Alumni

Recent Graduates, Department of Pharmacology

Jayme Warischalk, Ph.D.Jayme Warischalk

Graduation Date: 03/18/2015
Advisor: R. Jude Samulski
Title of Dissertation:  Uncovering structural components of the adeno-associated viral capsid that can be modified to enhance clinical gene therapy applications."  
Current Position: Academic Editor for Research Square in Durham, NC.

Meagan Eldridge, M.S.Meagan Eldridge Yeh lab

Graduation Date: 11/17/2014
Advisor: Jen Jen Yeh
Title of M.S. Thesis:  "Identifying biomarkers of response to modified FOLFIRINOX regimens using patient derived xenograft mouse models of pancreatic ductal adenocarcinoma" 
Current Position: Medical/Clinical Writer at WebbWrites, LLC in Durham, NC.

Ernesto Perez-Chanona, Ph.D.Ernesto Perez Chanona 2

Graduation Date: 9/18/2014
Advisor: Christian Jobin
Title of Dissertation:  "Microbial signaling in intestinal ischemia/reperfusion injury response." 
Current Position: Postdoctoral Fellow at the National Cancer Institute, Bethesda, MD

Kayla Knilans, Ph.D.Kayla Knilans

Graduation Date: 8/7/2014
Advisor: Alex Duncan
Title of Dissertation:  "The role of lytic transglycosylases LtgA and LtgD in innate immune recognition and pathogenesis of Neisseria gonorrhoeae." 
Current Position: Postdoctoral Fellow at the National Institutes of Health (NIH) in the lab of Tom Wynn

Sarah Nicolson, Ph.D.Sarah Nicolson

Graduation Date: 7/7/2014
Advisor: Jude Samalski
Title of Dissertation: "Understanding mechanisms of Adeno-associated virus vector transduction through pharmacological and biological approaches"
Current Position:

Jeran Stratford, Ph.D.Jeran Stratford - Yehlab

Graduation Date: 7/3/2014
Advisors: Jen Jen Yeh and Channing Der
Title of Dissertation: "Aberrant gene expression:  diagnostic markers and therapeutic targets for pancreatic cancer"
Current Position: Student in M.S. program in Biostatistics, UNC School of Public Health

Doug Ornoff, Ph.D.Doug Ornoff

Graduation Date: 6/19/2014
Advisor: Nancy Allbritton
Title of Dissertation: "Development of a cellular analysis platform featuring arrays of patterned microwells fabricated atop permeable supports"
Current Position: Postdoctoral Fellow in Dr. Boucher's lab at UNC School of Medicine, Cystic Fibrosis/Pulmonary Research & Treatment Center

Kate White, Ph.D.Kate White

Graduation Date: 4/7/2014
Advisor: Bryan Roth
Title of Dissertation: "Identification of biased kappa opioid receptor ligands for in vivo probing of specific signal transduction pathways?"
Current Position: Postdoctoral Fellow (in Dr. Ray Stevens lab), Dept. of Biological Sciences and Chemistry, University of Southern California, The Bridge Institute, Los Angeles, CA

Justin English, Ph.D.Justin English

Graduation Date: 4/1/2014
Advisor: Henrik Dohlman
Title of Dissertation: "Stress on a Deadline: Setting a Timer for Adaptation in Living Cells"
Current Position: Scientist, National Institute on Drug Abuse (NIDA)

Daniel Dominguez, Ph.D.Daniel Dominguez

Graduation Date: 3/14/2014
Advisor: Zefeng Wang
Title of Dissertation: "Transcriptome Dynamics During the Mammalian Cell Cycle."
Current Position: Postdoctoral Fellow, Dept. of Biology, MIT, Cambridge, MA

Bryan Richardson, Ph.D.Bryan Richardson

Graduation Date: 12/15/2013
Advisor: Gary Johnson
Title of Dissertation: "Defining the Molecular Mechanisms of the Cerebral Cavernous Malformation Proteins"
Current Position: Patent Agent, Womble Carlyle Sandridge & Rice LLP, Durham, NC

Lauren Parker Huff, Ph.D.Lauren Parker

Graduation Date: 12/15/2013
Advisor: Adrienne Cox 
Title of Dissertation: "Impact of subcellular localization on oncogenic functions of the RhoGEF Ect2 and on its Rho GTPase targets"
Current Position: Postdoctoral Fellow, Emory University

Rebecca Sinnott, Ph.D.Rebecca Sinnott

Graduation Date: 12/4/2013
Advisor: Angelique Whitehurst
Title of Dissertation: "Mechanisms that promote liberation of mitotic stress-induced death"
Current Position: Postdoctoral Fellow, SUNY-Albany, New York

