|
Graduate, Degree |
Defense Date |
Advisor |
Dissertation Title |
Current Position |
| Michael J. Lee, Ph.D. |
4/8/08 |
Henrik Dohlman |
"Activation of G protein signaling by a non-receptor exchange factor" |
Postdoctoral Fellow, UNC-CH |
| Amanda C. Sharko, Ph.D. |
4/1/08 |
Clyde Hodge |
"The role of metabotropic glutamate receptors and associated cell signaling pathways in the acute sedative-hypnotic effects of ethanol" |
Postdoctoral Fellow, UNC-CH |
| Mariya Chhatriwala, Ph.D. |
3/31/08 |
John Sondek |
"Defining diverse mechanisms that regulate the activity of Dbl-family guanine nucleotide exchange factors" |
Postdoctoral Fellow, UK |
| Ryan Shanks, M.S. |
3/26/08 |
Henrik Dohlman |
"GAP independent RGS action" |
Returned to UNC-CH Med School to obtain MD (is enrolled in MD/Masters program) |
| Donita Brady, Ph.D. |
3/17/08 |
Adrienne Cox |
"The transforming Rho family GTPase, Wrch-1, regulates epithelial cell morphogenesis through modulating cell junctions and actin cytoskeletal dynamics" |
Postdoctoral Fellow, UNC-CH |
| Jiyoung Cha, Ph.D. |
7/24/07 |
Channing Der |
"The role and mechanism of fibroblast growth factor receptor 2 in cellular transformation" |
Posdoctoral Fellow, UNC-CH |
| Bin Zhao, Ph.D. |
7/11/07 |
Leslie Parise |
"Regulation of cell survival by CIB1, a new modulator of
3-phosphoinositide-dependent protein kinase 1 (PDK1)" |
Returned to China
|
| Eric Wauson, Ph.D. |
7/3/07 |
Lee Graves |
"The Regulation of the Pyrimidine Biosynthetic Protein CAD by
Phosphorylation and Protein-Protein Interactions" |
Postdoctoral Fellow,
University of Southwestern Texas, Dallas, TX
|
| Matthew Higgins, Ph.D. |
7/2/07 |
Lee Graves |
"Regulation of Human Cytidine Triphosphate Synthetase 1 by
Phosphorylation and Interacting Proteins" |
Postdoctoral Fellow,
Gladstone Inst., University of California at San Francisco |
| Christopher Johnston, Ph.D. |
6/29/07 |
David Siderovski |
"Structural Insights into the Molecular Basis of
Heterotrimeric G-protein Signal Transduction" |
Postdoctoral Fellow,
Institutes of Molecular Biology and Neuroscience, University of Oregon,
Eugene, OR |
| YiXing (Emily) Zhou, Ph.D. |
6/28/07 |
Ken Harden |
"Cloning and Characterization of a Novel Phospholipase C
Isozyme, PLC-n2" |
Postdoctoral Fellow, UNC-CH |
| Mohamed Zayed, Ph.D. |
6/6/07
|
Leslie Parise |
"ClB1 Mediated Regulation of Endothelial Cells and Pathological
Angiogenesis" |
Returned to UNC-CH Med School to obtain MD (is enrolled in
MD/PHD program). |
| Rafael Rojas, Ph.D. |
5/21/07 |
John Sondek |
"Coordinating the activation of RhoA by diverse RhoGEFs: SmgGDS and
G-alpha-q-responsive Dbl family guanine nucleotide exchange factors" |
Scientist I - Emerging Technologies BRIDG,
Neurocrine Biosciences, Inc.
12790 El Camino Real,
San Diego, CA 92130 |
| James Ferguson, Ph.D. |
5/10/07 |
Cam Patterson |
"Ankyrin Repeat and SOCS Box Protein 4 (ASB4) is a Hydroxylation
Substrate of Factor Inhibiting HlF1a(FlH) and Promotes Vascular
Differentiation via an Oxygen-Dependent Mechanism" |
Returned to UNC-CH
Med School to obtain MD (is enrolled in MD/PHD program)
|
| Holly Gentry, Ph.D. |
5/3/07 |
Leslie Parise |
"Structure and Biochemical Characterization of CIB1" |
Medical
Science Writer, Education and Training Systems International, Chapel
Hill, NC |
| Jason Seifert, Ph.D. |
3/30/07 |
Ken Harden |
"Regulation of phospholipase C-epsilon by Rho and Ras Family GTPases" |
Law School |
| Breann Wolfe, Ph.D. |
3/26/07 |
JoAnn Trejo |
"Clathrin-dependent Internalization of Protease-activated
Protease-activated Receptor-1: Regulation by Ubiquitination and Epsin" |
Postdoctoral Fellow, Department of Biochemistry and Molecular
Pharmacology, Thomas Jefferson University, Philadelphia, PA. |
| Dayle Houston, Ph.D. |
3/23/07 |
Ken Harden |
"Agonist-Promoted Regulation of the P2Y1 Receptor: Quantification of
Native and Recombinant Receptors with the Novel Radioligand
[32P]MRS2500 |
Medical Writer,
PPD, Inc.,
