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Researchers find new approach to treat drug-resistant HER2-positive breast cancer

Researchers find new approach to treat drug-resistant HER2-positive breast cancer

Using human cancer cell lines, UNC scientists identified various ways that HER2-positive breast cancer tumors resist therapy, and they discovered a potential combination therapy to overcome multiple mechanisms of resistance and kill cancer cells.

Researchers find new approach to treat drug-resistant HER2-positive breast cancer - Read More…

Bryan Roth Cited in Science Signaling's Best Breakthroughs in Signaling in 2014

Bryan Roth and collaborator Raymond Stevens' Nature paper on "Molecular control of δ-opioid receptor signalling" was selected as one of the Best Breakthroughs in Signaling in 2014 in the Jan. 6 issue of Science Signaling. Gustavo Fenalti was first author on the paper.

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Mauro Calabrese Receives March of Dimes Basil O’Connor Scholar Research Award

Mauro Calabrese Receives March of Dimes Basil O’Connor Scholar Research Award

Congratulations to Dr. Mauro Calabrese, Assistant Professor of Pharmacology, who has received the 2014 Basil O’Connor Scholar Research Award from the March of Dimes Foundation.

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Roth’s novel research technique, DREADDs, lands him on Top 10 List

Roth’s novel research technique, DREADDs, lands him on Top 10 List

The National Institute of Mental Health director Tom Insel recognized Byran L. Roth, MD, PhD, for his innovative research tool.

Roth’s novel research technique, DREADDs, lands him on Top 10 List - Read More…

Graduate Student Orrin Stone Highlighted in Vital Signs Article: "Platform for Proteins"

Graduate Student Orrin Stone Highlighted in Vital Signs Article: "Platform for Proteins"

Graduate student Orrin Stone is creating molecular tools to pinpoint how and when cellular pathways trigger cell movement – or, in cancer, metastasis.

Graduate Student Orrin Stone Highlighted in Vital Signs Article: "Platform for Proteins" - Read More…

Joseph DeSimone elected to all three branches of the National Academies

Joseph DeSimone elected to all three branches of the National Academies

Joseph DeSimone, PhD, the Chancellor’s Eminent Professor of Chemistry and a joint Professor in the Department of Pharmacology, has been elected to the Institute of Medicine, one of the highest honors in the fields of health and medicine. This election represents the third time Desimone has been elected to a U.S. National Academy.

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Bryan Roth Elected to Institute of Medicine

Bryan Roth Elected to Institute of Medicine

Roth’s research to create innovative tools for neuroscientists and discover potential targets for therapeutics has earned him one of the highest honors in the field of medicine.

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UNC researchers receive $2.85-million NIH BRAIN Initiative grant

UNC researchers receive $2.85-million NIH BRAIN Initiative grant

Led by Bryan L. Roth, MD, PhD, three UNC labs will develop the next generation neuroscience tool-kit to accelerate novel treatments for neuropsychiatric and a host of other diseases. ~by Mark Derewicz

UNC researchers receive $2.85-million NIH BRAIN Initiative grant - Read More…