Toutchkine, A., Han, W.G., Ullmann, M., Liu, T., Bashford, D., Noodleman, L., and Hahn, K.M. Experimental and
DFT studies: novel structural modifications greatly enhance the solvent sensitivity of live cell imaging dyes. J Phys Chem A.
111:10849-60, 2007. Click here for abstract.
Toutchkine, A., Nguyen, D.V., and Hahn, K.M. Merocyanine Dyes with Improved Photostability.Org. Lett.
9(15)2775-2777,
2007. Click here for abstract.
Pertz, O., L. Hodgson, R. R. Klemke, and K.M. Hahn. Spatio-temporal dynamics of RhoA activity in migrating cells. Nature, 440(7087):1069-1072, 2006. Click here for abstract.
Subauste, M., O. Pertz, E. Adamson, C.E. Turner, S. Junger, K.M. Hahn. Vinculin Modulation of Paxillin-FAK Interactions
Regulates ERK to Control Survival and Motility. J Cell Biol., 165:171-181, 2004. Click here for abstract.
Nalbant, P., L. Hodgson, V. Kraynov, A. Toutchkine, K.M. Hahn. Activation of Endogenous Cdc42 Visualized in Living
Cells.Science, 305: 1615-1619, 2004. Click here for abstract.
Toutchkine, A., V. Kraynov, and K.M. Hahn. Solvent-Sensitive Dyes to Report Protein Conformational Changes in Living
Cells.J. Amer. Chem. Soc., 125:4132-4145, 2003. Click here for abstract.
Kraynov, V. S., Chamberlain, C. E., Bokoch, G. M., Schwartz, M. A., Slabaugh, S., and K. M. Hahn. Localized Rac activation
dynamics visualized in living cells. Science, 290:333-337, 2000. Click here for abstract.
Bark, S. J., Schmid, S., and K. M. Hahn. A highly efficient method for site-specific modification of peptides after
chemical synthesis.J. Am. Chem. Soc., 122 (15): 3567-3573, 2000. Click here for abstract.
Collaborative applications of live cell tools
Birkenfeld, J., Nalbant, P., Bohl, B.P., Pertz, O.P., Hahn, K.M., and Bokoch, G.M. GEF-H1 modulates localized RhoA
activation during cytokinesis under the control of mitotic kinases.Developmental Cell.12(5): 699-712, 2007. Click here for abstract.
Van Keymeulen, A., Wong, K., Knight, Z.A., Govaerts, C., Hahn, K.M., Shokat, K.M., and Bourne, H.R. To stabilize neutrophil
polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front.J. Cell Biol., 174:437-445,
2006. Click here for abstract.
Shen, F., L. Hodgson, A. Rabinovich, O. Pertz, K.M. Hahn, and J.H. Price. Functional Proteomics for Cell Migration. Cytometry, 69(7):563-782, 2006. Click here for abstract.
Wong K., Pertz O., Hahn K. M., H.. Bourne. Neutrophil polarization: Spatiotemporal dynamics of RhoA activity support a
self-organizing mechanism. Proc Natl Acad Sci USA., 103(10):3639-44, 2006. Click here for abstract.
Gardiner, E.M., N. Pestonjamasp, B.P. Bohl, C. Chamberlain, K.M. Hahn and G.M.Bokoch. Spatial and Temporal Analysis of
Rac Activation During Live Neutrophil Chemotaxis: Roles in Leading Edge Extension and Tail Retraction.Current
Biology, 12: 2029-2034, 2002. Click here for abstract.
Del Pozo, M.A., W.B. Kiosses, N.B. Alderson, N. Meller, K.M. Hahn, and A. Schwartz. Integrin-regulated membrane
translocation of GTP-Rac induces localized interaction with effectors due to dissociation of RhoGDI, Nature Cell
Biology, 4:232-239, 2002. Click here for abstract.
Questions or Comments? Contact Hahn Lab.
Hahn Lab, UNC Chapel Hill, Department of Pharmacology
