UNC Scientists Take a Big Step toward Building a Better Opioid

In a paper published in Cell, UNC School of Medicine researchers led by Bryan Roth, MD, PhD, show how to activate only one kind of brain receptor vital for pain relief. This receptor is not involved in addiction or respiratory depression that leads to death – the most severe side effects of opioid use.

UNC Scientists Take a Big Step toward Building a Better Opioid click to enlarge This is an illustration of the active state kappa opioid receptor bound to a morphine derivative (purple). (Credit: Che and Wacker, Roth Lab)

To read the full UNC School of Medicine Press Release, click here.

To read the article in Cell, click here.

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