Brain Tumor Clinical Trials

For years and years, scientists have been searching for cures and vaccines for all kinds of ailments plaguing mankind, from the common cold to cancer. There have been some successes and breakthrough discoveries, but brain tumors continue to haunt us. Brain tumor is a complex and multi-faceted disease with unknown etiology. In order to find a cure, we need to uncover the secrets to its inception, its structure, its nature, in order to create a vehicle to kill the disease -- that vehicle being either a drug or an instrument. Until we find a cure, we are dedicated to finding the best possible treatment to help you live a long and fulfilling life.

About 20,000 people are diagnosed with primary brain cancer and another 100,000 people are diagnosed with metastatic brain cancer every year in the United States. It accounts for 1.49% of all malignant tumors, but death from brain tumors account for 2.4% of cancer deaths.

Clinical trials are research studies that test new cancer drugs, diagnostic procedures and therapies on humans. A clinical trial is one of the final stages of a long and careful cancer research process. It is going to translate the promising findings from the basic research into benefits for our patients. Studies are conducted with brain cancer patients, in controlled environments and under the ethical and regulatory oversight of the Institutional Review Boards. If you are interested in participating in a clinical trial here at UNC Lineberger Comprehensive Cancer Center, please visit our Clinical Research website (link listed below).

UNC Neuro-Oncology Program also belongs to three brain tumor research consortia: Brain Tumor Trials Collaborative (BTTC), the Alliance (Alliance for Clinical Trials in Oncology), and CERN (Collaborative Ependymoma Research Network). The consortia consist of prestigious and well-respected cancer centers across the country working together and sharing their findings for a common goal: to advance treatment for patients who suffer from brain cancers.


Matthew G. Ewend, MD