Pei-Hsuan Chu, Ph.D.Pei-Hsuan Chu

Graduation Date: 10/24/13
Advisor: Klaus Hahn
Title of Dissertation:  "Dissecting the role of kinase isoforms using new tools for activation and inactivation of kinases in vivo"
Current Position: Postdoctoral Fellow, NIH at NCATS

Daniel Urban, Ph.D.Siderovski Lab

Graduation Date: 10/21/13
Advisor: Bryan Roth
Title of Dissertation:"Pharmacosynthetic Modulation of Serotonin Networks."
Current Position: Research Scientist, Biology [C], NIH, National Center for Advancing Translational Sciences, Rockville, MD

Marty Whittle, Ph.D.Johnson Lab

Graduation Date: 8/12/13
Advisor: Gary Johnson 
Title of Dissertation: "Targeting the Triple-Negative Breast Cancer Kinome with Chemical Proteomics"
Current Position: Postdoctoral Fellow at Fred Hutchinson Cancer Research Center, Seattle, Washington

Ross Dubose, Ph.D.Ross Debose

Graduation Date: 7/29/13
Advisor: Rob Nicholas 
Title of Dissertation: "P2Y Receptor Trafficking in Polarized Epithelial Cells"
Current Position: Scientific Manuscript Submission Scanner at American Journal Experts, Durham, NC

Chris Dibble, Ph.D.Chris Dibble

Graduation Date: 6/5/13
Advisor: Gary Johnson 
Title of Dissertation: "Defining the Cerebral Cavernous Malformation signaling network in endothelial cells"
Current Position: Returned to UNC-Medical School to complete MD (enrolled in MD/PHD program)

Ryan Phillips, Ph.D.Ryan Phillips

Graduation Date: 5/30/13
Advisor: Nancy Allbritton 
Title of Dissertation: "Development of a Novel Assay of Protein Tyrosine Phosphatase Activity in Single Cells Using Capillary Electrophoresis"
Current Position: Returned to UNC-Medical School to complete MD (enrolled in MD/PHD program)

Dustin Bosch, Ph.D.Dustin Bosch

Graduation Date: 3/21/13
Advisor: David Siderovski
Title of Dissertation: "Elucidating G protein signaling in Entamoeba histolytica"
Current Position: Returned to UNC-Medical School to complete MD (enrolled in MD/PHD program)

Tim Martin, Ph.D.Tim Martin

Graduation Date: 3/19/13
Advisor: Channing Der
Title of Dissertation: "The role and regulation of Ral GTPases in oncogenesis"
Current Position: Postdoctoral Fellow, Medicine, Brigham and Woman’s Hospital/Harvard

Marty Farrell, Ph.D.Roth Lab

Graduation Date: 2/27/13
Advisor: Bryan Roth
Title of Dissertation: "Pharmacosynthetics and the Cell-Type Specific Control of Neuronal Signaling"
Current Position: Postdoctoral Fellow, Genetics Dept., UNC-CH

Suzanne Minton, Ph.D.Suzanne Minton

Graduation Date: 1/15/13
Advisor: Ken McCarthy
Title of Dissertation: "Stimulating glial Gq-coupled GPCR pathways blocks acute pain and itch"
Current Position: Marketing specialist at the Certara Corporation, Cary, NC

Nicole Vincent Jordan, Ph.D.Nicole Vincent-Jordan

Graduation Date: 9/6/12
Advisor: Gary Johnson
Title of Dissertation: "Epigenetic Regulation of Epithelial-Mesenchymal Transition in Epithelial Stem Cells and Triple Negative Breast Cancer"
Current Position: Postdoctoral Research Fellow, Massachusetts General Hospital Cancer Center/Harvard

Margaret Duncan, Ph.D. Margaret Duncan

Graduation Date: 6/22/12
Advisor: Rob Nicholas
Title of Dissertation: "Probing the mechanisms of antibiotic resistance in the gonococcus"
Current Position: Manager, Medical Professional Services and Lead Medical Content Reviewer, Alkermes, Boston, MA

Asya Borikova, Ph.D. Michal Nagiec

Graduation Date: 5/25/12
Advisor: Gary Johnson
Title of Dissertation: "Cerebral Cavernous Malformations is a disease of dysregulated expression of RhoA and Rap1 proteins"
Current Position: Postdoctoral Fellow, Medicine, Massachusetts General Hospital/Harvard

Brent Hehl, M.S. Brent Hehl

Graduation Date: 5/9/12
Advisor: Howard McLeod
Title of M.S. Thesis: "Identifying genetic factors affecting anthracycline-induced cytotoxcity."
Current Position: Strategic Account Executive, DiscoveRx

Jasmyn Adams, M.S. Jasmyn Dardy

Graduation Date: 4/20/12
Advisor: Channing Der
Title of M.S. Thesis: "Validation of PAK Kinases for the Development of Novel Therapeutics for Pancreatic Cancer Treatment"
Current Position: Clinical Monitoring Associate at Parexel, Research Triangle Park, NC

