Ongoing Departmental Studies
GYN | "LIFE" study for fecal incontinence
STUDY BRIEF | The LIFE study is a trial for women experiencing symptoms for Fecal Incontinence (FI). This study is evaluating the use of the investigational LivSure vaginal insert for the control of FI. The insert is non-surgical and does not contain drugs or hormones. It resides in a similar position as a diaphragm or tampon and can be removed by the patient at any time. While in the vagina, the device supports the rectum in a way that may control bowel leakage.
GYN | A Necessary Multi-Parametric Evaluation of Vulvodynia
STUDY BRIEF | To develop novel tools and classification algorithms to identify the relative contribution of multiple pain mechanisms in individual patients to enhance diagnosis of vulvodynia and choice of tailored, mechanistic-based treatments.
GYN | Metformin for the Treatment of Endometrial Hyperplasia
STUDY BRIEF | Trial to assess the impact of metformin for the treatment of simple or complex endometrial hyperplasia without atypia. Metformin may offer an alternative agent for treatment of endometrial hyperplasia without causing significant side effects common to progesterone-based treatment.
GYN | Peripheral and Central Mechanisms of Vulvar Vestibulitis Syndrome (VVS)
STUDY BRIEF | To explore the relative contribution of the mucosal and muscle pain sensitivity to clinical pain report among women with vestibulodynia.
GYN | VAULT study for pelvic organ prolapse
STUDY BRIEF | The purpose of this research study is to learn about the effectiveness of 2 surgical techniques for treatment of uterovaginal prolapse: Laparoscopic/ robotic-assisted sacral hysteropexy and Vaginal Uphold Hysteropexy will be compared. Both procedures leave the uterus in place and use mesh to support the uterus and vagina. The cure rates, complications, and improvement of symptoms after these two procedures will be compared.
Mood, Mother and Infant Study
You are invited to help UNC researchers understand how breastfeeding builds bonds between mothers and babies.
OB | Time to Conceive
STUDY BRIEF | Time to Conceive is a research study that hopes to find a way to accurately measure a woman’s fertility. Women between 30 and 44 years of age who are trying to become pregnant or about to start trying are eligible to participate in the study. Women are not eligible to participate if they or their partner have a history of infertility or fertility treatment.
WOMENS HEALTH | Physical activity and health lifestyle for cancer survivors and daughters
STUDY BRIEF | Are you a survivor of Breast, Endometrial or Colorectal Cancer? If yes, we're looking for you! UNC Researchers in the Obstetrics and Gynecology Department are currently recruiting participants to attend a 90 minute focus group to determine the delivery, preferences and preferred components of a physical activity and healthy lifestyle intervention for cancer survivors and special populations.
