Recent Publications

Yuan W., Leisner T. M. McFadden A.W., Wang Z., Larson M.K., Clark S., Boudignon-Proudhan C., Parise L.V. CIB1 is an endogenous inhibitor of agonist-induced integrin alphaIIbBeta3 activation. J Cell Biol, 172(2):169-75, 2006.

Leisner TM, Liu M, Jaffer ZM, Chernoff J, Parise LV. Essential role of CIB1 in regulating PAK1 activation and cell migration. J Cell Biol 170(3):465-76, 2005.

Holly S.P., Larson M.K. and Parise L.V.: The Unique N-terminus of R-Ras is Required for Rac Activation and Precise Regulation of Cell Migration. Mol Biol Cell. 16(5):2458-69, 2005.

Gentry HR, Singer AU, Betts L, Yang C, Ferrara JD, Sondek J, Parise LV. Structural and biochemical characterization of CIB1 delineates a new family of EF-hand containing proteins. J Biol Chem. 280(9):8407-15, 2005.

Murphy M.M., Zayed M.A., Evans A., Parker C.E., Ataga K.I., Telen M.J., Parise L.V. Role of Rap1 in promoting sickle red blood cell adhesion to laminin via BCAM/LU. Blood. 105(8):3322-9, 2005.

Parise, L.V., Smyth, S.S., Coller, B.S. “Platelet morphology, biochemistry, and function” Williams Hematology, 7th ed., 2005.
Brittain J.E., Han J., Ataga K.I., Orringer E.P., Parise L.V.: Mechanism of CD47-induced Alpha 4 Beta 1 Integrin Activation and Adhesion in Sickle Reticulocytes. J. Biol. Chem. 279(41):42393-402, 2004.
Zennadi R., Hines P.C., De Castro L.M., Carton J-P, Parise L.V., Telen M.J.: Epinephrine Acts via Erythroid Signaling Pathways to Activate Sickle Cell Adhesion to Endothelium via LW-alphavbeta3 Interactions. Blood, 104(12):3774-81, 2004.
Parise, L.V.: JAM-1 Regulation of Endothelial Cell Migration: Implications for Angiogenesis. Arterioscler. Thromb. Vasc. Biol., 23(12):2119-20, 2003.
Larson M.K., Parise L.V.: Platelets Made to Order. Blood, 102:3859, Capsule Commentary, 2003.
Parise L.V., Telen M.J.: Erythrocyte Adhesion in Sickle Cell Disease. Current Hematology Reports, 2(2):102-108, 2003.
Wang Z., Leisner T.M., Parise L.V.: Platelet alpha2 Beta1 Integrin Activation: Contribution of Ligand Internalization and the alpha2-Cytoplasmic Domain. Blood, 102(4):1307-1315, 2003.
Hines C.P., Zen Q., Burney S.N., Shea D., Ataga K.I., Orringer E.P., Telen M.J., Parise L.V.: Novel Epinephrine and Cyclic AMP-Mediated Activation of BCAM/Lu Dependant Sickle (SS) RBC Adhesion. Blood, 101(8):3281-3287, 2003.
Larson M.K., Chen H., Kahn M.L., Taylor A.M., Fabre J., Mortensen R.M., Conley P.B., Parise L.V.: Identification of P2Y12-dependant and -independant mechanisms of glycoprotein VI-mediated Rap1 activation in platelets. Blood, 101(4):1409-1415, 2003.
Barry W.T., Boudignon-Proudhon C., Shock D.D., McFadden A., Weiss J.M., Sondek J., Parise L.V.: Molecular Basis of CIB Binding to the Integrin AlphaIIb Cytoplasmic Domain. J. Biol. Chem., 277(32):28877-28883, 2002.

A. Bertoni, S. Tadokoro, K. Eto, N. Pampori, L.V. Parise, G.C. White, S.J. Shattil: Relationships between Rap1b, affinity modulation of integrin alphaIIbß3 and the actin cytoskeleton . J. Biol. Chem., 277(28):25715-25721, 2002.

James J. Fiordalisi, Stephen P. Holly, Ronald L. Johnson II, Leslie V. Parise, and Adrienne D. Cox: A distinct class of dominant negative Ras mutants: Cytosolic, GTP-bound Ras effector domain mutants that inhibit Ras signaling and transformation, and enhance cell adhesion. J.Biol. Chem., 277(13):10813-10823, 2002.

Parise, L.V.: "Platelet Activation: Communication with Integrin Cytoplasmic Domains" in Interactions of Blood and the Pulmonary Circulation . Eds, Weir EK, Reeve, Futura Press, NY., 2001.

Brittain, J.E., Mlinar, K.J., Anderson, C. S. Orringer, E.P., Parise, L.V.: Activation of Sickle Red Blood Cell Adhesion via Integrin-Associated Protein (IAP/CD47)-Induced Signal Transduction. J. Clin. Invest., 107(12):1555-62, 2001.

Fabre JE, Nguyen M, Athirakul K, Coggins K, McNeish JD, Austin S, Parise LV, FitzGerald GA, Coffman TM, Koller BH: Activation of the murine EP3 receptor for PGE(2) inhibits cAMP production and promotes platelet aggregation. J Clin Invest, 107(5):603-610, 2001.

Brittain, J.E., Mlinar K.J., C.S. Anderson, Orringer, E.P., Parise, L.V.: Integrin-associated protein is an adhesion receptor on sickle red blood cells for immobilized thrombospondin. Blood, 977:2159-2164, 2001.

Parise, L.V., Smyth, S.S., Coller, B.S. “Platelet morphology, biochemistry, and function” Williams Hematology, 6th ed., 2001.