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Class schedules for the current semester are listed below.

Please email phcostudentservices@unc.edu to register for all PHCO courses.

Please note that for all classes: The instructor, in consultation with UNC officials, will monitor classroom conditions and make appropriate instructional adjustments to support achieving course learning outcomes.

BIOC/PHCO 690 – Macromolecular Crystallographic Methods II*

(2 cr hr)
M/W @ 1:25 – 3:20 PM (2/19 – 4/17)
Location: TBA
Course Instructor: De. Stuart Endo-Streeter

Macromolecular Crystallographic Methods II builds upon the data collection and reduction techniques taught in Methods I. Students will use datasets, either from their own research or supplied by the instructor, to train on modern software and learn best-practices to build, refine, and assess protein crystal and cryo-EM structures. Classes will be a mixture of lectures, introducing concepts and techniques, and labs, translating the lectures into practice.

PHCO 702 – Principles of Pharmacology and Physiology*

(3 cr. hr)
M/W/F @ 9:05 – 9:50 am 
Location: TBA
Course Director: Dr. Terry Kenakin

This graduate level course introduces students to the major areas of pharmacology and physiology and serves for a basis for advanced courses. Three lecture hours a week.

Registration is by permission of the instructor.  This is a graduate-level course.

Who can enroll: Anyone (BBSP, Undergrad and Non-PHCO)

Requisites: Prerequisite, CHEM 430; permission of the instructor for students lacking the prerequisite.

Course Syllabus

PHCO 730 – Seminar in Recent Advances in Pharmacology*

(1 cr. hr)
Thursday @ 10:00 am – 12:00 pm
Location: TBA (GMB 4007 or GMB 4095  **Please check back)
Course Instructor: Dr. Nick Brown

This graduate level course has been designed to help cultivate a variety of essential skills required to become successful in your scientific career. It is in part a journal club and a writing class. It is designed to provide preparation for the doctoral oral exam. This preparation includes learning to evaluate research designs and pharmacology literature.

Students meet as a group with faculty members to develop skills in critical reading and to summarize and discuss selected aspects of current pharmacological literature. Fall and Spring

Open to Pharmacology students only.

BIOC/PHCO 740 – Contemporary Topics in Cell Signaling: Phosphorylation Control & Protein Kinases*

( 1 cr hr)
T/Th @ TBD (January 11 – February 8)
Location: 4095 GMB
Course Instructor: Dr. Lee Graves

This graduate-level course is an in-depth analysis of how protein kinases and protein phosphorylation regulates key aspects of cell signaling. This class is one of the “Contemporary Topics in Cell Signaling” modules.

Permission of the instructor. Required preparation, coursework in biochemistry, pharmacology and/or cell & molecular biology.

BIOC/PHCO 741– Contemporary Topics in Cell Signaling: GTPases*

(1 cr hr)
T/Th @ 11:00 am – 12:15 pm (February 15 – March 21)
Location: TBA
Course Instructor: Dr. Kirsten Bryant

This graduate-level course conveys principles of signal transduction controlled by GTPases and emphasizes in-depth discussion of current literature and unanswered questions. This class is one of the “Contemporary Topics in Cell Signaling” modules.

Permission of the instructor. Required preparation, coursework in biochemistry, pharmacology, and/or cell & molecular biology.

BIOC/PHCO 742 – Contemporary Topics in Cell Signaling: Cell Cycle Control*

(1 cr hr)
T/Th @ 9:00 – 10:30 am (March 26 – April 25)
Location: TBA
Course Instructor: Dr. Mike Emanuele

This graduate-level course conveys principles of eukaryotic cell proliferation control emphasizing in-depth discussion of current literature and unanswered questions. This class is one of the Contemporary Topics in Cell Signaling modules.

Permission of the instructor. Required preparation, coursework in biochemistry and/or cell & molecular biology.

BIOC/PHCO 744 – Topics on Stem Cells and Development*

(2 cr hr)
T/Th @ 9:30 – 10:45 am (February 13 – April 25)
Location: TBA
Course Instructor: Dr. Jiandong Liu

This course addresses key issues in developmental biology focused on the role of stem cells and emphasizes in-depth discussion of current literature and unanswered questions. One of the Contemporary Topics in Cell Signaling modules.

Permission of the instructor. Required preparation, coursework in genetics, cell biology, and molecular biology.

BIOC/PHCO 745 – Intercellular Signaling in Development and Disease*

(1 cr hr)
T/Th @ 2:00 – 3:15 pm (January 11 – February 8)
Location TBA
Course Instructor Dr. Yuliya Pylayeva-Gupta

This graduate-level course concentrates on up-to-date views of intercellular signal processing, with emphasis on signal transduction mechanisms as they relate to cellular/physiological responses in both normal development and disease. Signaling mechanisms that will be discussed include autocrine, paracrine, juxtacrine signaling and cell-matrix interactions.

GNET/PHCO 749 – Practical RNA-SEQ*

(2 cr hr)
M/W/F 1:20 – 2:50 pm ( March 20 – April 28)
Location: most likely MEJ 3116
Course Instructors: Drs. Mauro Calabrese, Hemant Kelkar, Jesse Raab

This graduate-level course concentrates on up-to-date views of intercellular signal processing, with emphasis on signal transduction mechanisms as they relate to cellular/physiological responses in both normal development and disease. Signaling mechanisms that will be discussed include autocrine, paracrine, juxtacrine signaling and cell-matrix interactions.

There are no formal prerequisites required for this course and no prior experience with UNIX or the command line interface is expected.

PHCO 750 – Proteomics Methods and Applications

(1 cr hr)
M/W 1:30 – 300 pm (Januray 29 – TBA)
Location: TBA
Course Instructor: Dr. Laura Herring

This course will familiarize graduate students with the fundamental concepts of mass spectrometry-based proteomics with emphasis on its applications (expression proteomics, post-translational modification identification, and interactomics) and practical aspects of these applications, such as experimental design, sample preparation and data interpretation. This course is intended for 2nd year students and above who currently use or plan to use proteomics in their research.

Enrollment cap of 30