Jason Goldsmith, Ph.D. Jason Goldsmith

Graduation Date: 4/16/12
Advisor: Christian Jobin
Title of Dissertation: ""Mechanisms of mu opioid receptor mediated protection from multiple models of acute injury"
Current Position: Resident Physician, University of Michigan Health System, Ann Arbor, MI

Xin Zou, M.S. Xin Zou

Graduation Date: 3/30/12
Advisor: Klaus Hahn
Title of M.S. Thesis: "Using Aureochrome to Control Protein-Protein Interactions with Light"
Current Position: Senior Associate at Discover Financial Services, Chicago, IL

Allison McMullen, Ph.D. Allison McMullen

Graduation Date: 11/1/11
Advisor: Ken McCarthy
Title of Dissertation: "Cellular, histological and behavioral changes in the pathogenesis of hydrocephalus in the Ro1 mouse model"
Current Position: Editing Operations Manager, American Journal Experts, Durham, NC

Michal Nagiec, Ph.D. Michal Nagiec

Graduation Date: 6/14/11
Advisor: Henrik Dohlman
Title of Dissertation: "Coordination of MAP Kinase Signaling During Cell Fate Decisions."
Current Position: Postdoctoral Fellow, Cell Biology, Harvard Medical School

Chris Welch, Ph.D. High Honors, M.D.Chris Welch

Graduation Date: 5/20/11
Advisor: Klaus Hahn
Title of Dissertation: "Revealing Rho GTPase Dynamics in Cell Migration."
Current Position: Resident Physician, UNC-School of Medicine

Katy Cappell, Ph.D., M.D.Katy Cappell

Graduation Date: 5/13/11
Advisor: Angelique Whitehurst
Title of Dissertation: "Symplekin and Transforming Acidic Coiled-Coil Containing Protein 3 Support the Cancer Cell Mitotic Spindle."
Current Position: Resident Physician, Internal Medicine, Stanford Hospital and Clinics

Eric Zimmerman, Ph.D. Eric Zimmerman

Graduation Date: 3/24/11
Advisors: Lee Graves
Title of Dissertation: "Lyn kinase regulation of microRNA and Mcl-1 in drug-resistant myelogenous leukemia."
Current Position: Pharmacokineticist at PPD, Richmond, VA

Sarah Rogan, Ph.D., M.D.Sarah Rogan

Graduation Date: 2/14/11
Advisors: Bryan Roth
Title of Dissertation: "Remote control of neuronal signaling in vivo."
Current Position: Resident Physician, Univ. of Texas Medical Branch, Galveston, TX

Steven Cappell, Ph.D. Steven Cappell

Graduation Date: 12/16/10
Advisors: Henrik Dohlman
Title of Dissertation: "Systematic Analysis of Essential Genes Reveals New Regulators of G protein Signaling."
Current Position: Postdoctoral Fellow, Stanford University

John Bauman, Ph.D. John Bauman

Graduation Date: 12/6/10
Advisor: Ryszard Kole
Title of Dissertation: "Modification of Bcl-x and Mcl-1 pre-mRNA splicing using splice-switching oligonucleotide."
Current Position: Study Manager at ILS Genomics in Morrisville, NC

Aurelie Gresset, Ph.D.Aurelie Gressett

Graduation Date: 8/5/10
Advisor: John Sondek
Title of Dissertation: "Mechanism of phosphorylation-induced activation of phospholipase C-gamma isozymes"
Current Position: Postdoctoral Fellow, Ecole Normale Supérieure, Paris, France

Ellen Stevens, Ph.D. Ellen Stevens

Graduation Date: 6/3/10
Advisor: Channing Der
Title of Dissertation: "Identification of Novel Therapeutic Approaches and Targets for the Treatment of Ovarian Carcinoma"
Current Position: Senior Researcher for Assay Development at Inanovate

Adam Kimple, Ph.D., M.D.Adam Kimple

Graduation Date: 5/5/10
Advisor: David Siderovski
Title of Dissertation: "R4 and R12 subfamily RGS proteins-Structure, funtion, and emerging chemical biology"
Current Position: Resident Physician, Otolaryngology/Head and Neck Surgery, UNC School of Medicine

Jamie Alan Olsen, Ph.D. Jamie Alan

Graduation Date: 3/15/10
Advisor: Adrienne Cox
Title of Dissertation: "Tyrosine kinase modulation of trafficking and biological functions of the atypical Rho GTPase, Wrch-1"
Current Position: Assistant Professor of Pharmacology, Central Michigan University