Research Triangle Park, NC |
| Marielle Yohe, Ph.D. |
3/19/07 |
John Sondek |
"Auto-inhibition of Tim and Related Dbl-family Rho GEFs by an N-terminal
Helical Motif"; |
Returned to UNC-CH Med School to obtain MD (is enrolled
in MD/PHD program) |
| Melinda D. Willard, Ph.D. |
10/27/06 |
David Siderovski |
“Multiple Domain ‘Nexus’ Proteins in Receptor-Mediated Cell Signaling” |
Postdoctoral Fellow, UNC-CH |
| Sheritha P. Lee, Ph. D. |
6/19/06 |
Leslie Parise |
“Chronic Inflammation in Sickle Cell Disease: Potential Role of Platelets
and the Inflammatory Mediator CD40L” |
Postdoctoral Fellow, UNC-CH |
| Biljania Djukic, Ph.D. |
4/11/06 |
Ken McCarthy |
“Role of the inward rectifying K+ channel, Kir4.1, in astrocyte physiology and neuronal excitability” |
Postdoctoral Fellow, UNC-CH |
| May M. Paing, PhD |
8/25/05 |
JoAnn Trejo |
Regulation of Protease-activated Receptor 1 Signaling and Trafficking |
Postdoctoral Fellow, Howard Hughes Med. Institute, Washington University Medical School |
| Nathan Allen, MS |
7/28/05 |
Jude Samulski |
Investigation of the Potential for Adeno-Associated Virus Type 5 to Establish Latency by Integration |
MBA student at the Tepper School of Business at Carnegie Mellon University |
| Patricia Joyce Keller, PhD |
7/5/05 |
Adrienne Cox |
Characterization of the small GTPase Rac3 in signaling and transformation |
Postdoctoral Fellow, UNC-CH |
| Anurag Singh, PhD |
5/16/05 |
Channing Der |
The Role of Divergent Rho Family Members Rac1b and Rnd3 in Cellular Transformation and Oncogenesis |
Postdoctoral Fellow, Harvard Medical School |
Scott Oloff,
PhD |
4/20/05 |
Richard Mailman,
Alex Tropsha |
Development of Computer Aided Drug Discovery Methods Based on Machine Learning Techniques and Application to the Dopamine D1 Receptor |
Postdoctoral Fellow, UNC-CH |
| Vivian Choi,
PhD |
4/1/05 |
Jude Samulski |
The Involvement of DNA Replication and Repair Pathways in DNA Recombination Utilizing Viral DNA Terminal Repeat Hairpin Structures |
Postdoctoral Fellow, UNC-CH |
| Matthew Edin, PhD |
3/29/05 |
Rudy Juliano |
Role of PAK and PKA in Adhesion-Dependent ERK Activation by EGF |
Postdoctoral Fellow, NIEHS |
| Thomas Hilder, PhD |
3/18/05 |
Lee Graves |
Phosphorylase Kinase and MAP Kinase Regulation During Skeletal Muscle Apoptosis and Atrophy |
Postdoctoral Fellow, UNC-CH |
| Shannon Penland,
PhD |
3/4/05 |
Leslie Morrow |
Effects of Ethanol on Biosynthesis of GABAergic Neurosteroids |
Research Fellow, Cato Research, Ltd., Durham, NC |
| Erik Bodor,
PhD |
2/21/05 |
Ken Harden |
Purification of the Human P2Y12 Receptor: Ligand Binding, G Protein Coupling, and Regulation by RGS Proteins |
Postdoctoral Fellow, Max Planck Institute, Heidelberg, GER |
Sarah Leonard,
PhD |
11/15/04 |
Richard Mailman |
The Amygdala: A Model System for Novel Dopamine Receptor Pharmacology |
Postdoctoral Fellow, Wyeth Pharmaceuticals Neuroscience Division, Princeton, NJ |
| Todd Palmby, PhD |
7/6/04 |
Channing Der |
Components of Vav Mediated Transformation and Signal Transduction |
Postdoctoral Fellow, National Inst. of Dental and Cranofacial Research, Bethesda MD |
| Rhonda Saunders Wilder,
MS |
3/24/04 |
Adrienne Cox |
Regulation of Ect2, a Dbl family RhoGEF, by its Pleckstrin Homology (PH) domain |
Lab Research Specialist , UNC-CH |
Carolyn Coyne,
PhD |
4/30/03 |
Larry Johnson |
Characterization and Modulation of Airway Tight Junctions |
Postdoctoral Fellow, Children’s Hospital of PA, U Penn, Philadelphia, PA |
Donnie Eddins,
PhD |
11/24/03 |
Bob Rosenberg |
Regulation of alpha7 neuronal nicotinic acetylcholine receptors by extracellular divalent cations |
Postdoctoral Fellow, Dept. of Psychiatry, Duke University, Durham, NC |
| Sally A. Hunsucker,
PhD |
6/18/03 |
Beverly Mitchell |
The Role of Cytosolic 5’-Nucleotidase IA in Nucleoside Analog Metabolism |
Postdoctoral Fellow, UNC-CH Lineberger Cancer Center |
Randall Kimple,
PhD |
6/25/03 |
David Siderovski |
