Welcome to the Pharmacology Department!

Henrik Dolman, PhD, ChairOur Graduate Program is dedicated to the training of outstanding scientists in the pharmacological sciences. 
An outstanding graduate program is a high priority of our department, and the training faculty participate fully at all levels. Our department ranks consistently in the highest levels of NIH funding for pharmacology departments nationwide and a great diversity of research areas is available to trainees. more

The Department of Pharmacology ranks #4 in the nation in NIH research funding in its field.

Our Global Science Ranking: #2 In the World in Pharmacology and Toxicology Research and Publications, according to U.S. News & World Report's Best Global Universities 2016 report.

Carolina ranked top college value for 16th time in American public higher education, according to Kiplinger’s Personal Finance! 

We welcome Henrik Dohlman, PhD, as the new Chair of the Pharmacology Department, effective October 1, 2016!

Science Highlights: This is LSD attached to a brain cell serotonin receptor

Using brilliant colors and fractals associated with LSD hallucinogenic properties, the crystal structure of LSD is displayed in a psychedelic fashion. Cover art by Annie Spikes.Bryan Roth's Lab report the first crystal structure of LSD bound to one of its molecular targets, the serotonin 5-HT2B receptor in the January 26, 2017 issue of Cell. The article was featured on the cover of the issue with art by Annie Spikes.

Postdoctoral researchers Daniel Wacker, Sheng Wang and John McCorvy are co-first authors on the paper which details precisely what the drug lysergic acid diethylamide (LSD) looks like in its active state when attached to a human serotonin receptor of a brain cell, and their first-ever crystal structure revealed a major clue for why the psychoactive effects of LSD last so long. read more...

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Science Highlights: Ganglionic GFAP+ glial Gq-GPCR signaling enhances heart functions in vivo

Alison Xiaoqiao Xie
Alison Xiaoqiao Xie, Research Assistant Professor in Ken McCarthy's lab, and first author on the paper
The McCarthy Lab published a paper in JCI Insights describing how a forgotten group of cells located in the sympathetic ganglia, called satellite glial cells, have profound influences on sympathetic activity. The Gq-GPCR activation of these glial cells leads to robust and long-lasting sympathetic activation, likely via their interactions with neurons in the same ganglia. Their study showed that activating the Gq-GPCR signaling in these cells increases heart rate and functions, serving as the first report on the function of these glial cells in the sympathetic ganglia. This is also significant to glial biology given that this is the first demonstration that  there is active and physiologically relevant signaling between these glia and nearby neurons. Alison Xiaoqiao Xie, Research Assistant Professor, is first author on the paper. read more...
Orrin Stone Receives NIH ImPACT fellowship!

Orrin Stone ImPACT AwardCongratulations to Orrin Stone, a graduate student in the Hahn Lab, for receiving an NIH ImPACT fellowship, enabling him to intern at a Research Triangle pharmaceutical company.

Upcoming Events
Seminar presented by Dr. Christine Eischen, Thomas Jefferson Univ. Mar 28, 2017 04:00 PM - 05:00 PM — 1131 Bioinformatics Auditorium
Seminar presented by Dr. James McNamara, Duke Neuro Apr 04, 2017 04:00 PM - 05:00 PM — 1131 Bioinformatics Auditorium
Student Research Seminar Series presents: Patrick McCarter and Andrew Crowther Apr 07, 2017 12:00 PM - 01:00 PM — 4007 GMB
Seminar presented by Dr. Oliver Bell, Inst for Molecular Biotech, Austria Apr 11, 2017 04:00 PM - 05:00 PM — 1131 Bioinformatics Auditorium
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