Chasing Pac-Man

Two UNC researchers design a biological test to individualize chemotherapy.

Chasing Pac-Man click to enlarge Photo by Mary Lide Parker

When gynecologic oncologist Paola Gehrig makes a treatment plan, she has little to go by to make sure her patient gets the best chemotherapy dose with the least amount of toxicity. For most chemotherapy drugs, the patient’s height and weight are the only factors used to determine a dose. The physician then adjusts the dose once toxicities of a drug appear: severe nausea, pain, ulcers, exhaustion, and any number of other side effects.

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endeavors is the online magazine of research and creative activity at UNC-Chapel Hill. endeavors (ISSN 1933-4338) is published by the Office of the Vice Chancellor for Researchat the University of North Carolina at Chapel Hill.

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