Tanya Zand, Ph.D. Tanya Zand

Graduation Date: 3/12/10
Advisor: Channing Der
Title of Dissertation: "Ras signaling through the RalGEF-Ral pathway in C. elegans"
Current Position: Scientific Manuscript Submission Scanner at American Journal Experts, Durham, NC

Tiffany K. Ricks, Ph.D. Tiffany Ricks

Graduation Date: 2/26/2010
Advisor: Ken Harden
Title of Dissertation: "Signal Regulation of Protease-activated Receptor-2 and Structural Determinants of Gaq -dependent Activation and Deactivation of Phospholipase C-ß"
Current Position: Pharmacologist, FDA, Washington, DC

Randal Hand, Ph.D. Randal Hand

Graduation Date: 12/29/09
Advisor: Franck Polleux
Title of Dissertation: "The regulation of cortical development by Neurogenin2"
Current Position: Senior Postdoctoral Fellow in Dr. Alex Kolodin's laboratory at Johns Hopkins University

Jarrod Johnson, Ph.D. Jarrod Johnson

Graduation Date: 9/11/09
Advisor: R. Jude Samulski
Title of Dissertation: "Virion components and subcellular parameters that impact trafficking, nuclear targeting, and infection of adeno-associated virus"
Current Position: Staff Scientist at Seattle Biomed

Dionne R. Glast, Ph.D.Dionne Glast

Graduation Date:8/27/2009
Advisor: Rob Nichols
Title of Dissertation: "G Protein-coupled Receptor Signaling: Role of PAR-2 in Breast Carcinoma Metastasis and Regulation of Agonist-Promoted Internalization of P2Y1 Receptors"
Current Position: Medical Writer, INC Research, Raleigh, NC

Angela Russo, Ph.D. Angela Russo

Graduation Date: 5/18/09
Advisor: Pilar Blancafort
Title of Dissertation: "Delineating and rationally perturbing signaling mechanisms involved in metastasis"
Current Position: Visiting Research Assistant Professor, Dept. of Medicinal Chemistry and Pharmacology, University of Illinois, Chicago, IL

Sabrice Guerrier, Ph.D. Sabrice Guerriere

Graduation Date: 3/31/09
Advisor: Franck Polleux
Title of Dissertation: "Cellular and molecular mechanisms underlying srGaP2 function during neuronal development"
Current Position: Assistant Professor of Biology, Millsap College, Jackson, MI

Elizabeth Sweger Butala, Ph.D.Elizabeth Sweger

Graduation Date: 3/27/09
Advisor: Ken McCarthy
Title of Dissertation: "Expression of the Gi-coupled RASSL Ro1 in GFAP-positive cells: a novel model of hydrocephalus"
Current Position: Staff Scientist, ABC Laboratories, Columbia, Missouri

Lisa Stalheim Crose, Ph.D.Lisa Stalheim Crose

Graduation Date: 3/24/09
Advisor: Gary L. Johnson
Title of Dissertation: "Regulation and Function of the Cerebral Cavernous Malformation 2 Protein"
Current Position: Senior Research Associate, Duke University Medical Center, Durham, NC

Katie Kelm, Ph.D.Katie Kelm

Graduation Date: 3/23/09
Advisor: George Breese
Title of Dissertation: "Investigating the Mechanism of Ethanol-enhanced GABA Release"
Current Position: Associate Medical Writer, PPD, RTP, NC

Nina DiPrimio, Ph.D.Nina DiPrimio

Graduation Date: 3/20/09
Advisor: R. Jude Samulski
Title of Dissertation: "Surface loop dynamics of a Parvovirus"
Current Position: Scientist, Peristein Labs, San Francisco, CA

Ingrid Fricks, Ph.D.Ingrid Fricks

Graduation Date: 3/18/09
Advisor: Ken Harden
Title of Dissertation: "Molecular Pharmacology and Function of the P2Y14 Receptor"
Current Position: Medical Writer, INC Research, Raleigh, NC

Justin Brown, Ph.D.Justin Brown

Graduation Date: 11/7/08
Advisor: Richard Mailman
Title of Dissertation: "Structural basis for ligand-binding and activation of D1-like dopamine receptors"
Current Position: Business Development Consultant, Meryz, Raleigh, NC

Michael J. Lee, Ph.D.Michael Lee

Graduation Date: 4/8/08
Advisor: Henrik Dohlman
Title of Dissertation: "Activation of G protein signaling by a non-receptor exchange factor"
Current Position: Assistant Professor at U. Mass Medical School

Amanda C. Sharko, Ph.D.Amanda Sharko

Graduation Date: 4/1/08
Advisor: Clyde Hodge
Title of Dissertation: "The role of metabotropic glutamate receptors and associated cell signaling pathways in the acute sedative-hypnotic effects of ethanol"
Current Position: Postdoctoral Fellow, University of South Carolina, Columbia, SC

