Faculty


			David A. Grimes, MD Clinical Professor of Obstetrics and Gynecology. Fellow, Cecil G. Sheps Center for Health Services Research University of North Carolina. Division of Women's Primary Healthcare. Phone: (919) 544-7040 Fax: (919) 544-7261 E-Mail: dgrimes@fhi.org Mailing Address: PO Box 13950 Research Triangle Park, NC 27709 Education • Harvard University, 1969, B.A. cum laude, 1965-1969 • University of North Carolina, MD, 1969-1973 Military Service • 1975-1977 Surgeon (04) • 1979-1980 Surgeon (04) • 1981-1986 Senior Surgeon (05) • U.S. Public Health Service • Centers for Disease Control Residency University of North Carolina at Chapel Hill Obstetrics & Gynecology, 1973-5 & 1977-9 Recent Honors • Irvin Cushner Memorial Lecturer, American - College of Obstetricians and Gynecologists, 2001 • Resident Advocate Award, Department of - Obstetrics and Gynecology, University of - North Carolina School of Medicine, 2001 • Henderson Lecturer, University of Toronto, 2002 • Robert C. Cefalo Distinguished Professor Award, - University of North Carolina School of Medicine, 2002 • Michael S. Burnhill Memorial Lecturer, Planned - Parenthood Federation of America, 2002 • Sir John Dewhurst, M.D., Lectureship, North - American Society for Pediatric and Adolescent - Gynecology, 2003 • Martin L. Stone, M.D. Lecturer, Stony Brook - University Health Sciences Center, 2003 • Pouru Bhiwandiwala Leadership Award, Ipas, 2004Robert C. • Knapp, M.D. Lecturer, Brigham and Women’s Hospital, 2004 • A. Cullen Richardson Memorial Lecturer, ACOG District IV, • 2004 • Leo J. Dunn, M.D. Lecturer, Medical College of Virginia, • 2004 • Sam Seeds Visiting Professor, University of Cincinnati • Medical Center, 2005 • Lifetime Achievement Award, Society of Family Planning, • 2005 • A. Marsh Poulson, Jr., M.D. Lectureship, University of • Utah, 2006 • John Atkinson Ferrell 10th Annual Lectureship and Prize, • University of North Carolina School of Medicine, 2006 Current Positions • Vice President of Biomedical Affairs, - Family Health International Government Positions • Epidemic Intelligence Service Officer, - Centers for Disease Control, 1975-1977 • Assistant Chief, Abortion Surveillance Branch, - Centers for Disease Control, 1979-1982 • Chief, Abortion Surveillance Branch, - Centers for Disease Control, 1982-1983 • Medical Epidemiologist, Pregnancy Epidemiology - Branch, Centers for Disease Control, 1983-1984 • Clinical Research Investigator, Division of Sexually - Transmitted Diseases, Centers for Disease Control, - 1984-1986 Most Recent International Positions • Member, International Committee - for Research in Reproduction, 1993-1996 • Chair, Steering Committee, Task Force - on Post-ovulatory Methods for Fertility Regulation, - World Health Organization, 1994-1997 • Course Co-Director, Reproductive Epidemiology, - India, 1999 • Course Director, Reproductive Epidemiology, - Egypt, 2002 Board Certification • American Board of Obstetrics and Gynecology, 1981 • Recertified, 1991 • American Board of Preventive Medicine, 1986 Professional Organizations • American Gynecological and Obstetrical Society • Society for Gynecologic Investigation • American College of Obstetricians and Gynecologists • American College of Preventive Medicine • American Society for Reproductive Medicine • South Atlantic Association of Obstetricians and • Gynecologists • American Public Health Association • Association of Reproductive Health Professionals • Associate, The Alan Guttmacher Institute • Robert A. Ross Obstetrical and Gynecological Society • National Abortion Federation • Washington State Obstetrical Association (Hon.) • San Francisco Gynecological Society • Chicago Gynecological Society (Hon.) • Pacific Northwest Obstetrical and Gynecological • Association (Hon.) Clinical Interests • Contraception • Reproductive epidemiology Recent Publications Gallo MF, Grimes DA, Schulz KF: Skin patch and vaginal ring versus combined oral contraceptives for contraception (Cochrane Review). In: The Cochrane Library, Issue 1, 2003. Oxford: Update Software Cates W Jr, Grimes DA, Schulz KF: The public health impact of legal abortion: 30 years later. Perspect Sex Reprod Health 2003;35:25-28 Fraser AB, Grimes DA: The effect of lactation on maternal body weight: a systematic review. Obstet Gynecol Surv 2003;58:265-269 Gallo MF, Grimes DA, Schulz KF, Helmerhorst FM: Combination contraceptives: effects on weight (Cochrane Review). In: The Cochrane Library, Issue 2, 2003. Oxford: Update Software; reprinted in Gallo MF, Grimes DA, Schulz KF, Helmerhorst FM: Combination estrogen-progestin contraceptives and body weight: systematic review of randomized controlled trials. Obstet Gynecol 2004; 103:359-373 Truitt ST, Fraser AB, Grimes DA, Gallo MF, Schulz KF: Combined hormonal versus nonhormonal versus progestin-only contraception in lactation (Cochrane Review). In: The Cochrane Library, Issue 2, 2003. Oxford: Update Software; reprinted in Truitt ST, Fraser AB, Grimes DA, Gallo MF, Schulz KF: Hormonal contraception