Using a new ‘chemogenetic’ technique invented at UNC, scientists turn neurons ‘on’ and ‘off’ to demonstrate how brain circuits control behavior in mice. This unique tool – the first to result from the NIH BRAIN Initiative – will help scientists understand how to modulate neurons to more effectively treat diseases.
Dr. Mike Miley is co-PI, along with Dr. TinChung Leung of UNC State, on one of six three-year grants funded by the University of North Carolina General Administration to support game-changing faculty research in areas of strategic importance to the state.
Using human cancer cell lines, UNC scientists identified various ways that HER2-positive breast cancer tumors resist therapy, and they discovered a potential combination therapy to overcome multiple mechanisms of resistance and kill cancer cells.
Bryan Roth and collaborator Raymond Stevens' Nature paper on "Molecular control of δ-opioid receptor signalling" was selected as one of the Best Breakthroughs in Signaling in 2014 in the Jan. 6 issue of Science Signaling. Gustavo Fenalti was first author on the paper.
Congratulations to Dr. Mauro Calabrese, Assistant Professor of Pharmacology, who has received the 2014 Basil O’Connor Scholar Research Award from the March of Dimes Foundation.
Two Pharmacology professors along with four other UNC professors elected Fellows of the AAAS.
The National Institute of Mental Health director Tom Insel recognized Byran L. Roth, MD, PhD, for his innovative research tool.
Graduate student Orrin Stone is creating molecular tools to pinpoint how and when cellular pathways trigger cell movement – or, in cancer, metastasis.
UNC Pharmacology & Toxicology Ranked #3 in the World by U.S. News & World Report
Joseph DeSimone, PhD, the Chancellor’s Eminent Professor of Chemistry and a joint Professor in the Department of Pharmacology, has been elected to the Institute of Medicine, one of the highest honors in the fields of health and medicine. This election represents the third time Desimone has been elected to a U.S. National Academy.
Roth’s research to create innovative tools for neuroscientists and discover potential targets for therapeutics has earned him one of the highest honors in the field of medicine.