CSFP Alumni

Summer Undergraduate Research Program

2016

Wendy Klein, George Mason University, BS/Chemistry with Biochemistry concentration, lab of Dr. Rob Nicholas,  “Cross-Complementation of Bifunctional Penicillin-Binding Proteins in Neisseria gonorrhoeae and Escherichia coli”

Brandon Koo, Rensselaer Polytechnic Institute, BS/Biology,  lab of Dr. Lee Graves, “Identifying Binding Partners of Oncogenic Kinase MELK" 

Christina Kresser, University of North Carolina at Chapel Hill, BS/Biology and Chemistry, lab of Dr. Channing Der, “Probing KRAS mutant-specific vulnerabilities at Gly12 for novel pancreatic therapies”

Maria Miggs, University of North Carolina at Chapel Hill, BS/Biology, lab of Dr. Mauro Calabrese, “Identifying Xist cofactors required in the initiation of X-Chromosome Inactivation"                               

Tim Qi, University of North Carolina at Chapel Hill, BS/Biology BA/Chemistry, lab of Dr. Klaus Hahn, “Creation of non-perturbing biosensors to report Rac1 activity”

Ami Shiddapur, University of North Carolina at Chapel Hill, BS/Biology, lab of Tom Kash, "Behavioral effects of activation of nociceptin modulated circuits in the CeA to NTS pathway"

Daniel Zeitouni, University of North Carolina at Chapel Hill, BSPH in Nutritional biochemistry, lab of Dr. Channing Der, "Determining the mechanistic basis underlying the effect of chloroquine in combination with an ERK inhibitor"

2015

Sainath Asokan, University of North Carolina at Chapel Hill, Biostatistics/Public Health, lab of Dr. Nigel Mackman, “Role of PAR-1 signaling in the immune response to Coxsackie B3 virus-induced myocarditis”

Jennifer Jensen, University of North Carolina at Chapel Hill, Biology and Psychology, lab of Dr. Tom Kash, “The Effects of Binge Eating: An intermittent access animal model”

David Reich, Brown University, Biochemistry and Molecular Biology, lab of Dr. Ken McCarthy, “Glia -Neuron Interaction in Sympathetic Ganglia” 

Eric West, Lafayette College, Chemistry, lab of Dr. Rob Nicholas, “Role of the Thromboxane Receptor in Platelet Activation”

2014

Cayce Dorrier, University of North Carolina at Chapel Hill, Biochemistry, lab of Dr. Tom Kash, “Genetic manipulation of 5-HT1A receptors in the extended amygdala”

Colin McDowell, University of North Carolina at Chapel Hill, Chemistry, lab of Dr. Rob Nicholas, “Resistance Mechanisms in Neisseria gonorrhoeae

Chengyu (Laura) Weng, University of North Carolina at Chapel Hill, Chemistry, lab of Dr. Alex Duncan,“Role of Neisseria Gonorrhoeae Lytic Transglycosylases in Mediating Resistance to Host Antimicrobial Responses”

Raymond Zhang, Wheaton College, Biochemistry, lab of Dr. Lee Graves, “The Regulation of BIRC6 in Drug-Resistant Chronic Myeloid Leukemia”

2013

Raúl Doyle, North Carolina State University, Microbiology, lab of Dr. Rob Nicholas, “Regulation of the MtrCDE Efflux pump by the Gonococcal efflux pump gene Regulator (GepR)”

Jennifer Frevert, Duke University, Chemistry, lab of Dr. Tom Kash, “Evaluation of a new method for lesioning inhibitory neurons”

Jakovin Lee, University of North Carolina at Chapel Hill, Biology and Chemistry, lab of Dr. Ken McCarthy, “Investigating the Role of Gq Signaling in the Regulation of the Cardiovascular System” 

Kinsey Qi, Amherst College, Biology, lab of Dr. Rob Nicholas, “Identification of the PDZ protein and associated kinase involved in internalization of the P2Y1 receptor”

Alex Sabol, Virginia Tech, Chemical Engineering, lab of Dr. Lee Graves, “Investigation into EZH2 Inhibitors and their Impact on FLT3 in Acute Myeloid Leukemia” 

2012

Brian Chen, UNC-Chapel Hill, Biomedical Engineering/Computer Science, lab of Dr. Robert Nicholas, “Interrogating the role of oxidative stress in the action of bactericidal antiobiotics in Neisseria Gonorrhoeae

Yunxiang Dai, St. Olaf College, Biology and Chemistry, lab of Dr. Zefeng Wang, “Exploring the Space of the Specific RNA Binding Sequence of the PUF Domain” 