Mariya Chhatriwala, Ph.D.Mariya Chhatriwala

Graduation Date: 3/31/08
Advisor: John Sondek
Title of Dissertation: "Defining diverse mechanisms that regulate the activity of Dbl-family guanine nucleotide exchange factors"
Current Position: Staff Scientist, HIPSCI/Pancreatic Differentiation at Wellcome Trust Sanger Institute, Univ. of Cambridge, England

Ryan Shanks, M.S.Ryan Shanks

Graduation Date: 3/26/08
Advisor: Henrik Dohlman
Title of M.S. Thesis: "GAP independent RGS action"
Current Position: Practicing Physician

Donita Brady, Ph.D.Donita Brady

Graduation Date: 3/17/08
Advisor: Adrienne Cox
Title of Dissertation: "The transforming Rho family GTPase, Wrch-1, regulates epithelial cell morphogenesis through modulating cell junctions and actin cytoskeletal dynamics"
Current Position: Research Associate, Duke University

Jiyoung Cha, Ph.D.Jiyoung Cha

Graduation Date: 7/24/07
Advisor: Channing Der
Title of Dissertation: "The role and mechanism of fibroblast growth factor receptor 2 in cellular transformation"
Current Position: Research Associate in Dr. Solomon Snyder's lab at Johns Hopkins University

Bin Zhao, Ph.D.Bin Zhao

Graduation Date: 7/11/07
Advisor: Leslie Parise
Title of Dissertation: "Regulation of cell survival by CIB1, a new modulator of 3-phosphoinositide-dependent protein kinase 1 (PDK1)"
Current Position: Medical Affairs Mgr., Merck in China

Eric Wauson, Ph.D.Eric Wauson

Graduation Date: 7/3/07
Advisor: Lee Graves
Title of Dissertation: "The Regulation of the Pyrimidine Biosynthetic Protein CAD by Phosphorylation and Protein-Protein Interactions"
Current Position: Assistant Professor, Physiology and Pharmacology, Des Moines University

Matthew Higgins, Ph.D.Matthew Higgins

Graduation Date: 7/2/07
Advisor: Lee Graves
Title of Dissertation: "Regulation of Human Cytidine Triphosphate Synthetase 1 by Phosphorylation and Interacting Proteins"
Current Position: Postdoctoral Fellow, Gladstone Inst., University of California at San Francisco

Christopher Johnston, Ph.D.Christopher Johnston

Graduation Date: 6/29/07
Advisor: David Siderovski
Title of Dissertation: "Structural Insights into the Molecular Basis of Heterotrimeric G-protein Signal Transduction"
Current Position: Assistant Professor, Biology, University of New Mexico

YiXing (Emily) Zhou, Ph.D.Yi Xing Emily Zhou

Graduation Date: 6/28/07
Advisor: Ken Harden
Title of Dissertation: "Cloning and Characterization of a Novel Phospholipase C Isozyme, PLC-n2"
Current Position: Postdoctoral Fellow, National Institute of Environmental Health Sciences

Mohamed Zayed, Ph.D.Mohamed Zayed

Graduation Date: 6/6/07
Advisor: Leslie Parise
Title of Dissertation: "ClB1 Mediated Regulation of Endothelial Cells and Pathological Angiogenesis"
Current Position: Assistant Professor, Surgery/Vascular Surgery at Washington University, St. Louis, MO

Rafael Rojas, Ph.D.Rafael Rojas

Graduation Date: 5/21/07
Advisor: John Sondek
Title of Dissertation: "Coordinating the activation of RhoA by diverse RhoGEFs: SmgGDS and G-alpha-q-responsive Dbl family guanine nucleotide exchange factors"
Current Position: Scientist I at Dart Neuroscience

James Ferguson, Ph.D., M.D.James Ferguson

Graduation Date: 5/10/07
Advisor: Cam Patterson
Title of Dissertation: "Ankyrin Repeat and SOCS Box Protein 4 (ASB4) is a Hydroxylation Substrate of Factor Inhibiting HlF1a(FlH) and Promotes Vascular Differentiation via an Oxygen-Dependent Mechanism"
Current Position: Medicine Resident, Massachusetts General Hospital

Holly Gentry, Ph.D.Holly Gentry

Graduation Date: 5/3/07
Advisor: Leslie Parise
Title of Dissertation: "Structure and Biochemical Characterization of CIB1"
Current Position: Medical Science Writer, Education and Training Systems International, Chapel Hill, NC

Jason Seifert, Ph.D.Jason Seifert

Graduation Date: 3/30/07
Advisor: Ken Harden
Title of Dissertation: "Regulation of phospholipase C-epsilon by Rho and Ras Family GTPases"
Current Position: Associate at Womble Carlyle Sandridge & Rice LLP, Raleigh, NC

