Alexandra Arreola-Vargas

 

Student:
Alexandra Arreola-Vargas

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Undergraduate Institution: UC-Davis
Email: aarreola@email.unc.edu
Department: Genetics and Molecular Biology
PI: Kim Rathmell
Research Summary: The focus of my research is to elucidate what genes are deregulated as a result of loss or mutation of the von Hippel-Lindau tumor suppressor gene. This is done with the aim of understanding what early genetic events following VHL mutation/loss may be responsible for renal cell carcinoma tumorigenesis. To that avail I have also generated a sphere-assay using primary neonatal epithelial kidney cells that will be used to characterize at the cell and molecular level, what cells are more prone to tumorigenic events.