DPLM Faculty Profiles — Dr. Qian

Dr. Qian

Li Qian, PhD

Assistant Professor

Office: 919-962-0340

Email: li_qian@med.unc.edu

Lab web site: http://uncliqian.web.unc.edu/


Qian Lab Figure 1Our laboratory is interested in developing innovative approaches to regenerate or repair an injured heart. Our goal is to understand the molecular basis of cardiomyocyte specification and maturation and apply this knowledge to improve efficiency and clinical applicability of cellular reprogramming in heart disease. To achieve these goals, we utilize in vivo modeling of cardiac disease in the mouse, including myocardial infarction (MI), cardiac hypertrophy, chronic heart failure and congenital heart disease (CHD). In addition, we take advantage of traditional mouse genetics, cell and molecular biology, biochemistry and newly developed reprogramming technologies (iPSC and iCM) to investigate the fundamental events underlying the progression of various cardiovascular diseases as well as to discover the basic mechanisms of cell reprogramming.


2012–present:  Assistant Professor

Department of Pathology and Laboratory Medicine
McAllister Heart Institute
Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill
– Ellison New Scholar in Aging

2007–2012:  Postdoctoral Fellow

Gladstone Institute for Cardiovascular Disease
University of California, San Francisco
– Roddenberry Stem Cell Biology and Medicine Scholar
– California Institute for Regenerative Medicine (CIRM) Scholar

2001–2006:  Graduate/Ph.D. Student

Department of Molecular, Cellular and Developmental Biology
University of Michigan, Ann Arbor
2003–2006: Visiting Graduate Student
Development and Aging Program
Sanford-Burnham Institute, La Jolla
University of California, San Diego

1997–2001:  Undergraduate Student

Life Science School
Fudan University, Shanghai, China
– Chun-Tsung Scholar





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