during lactation: systematic review of randomized controlled trials. Contraception 2003;68:233-238 Gallo MF, Grimes DA, Schulz KF: Non-latex versus latex male condoms for contraception (Cochrane Review). In: The Cochrane Library, Issue 2, 2003. Oxford: Update Software; Reprinted in Contraception 2004;68:319-26 Grimes DA: Medical misspellings. Obstet Gynecol 2003;101:843-845 Hubacher D, Grimes D, Lara-Ricalde R, de la Jara J, Garcia-Luna G: The limited clinical usefulness of taking a history in the evaluation of women with tubal factor infertility. Fertil Steril 2004;81:6-10; 18 Grimes DA: Unsafe abortion: the silent scourge. Br Med Bull 2003;67:99-113 Grimes DA, Smith MS, Witham AD: Mifepristone and misoprostol versus dilation and evacuation for midtrimester abortion: a pilot randomized controlled trial. BJOG 2004;111:148-53 Grossman D, Ellertson C, Grimes DA, Walker D: Routine follow-up visits after first-trimester induced abortion. Obstet Gynecol 2004;103:738-745 Grimes DA, Creinin MD: Induced abortion: an overview for internists. Ann Intern Med 2004;140:620-626 Grimes D, Gallo M, Grigorieva V, Nanda K, Schulz K: Steroid hormones for contraception in men (Cochrane Review). In: The Cochrane Library, Issue 3, 2004. Chichester, UK: John Wiley & sons, Ltd. Reprinted in Contraception 2005;71:89-94 Arowojolu AO, Gallo MF, Grimes DA, Garner SE: Combined oral contraceptive pills for treatment of acne (Cochrane Review). In: The Cochrane Library, Issue 3, 2004. Chichester, UK: John Wiley & Sons, Ltd. Grimes DA: Emergency contraception: Politics trumps science at the U.S. Food and Drug Administration. Obstet Gynecol 2004;104:220-1 Grimes DA: When to deliver the stunted fetus? Lancet 2004;364:483-4 Grimes DA, Gallo M, Grigorieva V, Nanda K, Schulz K: Fertility awareness-based methods for contraception. The Cochrane Database of Systematic Reviews 2004, Issue 4. Art. No.: CD004860.pub2. DOI:10.1002/14651858.pub2.; duplicate published in Contraception 2005;72:85-90 Hwang AC, Grimes DA, Shields W: Universal insurance coverage for contraceptives: a public health imperative. Contraception 2004;70:357-8 Gallo M, Grimes D, Nanda K, Schulz K: 20 mcg versus >20 mcg estrogen combined oral contraceptives for contraception. Cochrane Database Syst Rev. 2005 Apr 18:2:CD003989. Reprinted in Contraception 2005;71:162-169 Grimes DA: Risks of mifepristone abortion in context. Contraception 2005;71:161 Rogovskaya S, Rivera R, Grimes DA, Chen P-L, Pierre-Louis B, Prilepskaya V, Kulakov V: Effect of a levonorgestrel intrauterine system on women with type 1 diabetes: a randomized trial. Obstet Gynecol 2005;105:811-5 Schulz KF, Grimes DA: Sample size calculations in randomised trials: mandatory and mystical. Lancet 2005;365:1348-53 Grimes DA, Schulz KF: Compared to what? Finding controls for case-control studies. Lancet 2005;365:1429-33; reprinted in Z Arztl Fortbild Qualitatssich 2006;100:209-15 Grimes DA, Schulz KF: Refining clinical diagnosis with likelihood ratios. Lancet 2005;365:1500-5 Schulz KF, Grimes DA: Multiplicity in randomised trials. I. Endpoints and treatments. Lancet 2005;365:1591-95 Grimes DA, Schulz KF: Surrogate end points in clinical research: hazardous to your health. Obstet Gynecol 2005;105:1114-8 Schulz KF, Grimes DA: Multiplicity in randomised trials. II. Subgroup and interim analyses. Lancet 2005;365:1657-61 Grimes DA, Shields W: Family planning for obese women: challenges and opportunities. Contraception 2005;72:1-4 Grimes DA, Hubacher D, Nanda K, Schulz KF, Moher D, Altman DG: The Good Clinical Practice guideline: a bronze standard for clinical research. Lancet 2005;366:172-74 Edelman A, Gallo M, Jensen J, Nichols M, Schulz K, Grimes D: Continuous or extended cycle vs. cyclic use of combined oral contraceptives for contraception. Cochrane Database Syst Rev 2005 Jul 20;3:CD004695; reprinted in Hum Reprod 2006;21:573-8 Gallo M, Grimes D, Schulz K, d’Arcangues C, Lopez L. Combination injectable contraceptives for contraception. Cochrane Database Syst Rev 2005 Jul 20;3:CD004568 Grimes DA, Schulz KF: Clinical research in obstetrics and gynecology. More tips for busy clinicians. Obstet Gynecol Surv 2005;60:s53-s69 Lopez L, Grimes DA, Schulz KF: Non-hormonal drugs for contraception in men: A systematic review. Obstet Gynecol Surv 2005;60:746-52 Grimes DA, Lopez L, Raymond E, Halpern V, Nanda K, Schulz K: Spermicide used alone for contraception. Cochrane Database Syst Rev 2005;Oct 19;4:CD 005218 Helmerhorst F, Van Vliet H, Gornas T, Finken M, Grimes D: Intra-uterine insemination versus timed intercourse for cervical hostility in subfertile couples. Cochrane Database Syst Rev 2005 Oct 19;4:CD002809; reprinted in Obstet Gynecol Surv 2006;61:402-14 Grimes DA: Estimation of pregnancy-related mortality risk by pregnancy outcome, United States, 1991-1999. Am J Obstet Gynecol 2006;194:92-4 Halpern V, Gallo MF, Grimes DA, Lopez L. Strategies to improve compliance and acceptability of hormonal methods of contraception. Cochrane Database Syst Rev 2006;CD004317.