Education and Training:
Purdue University, 1967
Scripps Clinic and Research Foundation 1972
University of Madrid, Spain 1977
National Institute of Neurological and Communicative Disorders and Stroke, NIH, 1978-1981 (under Dr. Carleton Gajdusek)
National Eye Institute, NIH, 1982-1986 (under Dr. Joram Piatigorsky)
Trabecular meshwork genes and Glaucoma Gene Therapy
My laboratory is interested in developing Gene Therapy protocols for the treatment of Glaucoma, a disease that is the most important cause of non-remedial blindness in the United States. Our research seeks to understand the mechanisms that control aqueous humor outflow resistance at the molecular level. To accomplish this goal, we are following two interrelated lines of investigation: identifying genes that are affected by insults known to induce glaucoma and developing effective gene delivery to glaucoma related eye tissues.