More…

UNC Neurocience Labs Awarded Emerging Challenges in Biomedical Research Grants

UNC Neurocience Labs Awarded Emerging Challenges in Biomedical Research Grants

The UNC School of Medicine and NC TraCS announced that three labs were selected for $50,000 pilot grants to further Alzheimer’s Disease research being conducted at UNC.

UNC Neurocience Labs Awarded Emerging Challenges in Biomedical Research Grants - Read More…

UNC researchers link orphan receptor to opioid-induced itching

UNC researchers link orphan receptor to opioid-induced itching

With a more accurate understanding of the characteristics and function of the receptor MRGRPX2, University of North Carolina School of Medicine researchers were also able to create chemical probe that will allow them study the receptor more precisely.

UNC researchers link orphan receptor to opioid-induced itching - Read More…

WUNC Interviews Piven on Innovative Autism Research

WUNC Interviews Piven on Innovative Autism Research

On March 23, 2017 Joseph Piven, MD, director of the Carolina Institute for Developmental Disabilities, gave an interview on his new study showing it is possible to use MRI scans to predict whether babies with autistic siblings will also develop autism.

WUNC Interviews Piven on Innovative Autism Research - Read More…

Garret Stuber Receives over $2 Million Dollars to Contine Upstream Neural Circuit Research

Garret Stuber Receives over $2 Million Dollars to Contine Upstream Neural Circuit Research

Congratulations to Garret Stuber, PhD, on receiving more than $2 million dollars to continue his NIH-funded research studying upstream neural circuits that interface with VTA dopamine neurons to encode rewards and predictive cues.

Garret Stuber Receives over $2 Million Dollars to Contine Upstream Neural Circuit Research - Read More…

Stuber Lab Publishes in Nature

Stuber Lab Publishes in Nature

James Otis & colleagues publish paper entitled, Prefrontal cortex output circuits guide reward seeking through divergent cue encoding, in Nature this week.

Stuber Lab Publishes in Nature - Read More…

Researchers use MRIs to Predict Which High-Risk Babies will Develop Autism as Toddlers

Researchers use MRIs to Predict Which High-Risk Babies will Develop Autism as Toddlers

This first-of-its-kind study used MRIs to image the brains of infants, and then researchers used brain measurements and a computer algorithm to accurately predict autism before symptoms set in.

Researchers use MRIs to Predict Which High-Risk Babies will Develop Autism as Toddlers - Read More…

UNC Neuroscience Center Researcher to Headline Upcoming Science Café

UNC Neuroscience Center Researcher to Headline Upcoming Science Café

Flavio Frohlich, PhD, will be the featured scientist at next week’s Science Café at the N.C. Museum of Natural Sciences in downtown Raleigh.

UNC Neuroscience Center Researcher to Headline Upcoming Science Café - Read More…

UNC Receives $2.5-Million Grant to Explore New Therapy for Anhedonia

UNC Receives $2.5-Million Grant to Explore New Therapy for Anhedonia

As part of NIMH’s Experimental Therapeutics Initiative and led by Gabriel Dichter, PhD, researchers will use neuroimaging to evaluate a new treatment for decreased motivation and pleasure, symptoms that are common to many psychiatric disorders.

UNC Receives $2.5-Million Grant to Explore New Therapy for Anhedonia - Read More…

Stuber Lab Publishes in Nature Neuroscience

Stuber Lab Publishes in Nature Neuroscience

Garret Stuber, PhD, and his lab show that a molecularly defined subset of neurons in the anterior hypothalamus preferentially encode socially rewarding stimuli. These neurons project to and regulate the activity in midbrain dopamine neurons to enhance social motivation.

Stuber Lab Publishes in Nature Neuroscience - Read More…

Roth Lab Featured on Cover of Cell

Roth Lab Featured on Cover of Cell

Bryan Roth, PhD, and his lab report the first crystal structure of LSD bound to one of its molecular targets, the serotonin 5-HT2B receptor.

Roth Lab Featured on Cover of Cell - Read More…

17th Perl-UNC Neuroscience Prize Recipient Announced

17th Perl-UNC Neuroscience Prize Recipient Announced

The UNC School of Medicine has awarded the 17th Perl-UNC Neuroscience Prize to David Anderson, PhD, the Seymour BenzerDavid Anderson, PhD Professor of Biology at the California Institute of Technology for “his discovery of neural circuit mechanisms controlling emotional behaviors.”

17th Perl-UNC Neuroscience Prize Recipient Announced - Read More…

Smith Lab Publishes in Nature Neuroscience

Smith Lab Publishes in Nature Neuroscience

Smith Lab publishes in Nature Neuroscience, "Stream-dependent development of higher visual cortical areas".

Smith Lab Publishes in Nature Neuroscience - Read More…

Simultaneous PET/MR Grant Awarded to CIDD Faculty

Simultaneous PET/MR Grant Awarded to CIDD Faculty

Dr. Gabriel Dichter, a Carolina Institute for Developmental Disabilities (CIDD) Investigator, was recently awarded a grant from the National Institute of Mental Health to evaluate dopaminergic functioning during reward processing in individuals with autism spectrum disorder.

Simultaneous PET/MR Grant Awarded to CIDD Faculty - Read More…

Celebrity Poker Tournament in Charlotte will support UNC Angelman syndrome research

On Saturday December 10, 2016, Harvey’s Aces Celebrity Poker Tournament will be held at the Charlotte Museum of History. Proceeds will be donated to the Angelman Syndrome Foundation Clinic at Chapel Hill and the Harvey Baseball Foundation, two non-profit organizations that former professional baseball player Bryan Harvey helped create.

Celebrity Poker Tournament in Charlotte will support UNC Angelman syndrome research - Read More…