Documents for Investigators

The PGC3 Memorandum of Understanding describes the next set of aims for the PGC. We request that all participants indicate agreement with this MOU, and understand the obligations and benefits of participating. 

Accessing Individual Data

It is possible for PGC members directly to conduct analyses on the NL cluster. Obtaining access is complex, however, because of the restrictions under which many of the datasets were shared with the PGC. For example, in order to get genomic data from dbGaP, WTCCC, or the NIMH repository, an investigator must promise not to allow anyone to access the data. 

After a long series of discussions with all the stakeholders, we developed a streamlined approach. This is summarized in the “gatekeeper” document. These steps require some time, but are as minimal as we could make them. 

Please read this document carefully and follow all of the steps. 

Wellcome Trust Case Control Consortium (WTCCC)

To access these samples, please sign the WTCCC Data Access Agreement and include this in the required paperwork for data access.

dbGaP Access

Some investigators have said they have difficulty understanding what dbGaP requires in order to get access to data. Others have found the dbGaP process logical and straight-forward. If you have had difficulty, this dbGaP template for the access webpage may be helpful. 

Cross-Disorder Group Proposals

These documents include a CDG FAQ and the form by which to make a CDG proposal for approval by the CDG. These are for any analysis that proposes to use data from more than one PGC group (e.g., autism and schizophrenia). 

More information on the CDG can be found here

Proposal for Secondary Analysis

This document is a general proposal for a secondary analysis that uses data from only one group. For example, to propose a new analysis of data only for MDD.