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UNC Orthopaedics Ambulatory Care Center 101 Mason Farm Road UNC School of Medicine Chapel Hill, NC 27599-7745 Appointments: 919.962.6637
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Ronald D. Graff, PhD
 | Research Assistant Professor of Orthopaedics | | Education | - BS: University of Waterloo, Ontario, Canada
- PhD (combined program in toxicology): Rutgers, The State University of New Jersey, and University of Medicine and Dentistry of New Jersey
| | Honors, Awards, and Recognitions | - Independent Investigator Award, Arthritis Foundation
- National Research Service Award
| | Research Interests | - Our lab studies cartilage biology and osteoarthritis with chondron cultures. A chondron is a chondrocyte with its surrounding pericellular matrix. Chondrons were first isolated from articular cartilage by Tony Poole using homogenization (mechanically isolated chondrons) see references below. In our lab, chondrons are isolated using the enzymes, dispase and collagenase (enzymatically isolated) see references below. Chondrons produce more extracellular matrix than chondrocytes isolated without their pericellular matrix.
| | Academic Appointments | | 1992-1995 | Research Assistant; Neurotoxicology Laboratories, School of Pharmacy, Rutgers University | | 1995-1998 | Postdoctoral Fellow; Department of Biochemistry, UNC School of Medicine | | 1998-2003 | Postdoctoral Fellow; Thurston Arthritis Research Center (TARC), UNC School of Medicine | | 2003-present | Research Assistant Professor; TARC and Department of Orthopaedics (joint appointment), UNC School of Medicine | | | Selected Publications | | |
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