Welcome to the Pharmacology Department!

Henrik Dolman, PhD, ChairOur Graduate Program is dedicated to the training of outstanding scientists in the pharmacological sciences. 
An outstanding graduate program is a high priority of our department, and the training faculty participate fully at all levels. Our department ranks consistently in the highest levels of NIH funding for pharmacology departments nationwide and a great diversity of research areas is available to trainees. more

The Department of Pharmacology ranks #4 in the nation in NIH research funding in its field.

Our Global Science Ranking: #2 In the World in Pharmacology and Toxicology Research and Publications, according to U.S. News & World Report's Best Global Universities 2016 report.

Carolina ranked top college value for 16th time in American public higher education, according to Kiplinger’s Personal Finance! 

Roth Lab Scientists Take a Big Step toward Building a Better Opioid

Kappa Opioid Receptor in the Active StateFor the first time, scientists at the University of North Carolina School of Medicine and collaborators solved the crystal structure of the activated kappa opioid receptor bound to a morphine derivative. The lead researchers, Pharmacology Distinguished Professor, Bryan Roth, MD, PhD, and postdocs Tao Che, PhD and Daniel Wacker, PhD, then created a new drug-like compound that activates only that receptor, a key step in the development of better pain medications.

The research, published in the journal Cell, shows a route toward creating opioids that relieve pain without causing the severe side effects at the heart of the opioid epidemic. read more...

WRAL News Highlights Roth Lab's New Drug-Like Compound That Could Treat Pain Without Addiction

WRAL News Highlights Roth Lab Opioid ResearchWRAL News highlights Bryan Roth's development of a new drug-like compound that targets a kappa opioid receptor in the brain that can relieve pain without the negative side effect of addiction. This discovery creates a pathway for the development of better pain medicines.

Watch the WRAL News video here...
Read more on Wral Tech Wire...

UNC School of Medicine to Launch Computational Medicine Program

Timothy Elston, PhDThe School of Medicine will launch a new Computational Medicine Program, which aims to channel UNC’s strength in computational biology, the basic sciences and clinical research, towards the goal of making significant advances in clinical care for patients. 

Led by Timothy Elston, PhD, and Chuck Perou, PhD, the university-wide program aims to advance personalized medicine for patients. read more...

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State

Jean Cook, PhDA special cluster of proteins that helps unwind DNA during cell division plays a key role in keeping stem cells in their immature state, according to a new study by UNC School of Medicine researchers. The study, published by Jean Cook's lab in the online journal eLife, illuminates the basic biology of stem cells, and suggests a new molecular handle for controlling them. read more...

Congratulations to Pharmacology 2017 Award Winners!
  • Samantha Bevill - 2017 Pharmacology Student Scholar
  • Raquel Martinez Chacin - 2017 Pharmacology Student Scholar
  • Tao Che - 2017 Post Doc Scholar Award
  • Reid Olsen - 2017 Thomas Collum Butler Award
  • Patty Holloway - 2017 Administrative Staff Excellence Award
  • Victor Perez - 2017 Administrative Staff Excellence Award
  • Karim Gilbert - 2017 Research Staff Excellence Award
All awards come with a check for $1000. In addition to this the Thomas Collum Butler Awardee receives a year of research funding support. Congratulations to all!

Awardees receiving their award from Dr. Henrik Dohlman, Pharmacology Chair, are pictured below (L to R top row): Samantha Bevill, Raquel Martinez Chacin and Tao Che; (L to R bottom row): Reid Olsen, Patty Holloway and Karim Gilbert.  (Click for larger view.) 
Samantha Bevill Receiving AwardRaquel Martinez Chacin Receiving AwardTao Che Receiving Award
Reid Olsen Receiving Award Patty Holloway Receiving Award Karim Gilbert Receiving Award

More pics on Facebook!

Discover With Us This Summer!

Accepting Applications for our 2018 Carolina Fellowship Summer Program starting Jan. 1, through Feb. 28, 2018!

Undergraduate Students are encouraged to apply for this 10-week summer experience that includes hands on research, professional and social development. A stipend, on-campus housing and a food allowance are offered to each student selected for the program.  Applications are open January 1 to February 28, 2018.  Learn more...

Ten BBSP Students Join Pharmacology Graduate Program!

New Graduate Students Join Pharmacology in 2017

Please join us in welcoming our new Pharmacology graduate students, who are pictured at right at MayFest! 2017.

get to know them...

Song Lab Publishes Cover Paper in Cell Stem Cell

On the cover: In this issue, Bao et al. (604–617) show that long-range GABAergic projections from medial septum (MS) are necessary and sufficient for regulating neurogenesis through dentate local PV interneurons. The cover image is an artistic modification of the MS GABAergic projections acquired from Micro-Optical Sectioning Tomography (MOST) by Dr. Hui Gong from HUST. Flying birds allude to messengers sending GABA transmitter to the neurogenic niche. The lake and forest pictured below represent local PV interneurons nourishing neural stem cells. Cover designed by Hechen Bao and Mengting Dai.Congratulations to the Song lab for publishing the cover paper for the November 2, 2017 issue of Cell Stem Cell! The paper is titled, "Long-Range GABAergic Inputs Regulate Neural Stem Cell Quiescence and Control Adult Hippocampal Neurogenesis"!  The researchers identified a neurogenesis-controlling brain circuit that runs from near the front of the brain back to the hippocampus, a learning- and memory-related structure. The hippocampus is one of the major sites of neurogenesis in the adult human brain, and the circuit that Song’s team has identified regulates this neuron-producing process. read more...

NIH gives $8.7M grant to the Bowles Alcohol Research Center

Fulton Crews, PhDCongratulations to Pharmacology faculty members Fulton Crews, Tom Kash, Clyde Hodge, Leslie Morrow, Melissa Herman and Zoe McElligott for receiving an $8.7 million 5-year grant renewal from the NIH for the Bowles Alcohol Research Center! read more...

A Microscope Maker

Wesley LegantCongratulations to Wesley Legant, PhD, assistant professor in Pharmacology, who is highlighted in a Nature technology feature, "The Microscope Makers." The feature article describes his and fellow do-it-yourself scientists' approach that lead to the development of light sheet microscopy for live cell imaging.

"...when the right tool for the job doesn’t exist, make it."

read the full article on Nature...

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Upcoming Events
*POSTPONED* Dr. Reid Townsend, WashU Presents Jan 23, 2018 04:00 PM - 05:00 PM — 1131 Bioinformatics Auditorium
Dr. Yue Yang, WashU Presents Jan 25, 2018 04:00 PM - 05:00 PM — 1131 Bioinformatics Auditorium
Dr. Dehau Pei, Ohio State University Presents Jan 30, 2018 04:00 PM - 05:00 PM — 1131 Bioinformatics Auditorium
Dr. Hugo Tejeda, NIH/Nat'l Inst on Drug Abuse Presents Feb 13, 2018 04:00 PM - 05:00 PM — 1131 Bioinformatics Auditorium
Dr. Meaghan Creed, Univ of Maryland, SOM Presents Feb 20, 2018 04:00 PM - 05:00 PM — 1131 Bioinformatics Auditorium
Dr. Janine Kwapis, UC Irvine Presents Feb 27, 2018 04:00 PM - 05:00 PM — 1131 Bioinformatics Auditorium
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