Breann Wolfe Barker, Ph.D.Breann Wolf

Graduation Date: 3/26/07
Advisor: JoAnn Trejo
Title of Dissertation: "Clathrin-dependent Internalization of Protease-activated Receptor-1: Regulation by Ubiquitination and Epsin"
 Current Position: Senior Research Scientist at QPS, LLC, Philadelphia, PA

Dayle Houston, Ph.D.Dayle Houston

Graduation Date: 3/23/07
Advisor: Ken Harden
Title of Dissertation: "Agonist-Promoted Regulation of the P2Y1 Receptor: Quantification of Native and Recombinant Receptors with the Novel Radioligand [32P]MRS2500"
Current Position: Director, Global Medical Writing, PPD, Inc., Research Triangle Park, NC

Marielle Yohe, Ph.D., M.D.Marielle Yohe

Graduation Date: 3/19/07
Advisor: John Sondek
Title of Dissertation: "Auto-inhibition of Tim and Related Dbl-family Rho GEFs by an N-terminal Helical Motif"
Current Position: Clinical Fellow, Johns Hopkins Hospital, Division of Pediatric Oncology

Melinda Hains Willard, Ph.D.Melinda Willard

Graduation Date: 10/27/06
Advisor: David Siderovski
Title of Dissertation: “Multiple Domain ‘Nexus’ Proteins in Receptor-Mediated Cell Signaling”
Current Position: Research Scientist, Eli Lily, Indianapolis, IN

Sheritha P. Lee, Ph.D.Sheritha Lee

Graduation Date: 6/19/06
Advisor: Leslie Parise
Title of Dissertation: “Chronic Inflammation in Sickle Cell Disease: Potential Role of Platelets and the Inflammatory Mediator CD40L”
Current Position: Associate Director, Clinical Development at Trevena, Inc

Qian Dai, Ph.D., M.D.

Graduation Date: 5/06
Advisor: Cam Patterson
Title of Dissertation: “The cochaperone and ubiquitin ligase CHIP in protein quality control”
Current Position: Molecular Genetic Fellow, University of Alabama, Birmingham

Biljania Djukic, Ph.D.Biljania Djukic

Graduation Date: 4/11/06
Advisor: Ken McCarthy
Title of Dissertation: “Role of the inward rectifying K+ channel, Kir4.1, in astrocyte physiology and neuronal excitability”
Current Position: Staff Research Scientist, Gladstone Institutes, San Francisco, CA

May M. Paing, Ph.D.

Graduation Date: 8/25/05
Advisor: JoAnn Trejo
Title of Dissertation: "Regulation of Protease-activated Receptor 1 Signaling and Trafficking"
Current Position: Staff Scientist, Washington University Medical School, St. Louis, Department of Molecular Microbiology & Microbial Pathogenesis

Nathan Allen, M.S.

Graduation Date: 7/28/05
Advisor: Jude Samulski
Title of M.S. Thesis: "Investigation of the Potential for Adeno-Associated Virus Type 5 to Establish Latency by Integration"
Current Position: Product Marketing Manager, Thermo-Scientific, Pittsburgh, PA

Patricia Joyce Keller, Ph.D.

Graduation Date: 7/5/05
Advisor: Adrienne Cox
Title of Dissertation: "Characterization of the small GTPase Rac3 in signaling and transformation"
Current Position: Scientist, Constellation Pharmaceuticals, Boston, MA

Anurag Singh, Ph.D.

Graduation Date: 5/16/05
Advisor: Channing Der
Title of Dissertation: "The Role of Divergent Rho Family Members Rac1b and Rnd3 in Cellular Transformation and Oncogenesis"
Current Position: Assistant Professor, Boston University, Pharmacology and Medicine, Division of Hematology and Medical Oncology 

Scott Oloff, Ph.D.

Graduation Date: 4/20/05
Advisor: Richard Mailman, Alex Tropsha
Title of Dissertation: "Development of Computer Aided Drug Discovery Methods Based on Machine Learning Techniques and Application to the Dopamine D1 Receptor"
Current Position: Head of IT Research, Development, and Medicine Enablement, Boehringer Ingelheim

Vivian Choi, Ph.D.

Graduation Date: 4/1/05
Advisor: Jude Samulski
Title of Dissertation: "The Involvement of DNA Replication and Repair Pathways in DNA Recombination Utilizing Viral DNA Terminal Repeat Hairpin Structures"
Current Position: Investigator, Novartis, Boston, MA

Matthew Edin, Ph.D.

