Timothy Elston

Tim Elston


Director, Graduate Program in Bioinformatics and Computational Biology

Department of Pharmacology

Ph.D., Physics
Georgia Institute of Tecnology, Atlanta, GA

Biosketch [.pdf]

Elston Lab Website
Bioinformatics and Computational Biology Program

Contact Information  ->>

Research Interests

  • Signal Transduction
  • Noise in Gene Expression
  • Airway Surface Volume Regulation
  • Motor Proteins

Research Synopsis

My lab integrates computational approaches, including mathematical modeling and quantitative image analysis, with experimental investigations to understand complex cellular behavior. Current projects in the lab focus on cell fate decisions, polarity establishment and gradient sensing. The primary model system we use to study these cellular functions is the yeast Saccharomyces cerevisiae. Our investigations combine microfluidic technology with live-cell microscopy to observe cellular behavior in well-controlled environments. This experimental platform provides a powerful system for developing and validating predictive models of cellular function. My lab also is involved in multiple collaborative projects to investigate these fundamental cellular processes in physiological contexts and their dysregulation in human disease.


Click here to view full list of published works (NCBI bibliography). 

Contact Information

Office Location:
4092 Genetic Medicine

Mailing Address:
CB # 7365
UNC-CH School of Medicine
Chapel Hill, NC 27599-7365

Office Phone: 919-843-7670
Fax: 919-966-5640



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