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How did Gonorrhea Become a Drug-resistant Superbug?
Scientists led by Rob Nicholas, PhD, at the UNC School of Medicine show how the gonorrhea bacterium resists last-resort antibiotic ceftriaxone while maintaining a robust growth rate.
Congratulations to Justin Watkins who has been selected as a 3-yr SPIRE Fellow beginning Sept. 1st
Congratulations to Dr. Justin Watkins (postdoc in Alan Jones Lab) who has been selected as a 3-yr SPIRE Fellow beginning Sept 1st 2018.
Alfred Dolge Receives ePRO Vendor Award
Alfred Dolge receives the UNC ConnectCarolina Award for "The Most ePro Vendor Catalog Transactions!"
Jen Jen Yeh named Smithies Investigator
The UNC School of Medicine has selected Jen Jen Yeh, MD, professor and vice chair of research for the department of surgery, and joint professor of pharmacology, for one of two annual awards in honor of Oliver Smithies, UNC’s first Nobel Prize winner.
Scientific Breakthrough Could Lead to Better Antipsychotic Drugs
Published in Nature, research from the lab of Bryan L. Roth, MD, PhD, Distinguished Professor of Pharmacology, revealed the first-ever crystal structure of the dopamine 2 receptor bound to an antipsychotic drug – a much-needed discovery in the quest to create effective drugs with fewer side effects to treat bipolar disorder, schizophrenia, and other conditions.
UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State
The lab of Jean Cook, PhD, joint professor in the department of pharmacology, found how a chain of proteins called an MCM complex could enable the fast cell-division that makes some forms of cancer so dangerous.
Scientists Take a Big Step toward Building a Better Opioid
In a paper published in Cell, research led by Bryan Roth, MD, PhD, and Roth lab members, Tao Ch, PhD and Daniel Wacker, PhD, show how to activate only one kind of brain receptor vital for pain relief. This receptor is not involved in addiction or respiratory depression that leads to death – the most severe side effects of opioid use.
UNC School of Medicine to Launch Computational Medicine Program
Led by Timothy Elston, PhD, and Chuck Perou, PhD, the university-wide program aims to advance personalized medicine for patients.
A microscope maker
Wesley Legant, PhD, Assistant Professor in Pharmacology, is highlighted in a Nature article on a do-it-yourself approach to microscopy that lead to the development of light sheet microscopy.
NIH renews grant funding the Bowles Alcohol Research Center
The center, established 20 years ago and led by Fulton Crews, PhD, Distinguished Professor in Pharmacology, will receive more than $8.7 million over five years to continue research on the effects of alcohol on the brain. Other pharmacology faculty who are PIs on the the grant are Clyde Hodge, PhD, Zoe McElligott, PhD, Tom Kash, PhD, Melissa Herman, PhD and Leslie Morrow, PhD.
Could this Protein Protect People against Coronary Artery Disease?
Research led by UNC’s Jonathan Schisler, PhD, Assistant Professor of Pharmacology, showed much lower levels of the protein CXCL5 in older people with clogged arteries.
How do adult brain circuits regulate new neuron production?
In a new study published in Cell Stem Cell, UNC School of Medicine neuroscientist Juan Song and colleagues discovered a long-distance brain circuit that controls the production of new neurons in the hippocampus.
Brian Jensen Receives The Hyman Battle Distinguished Excellence in Teaching Award and Delivers Whitehead Lecture
Brian Jensen, MD, assistant professor of medicine and pharmacology, delivered the 2017 Whitehead Lecture. The event, which serves as an unofficial convocation of the UNC School of Medicine, has been held annually since 1947.
CSF Students Give Research Presentations
Our 2017 Carolina Summer Fellowship students gave their research presentations today as they end the program. Congratulations to all!
Mackman to lead 4-year $1.5-million award study into role of clotting protease and receptor in the innate immune response to viral infections
UNC receives $1.5-million grant to study the role of a clotting protease and receptor in the innate immune response to viral infections. Nigel Mackman, PhD, Distinguished Professor of Medicine, and joint Professor of Pharmacology, is the principal investigator of a 4-year $1.5-million award from the National Heart Lung and Blood Institute. This grant will determine the role of thrombin activation of protease-activated receptor 1 in the innate immune response to viral infections.
Willis laboratory recognized by Society of Endocrinology for excellence in endocrine research
The Willis laboratory has been recognized by the Society of Endocrinology for excellence in endocrine research and practice and for contributions to the wider biomedical and biological sciences field. The award was chosen by a panel on the basis of originality, scientific content, presentation and contribution to the field. The award will be presented to Monte Willis, PhD, at the Society’s Annual BES Conference in Harrogate, UK on November 7.