Identification of Chemical-Exposure Signatures in Renal Cell Carcinomas

 

Trainee:

Michelle DeSimone

DeSimone

Research Mentor:

Dr. David Threadgill, PhD

Threadgill

Clinical Co-Mentor;

Dr. Kimryn Rathmell, MD, PhD

rathmell
Project Description:

Michelle DeSimone seeks to identify molecular biomarkers of trichloroethylene exposure in renal cell carcinomas by examining genetic mutation signatures in tumor tissues from human populations, and thereby develop preventative measures and therapeutic strategies for the treatment of chemical-exposure induced cancers.