Graduation Date: 3/29/05
Advisor: Rudy Juliano
Title of Dissertation: "Role of PAK and PKA in Adhesion-Dependent ERK Activation by EGF"
Current Position: Staff Scientist, Environmental Cardiopulmonary Disease Group, Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences  (NIEHS)

Thomas Hilder, Ph.D.Thomas Hilder

Graduation Date: 3/18/05
Advisor: Lee Graves
Title of Dissertation: "Phosphorylase Kinase and MAP Kinase Regulation During Skeletal Muscle Apoptosis and Atrophy"
Current Position: Senior Research Scientist I, Grifols, RTP, NC

Shannon Penland, Ph.D.

Graduation Date: 3/4/05
Advisor: Leslie Morrow
Title of Dissertation: "Effects of Ethanol on Biosynthesis of GABAergic Neurosteroids"
Current Position: Director, Regulatory Affairs, Pearl Therapeutics, Raleigh, NC

Erik Bodor, Ph.D.

Graduation Date: 2/21/05
Advisor: Ken Harden
Title of Dissertation: "Purification of the Human P2Y12 Receptor: Ligand Binding, G Protein Coupling, and Regulation by RGS Proteins"
Current Position: CFO & VP Research, Cognifem LLC, Boder Laboraries, Inc., Miami, FL

Sarah Leonard, Ph.D.

Graduation Date: 11/15/04
Advisor: Richard Mailman
Title of Dissertation: "The Amygdala: A Model System for Novel Dopamine Receptor Pharmacology"
Current Position: Postdoctoral Fellow, Wyeth Pharmaceuticals Neuroscience Division, Princeton, NJ

Todd Palmby, Ph.D.

Graduation Date: 7/6/04
Advisor: Channing Der
Title of Dissertation: "Components of Vav Mediated Transformation and Signal Transduction"
Current Position: Supervisory Pharmacologist, FDA

Rhonda Saunders Wilder, M.S.

Graduation Date: 3/24/04
Advisor: Adrienne Cox
Title of M.S. Thesis: "Regulation of Ect2, a Dbl family RhoGEF, by its Pleckstrin Homology (PH) domain"
Current Position: Clinical Research Coordinator, Duke University

Carolyn Coyne, Ph.D.

Graduation Date: 4/30/03
Advisor: Larry Johnson
Title of Dissertation: "Characterization and Modulation of Airway Tight Junctions"
Current Position: Associate Professor, University of Pittsburgh, Department of Microbiology & Molecular Genetics

Donnie Eddins, Ph.D.

Graduation Date: 11/24/03
Advisor: Bob Rosenberg
Title of Dissertation: "Regulation of alpha7 neuronal nicotinic acetylcholine receptors by extracellular divalent cations"
Current Position: Murine Behavioral Specialist at St. Jude Children's Research Hospital, Memphis, TN

Sally A. Hunsucker, Ph.D.

Graduation Date: 6/18/03
Advisor: Beverly Mitchell
Title of Dissertation: "The Role of Cytosolic 5’-Nucleotidase IA in Nucleoside Analog Metabolism"
Current Position: Research Associate, Armistead laboratory, UNC-CH Lineberger Cancer Center

Randall Kimple, Ph.D., M.D.

Graduation Date: 6/25/03
Advisor: David Siderovski
Title of Dissertation: "The Goloco Motifs of RGS12 and RGS14—Novel Regulators of G-Protein Signaling"
Current Position: Assistant Professor, University of Wisconsin, Department of Human Oncology

Mark K. Larson, Ph.D.

Graduation Date: 12/15/03
Advisor: Leslie Parise
Title of Dissertation: "Mechanisms and functions of glycoprotein VI-mediated Rap1 activation in platelets"
Current Position: Associate Professor, Augustina College, Department of Biology

Aylin Ulku, Ph.D., M.D.

Graduation Date: 5/16/03
Advisor: Channing Der
Title of Dissertation: "RAS Regulation of Gene Expression in Ovarian Carcinogenesis"
Current Position: Assistant Professor, University of California at San Francisco, Department of Medicine

Amy Brinson, Ph.D.

Graduation Date: 8/22/02
Advisor: Ken Harden
Title of Dissertation: "Differential Regulation of Uridine Nucleotide-activated P2Y4 and P2Y6 Receptors"
Current Position: Scientific writer, IMFORM GmbH, International Clinical Research

Chris Herold, Ph.D.

Graduation Date: 8/12/02
Advisor: Rob Nicholas
Title of Dissertation: "Nucleotide Selectivities of the Human and Rat P2Y4 Receptors and Pharmacological Analysis of Chimeric Human/Rat P2Y4 Receptors"
Current Position: Senior Regional Medical Liaison, Amgen Cardiovascular

Peter Sazani, Ph.D.

Graduation Date: 7/26/02
Advisor: Ryszard Kole
Title of Dissertation: "The Role of Chemical Structure in the Delivery and Activity of Antisense Oligonucleotides"
Current Position: Executive Director, Medical Affairs at Sarepta Therapeutics, Cambridge, Massachusetts

Melanie Olesky, Ph.D.

