Welcome to the Pharmacology Department!

Henrik Dolman, PhD, ChairOur Graduate Program is dedicated to the training of outstanding scientists in the pharmacological sciences. 
An outstanding graduate program is a high priority of our department, and the training faculty participate fully at all levels. Our department ranks consistently in the highest levels of NIH funding for pharmacology departments nationwide and a great diversity of research areas is available to trainees. more

The Department of Pharmacology ranks #4 in the nation in NIH research funding in its field.

Our Global Science Ranking: #2 In the World in Pharmacology and Toxicology Research and Publications, according to U.S. News & World Report's Best Global Universities 2016 report.

Carolina ranked top college value for 16th time in American public higher education, according to Kiplinger’s Personal Finance! 

We welcome Henrik Dohlman, PhD, as the new Chair of the Pharmacology Department, effective October 1, 2016!

Science Highlights: This is LSD attached to a brain cell serotonin receptor

Using brilliant colors and fractals associated with LSD hallucinogenic properties, the crystal structure of LSD is displayed in a psychedelic fashion. Cover art by Annie Spikes.Bryan Roth's Lab report the first crystal structure of LSD bound to one of its molecular targets, the serotonin 5-HT2B receptor in the January 26, 2017 issue of Cell. The article was featured on the cover of the issue with art by Annie Spikes.

Postdoctoral researchers Daniel Wacker, Sheng Wang and John McCorvy are co-first authors on the paper which details precisely what the drug lysergic acid diethylamide (LSD) looks like in its active state when attached to a human serotonin receptor of a brain cell, and their first-ever crystal structure revealed a major clue for why the psychoactive effects of LSD last so long. read more...

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Science Highlights: Ganglionic GFAP+ glial Gq-GPCR signaling enhances heart functions in vivo

Alison Xiaoqiao Xie
Alison Xiaoqiao Xie, Research Assistant Professor in Ken McCarthy's lab, and first author on the paper
The McCarthy Lab published a paper in JCI Insights describing how a forgotten group of cells located in the sympathetic ganglia, called satellite glial cells, have profound influences on sympathetic activity. The Gq-GPCR activation of these glial cells leads to robust and long-lasting sympathetic activation, likely via their interactions with neurons in the same ganglia. Their study showed that activating the Gq-GPCR signaling in these cells increases heart rate and functions, serving as the first report on the function of these glial cells in the sympathetic ganglia. This is also significant to glial biology given that this is the first demonstration that  there is active and physiologically relevant signaling between these glia and nearby neurons. Alison Xiaoqiao Xie, Research Assistant Professor, is first author on the paper. read more...
Discover With Us This Summer!


We are less than a week away from the application deadline for our 32nd year of our Carolina Summer Fellowship Program!

Undergraduate Students are encouraged to apply now for this 10-week summer experience that includes hands on research, professional and social development. A stipend, on-campus housing and a food allowance are offered to each student selected for the program. Get your application in now! Learn more..

Upcoming Events
Suzanne Minton "From Lab to Life" Seminar Mar 01, 2017 11:00 AM - 11:45 AM — 4007 GMB
Seminar presented by Dr. Erin S. Calipari, Icahn School of Medicine at Mt. Sinai Mar 07, 2017 04:00 PM - 05:00 PM — 1131 Bioinformatics Auditorium
Student Research Seminar Series presents: Ian MacDonald and Angela Lovett Mar 10, 2017 12:00 PM - 01:00 PM — 4007 GMB
Seminar presented by Dr. Joel Neilson, Baylor College of Medicine Mar 14, 2017 04:00 PM - 05:00 PM — 1131 Bioinformatics Auditorium
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