The Goloco Motifs of RGS12 and RGS14—Novel Regulators of G-Protein Signaling |
Medical Resident, UNC-CH |
| Mark K. Larson, PhD |
12/15/03 |
Leslie Parise |
Mechanisms and functions of glycoprotein VI-mediated Rap1 activation in platelets |
Postdoctoral Fellow, Center for Cardiovascular Sciences, Univ. Birmingham, UK |
| Aylin Ulku, PhD |
5/16/03 |
Channing Der |
RAS Regulation of Gene Expression in Ovarian Carcinogenesis |
Medical Resident, Yale Medical Center |
| Amy Brinson, PhD |
8/22/02 |
Ken Harden |
Differential Regulation of Uridine Nucleotide-activated P2Y4 and P2Y6 Receptors |
Scientific writer, IMFORM GmbH, International Clinical Research |
| Chris Herold, PhD |
8/12/02 |
Rob Nicholas |
Nucleotide Selectivities of the Human and Rat P2Y4 Receptors and Pharmacological Analysis of Chimeric Human/Rat P2Y4 Receptors |
Research Scientist, RheoGene, Norristown, PA |
| Peter Sazani, PhD |
7/26/02 |
Ryszard Kole |
The Role of Chemical Structure in the Delivery and Activity of Antisense Oligonucleotides |
Postdoctoral Fellow, Harvard Medical School, Boston MA |
| Melanie Olesky, PhD |
6/10/02 |
Rob Nicholas |
The Mechanism of Porin-mediated Antibiotic Resistance in Neisseria gonorrhoeae |
Postdoctoral Fellow, Harvard Medical School, Boston MA |
| John Lambert, PhD |
5/14/02 |
Channing Der |
Rac: Upstream Activation and Downstream Signaling |
Technology Transfer, Univ. South Florida |
| Patrick Hines, PhD |
3/22/02 |
Leslie Parise |
Intracellular Cyclic AMP Promotes Sickle RBC Aggregation and Adhesion to Laminin |
Resident, Children’s Hospital of PA, U Penn |
| Jason Kralic, PhD |
10/3/02 |
Leslie Morrow |
GABAA Receptor α1 Subunity Knockout Mice Exhibit Plasticity of Gabaergic Function and Behavior |
Scientific Manager, Schwarz Pharma, Raleigh, NC |
| Danielle Mercatante, PhD |
10/11/02 |
Ryszard Kole |
Modification of the Alternative Splicing Pattern of BCL-x pre-mRNA: Induction of Cell Death and Chemo-sensitization of Cancer Cells |
Postdoctoral Fellow, NIEHS, Research Triangle Park, NC |
| Peter Ward, PhD |
1/28/02 |
Dhiren Thakker |
Phospholipase C as a Regulator of Epithelial Tight Junction Permeability: Molecular and Cellular Mechanisms |
Research Scientist, Arena Pharmaceuticals, San Diego CA |
| Victoria Harding, PhD |
11/20/01 |
Howard Rockman |
Role of G Protein-Coupled Receptor Signaling in the Pathogenesis of Heart Failure |
Postdoctoral fellow, UCSD, La Jolla CA |
| Kevin Pruitt, PhD |
11/6/01 |
Channing Der |
Ras and Rho Regulation of the Cell Cycle and Oncogenesis |
Postdoctoral Fellow, Johns Hopkins Univ., Baltimore MD |
| Jennifer Obernier, PhD |
6/8/01 |
Fulton Crews |
The Relationship between Binge Drinking, Neurodegeneration and Cognitive Dysfunction |
Study Director, Inst. for Laboratory Animal Research, National Academy of Sciences, Washington DC |
| Terry Amiss, PhD |
4/6/01 |
Jude Samulski |
Investigation of the DNA Sequences Required for Site-specific Integration of Adeno-associate Virus Type 4 |
Research Scientist, Becton Dickinson Technologies, RTP NC |
| Julie Brittain, PhD |
10/27/00 |
Leslie Parise |
Integrin-Associated Protein is an Agonist and Adhesion Receptor on Sickle Red Blood Cells |
Postdoctoral Associate, UNC-Chapel Hill |
| Jung Weon Lee, PhD |
7/11/00 |
Rudy Juliano |
The Role of Alpha 5 Beta 1 Integrin in Intestinal Epithelial Cell Survival |
Associate Professor, Seoul National University, Korea |
| Mike Wheeler, PhD |
5/10/00 |
Ron Thurman |
Oxidative Stress and Hepatic Gene Delivery: Studies with Adenovirus and Adeno-associated Virus |
Assistant Professor, UNC-Chapel Hill |
| Erik Dahlstrand, MS |
6/28/00 |
Lee Graves |
Evidence of Unique Mitogen Activated Protein Kinase Localization to the Mitochondria |
Research Scientist, Vertex Pharmaceuticals, Cambridge MA |
| Michelle Cunningham, PhD |
3/10/00 |
Ken Harden |
Regulation of Inositol Lipid Signaling at Multiple Levels through Protein Kinase C-promoted Phosphorylation |
Patent Attorney |