Graduation Date: 6/10/02
Advisor: Rob Nicholas
Title of Dissertation: "The Mechanism of Porin-mediated Antibiotic Resistance in Neisseria gonorrhoeae"
Current Position: Medical Science Liason for Cephalon Pharmaceuticals

John Lambert, Ph.D.

Graduation Date: 5/14/02
Advisor: Channing Der
Title of Dissertation: "Rac: Upstream Activation and Downstream Signaling"
Current Position: Manager, Business Development, Invitrogen Corporation

Patrick Hines, Ph.D., M.D.

Graduation Date: 3/22/02
Advisor: Leslie Parise
Title of Dissertation: "Intracellular Cyclic AMP Promotes Sickle RBC Aggregation and Adhesion to Laminin"
Current Position: Assistant Professor, Pediatrics, School of Medicine, Wayne State University & Associate, Department of Physiology, Children's Hospital of Michigan, Detroit, MI

Jason Kralic, Ph.D.

Graduation Date: 10/3/02
Advisor: Leslie Morrow
Title of Dissertation: "GABAA Receptor α1 Subunity Knockout Mice Exhibit Plasticity of Gabaergic Function and Behavior"
Current Position: Founder and Principal Advisor at Innervate BD Solutions, Research Triangle Park, NC

Danielle Mercatante Carrick, Ph.D.

Graduation Date: 10/11/02
Advisor: Ryszard Kole
Title of Dissertation: "Modification of the Alternative Splicing Pattern of BCL-x pre-mRNA: Induction of Cell Death and Chemo-sensitization of Cancer Cells"
Current Position: Senior Study Director, Westat, Rockville, MD

Peter Ward, Ph.D.

Graduation Date: 1/28/02
Advisor: Dhiren Thakker
Title of Dissertation: "Phospholipase C as a Regulator of Epithelial Tight Junction Permeability: Molecular and Cellular Mechanisms"
Current Position: Research Scientist, Arena Pharmaceuticals, San Diego CA

Victoria Harding, Ph.D.

Graduation Date: 11/20/01
Advisor: Howard Rockman
Title of Dissertation: "Role of G Protein-Coupled Receptor Signaling in the Pathogenesis of Heart Failure"
Current Position: Postdoctoral fellow, UCSD, La Jolla CA

Kevin Pruitt, Ph.D.

Graduation Date: 11/6/01
Advisor: Channing Der
Title of Dissertation: "Ras and Rho Regulation of the Cell Cycle and Oncogenesis"
Current Position: Associate Professor, Department of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center

Jennifer Obernier, Ph.D.

Graduation Date: 6/8/01
Advisor: Fulton Crews
Title of Dissertation: "The Relationship between Binge Drinking, Neurodegeneration and Cognitive Dysfunction"
Current Position: Study Director, Inst. for Laboratory Animal Research, National Academy of Sciences, Washington DC

Terry Amiss, Ph.D.

Graduation Date: 4/6/01
Advisor: Jude Samulski
Title of Dissertation: "Investigation of the DNA Sequences Required for Site-specific Integration of Adeno-associate Virus Type 4"
Current Position: Research Scientist, Becton Dickinson Technologies, RTP NC

Julie Brittain, Ph.D.Julie Brittain

Graduation Date: 10/27/00
Advisor: Leslie Parise
Title of Dissertation: "Integrin-Associated Protein is an Agonist and Adhesion Receptor on Sickle Red Blood Cells"
Current Position: Assistant Professor, Biochemistry/Biophsics, UNC-Chapel Hill

Jung Weon Lee, Ph.D.Jung Weon Lee

Graduation Date: 7/11/00
Advisor: Rudy Juliano
Title of Dissertation: "The Role of Alpha 5 Beta 1 Integrin in Intestinal Epithelial Cell Survival "
Current Position: Associate Professor, Seoul National University, Korea

Mike Wheeler, Ph.D.

Graduation Date: 5/10/00
Advisor: Ron Thurman
Title of Dissertation: "Oxidative Stress and Hepatic Gene Delivery: Studies with Adenovirus and Adeno-associated Virus"
Current Position: Associate Professor, East Carolina University, Department of Nutrition Science

Erik Dahlstrand, M.S.

Graduation Date: 6/28/00
Advisor: Lee Graves
Title of M.S. Thesis: "Evidence of Unique Mitogen Activated Protein Kinase Localization to the Mitochondria"
Current Position: Research Scientist, Vertex Pharmaceuticals, Cambridge MA

Michelle Cunningham, Ph.D.

Graduation Date: 3/10/00
Advisor: Ken Harden
Title of Dissertation: "Regulation of Inositol Lipid Signaling at Multiple Levels through Protein Kinase C-promoted Phosphorylation"
Current Position: Patent Attorney