Alexa Hendricks, Lehigh University, Biology, lab of Dr. Andrea Nackley, “Linking Genetic Variability of MOR-1K to Opioid Induced Hyperalgesia in Mice”

Lauren Jones, UNC-Chapel Hill, Biology and Spanish, lab of Dr. Lee Graves, “RSK-y Endeavor: An Investigation of the Ribosomal S6 Kinase and the inhibitor BI-D1870”

2011 

Adam Buckholz, UNC-Chapel Hill, Biology, lab of Dr. Ken Harden, “Investigating G Protein Interaction with the Canonical Arabidopsis Phospholipase C”

John Runge, Trinity Univ., History, lab of Dr. Gary Johnson, “AZD6244 and Sorafenib Combination Therapies in Triple Negative Breast Cancer Cells”

Jennifer Tran, UNC-Chapel Hill, Biology, lab of Dr. Channing Der, “Localization and activity of Ect2 RhoGEF in Colorectal Cancer” 

Elizabeth Wood, Furman University, Chemistry, lab of Dr. Angelique Whitehurst, “Elucidating the functional role of TRIM69 in chemoresistance” 

2010

Susie Choi, UNC-Chapel, Chemistry, lab of Dr. Rob Nicholas, “The Importance of the SRAT Motif in the C-Terminal Tail of the P2Y1 Receptor in Agonist-Promoted Internalization in HEK Cells”

Derek Franklin, UNC-Chapel Hill, Chemistry, lab of Dr. Ken Harden, “Development of an Assay for invivo GPCR Stimulated PLC-β3 Activity”

Laurel Oldach, Reed College, Biology, lab of Dr. Alex Duncan, “Activation of the NLRP3 Inflammasome by Neisseria gonorrhoeae Porin B”

Connie Qui, Columbia University, Biomedical Engineering, lab of Dr. David Siderovski, “The Role of Rho GTPases in Entamoeba histolytica G Protein Signaling” 

Edina Wang, UNC-CH, Biology, lab of Dr. Andrea Nackley, “Characterizing MOR-1K Expression Patterns in Pain-relevant Mouse Tissues”

2009

Lauren Burianek, UNC-Chapel Hill, Chemistry, lab of Dr. Ken Harden, “PLCγ2 augments RhoGpromoted inositol lipid hydrolysis” 

Leanna Gentry, UNC-Chapel Hill, Chemistry, lab of Dr. Gary Johnson, “Characterization of Phosphorylated MEKK2 Using Mass Spectrometry”

2008

Amanda Blackwelder, UNC-Chapel Hill, Chemistry, lab of Dr. Lee Graves, “Investigating the Nuclear Localization of Transglutaminase 2” 

Eric Gardner, University of Pittsburgh, School of Pharmacy, PharmD, lab of Dr. Robert Nicholas, “Role of Caveolin-1 in P2Y2 Receptor Signaling”

Robin Muller, UNC-Chapel Hill, Chemistry-Biochemistry, lab of Dr. David Siderovski, “Discovery of a Gα/RGS pair in Entamoeba histolytica

Alan Nguyen, Case Western Reserve University, Biomedical Engineering, lab of Dr. Klaus Hahn, “New bright probes to sense endogenous protein conformational changes”

2007

Justin Brewster, McGill University, Biochemistry, lab of Dr. Henrik Dohlman, “Identifying Components Involved in the Graded-to-Binary Switch in the Yeast Pheromone Response Pathway”

Christine Bruckner, Grinnell College, Biology, lab of Dr. Ken Harden, “P2Y1 Receptor Desensitization”

Stephanie Grecco, Univ. of Rhode Island, Psychology, lab of Dr. Fulton Crews, “The effect of cytokine production & neuroinflammation by endotoxin following ethanol exposure”

Ben Otopalik, Carleton College, Cognitive Science. “What are the effects of the L9’T mutation on conformational changes in nicotinic receptors?”

Vanessa Richards, Oberlin College, Neuroscience. “Influence of Electrostatics on Cysteine Modification in Nicotinic Acetylcholine Receptors”

Kate White, University of Illinois, Integrative Biology, lab of Dr. Robert Nicholas, “Examination of P2Y6 receptor targeting signals in MDCK epithelial cells”

Martin Whittle, Univ. of Puget Sound, Chemistry, lab of Dr. Lee Graves, “Phosphorylation of Cytidine Triphosphate Synthetase 1”

2006

Julie R. Adkins, Michigan State University, Biochemistry & Molecular Biology, lab of Dr. Robert Nicholas, “Internalization of P2Y1 receptors in MDCK cells” 

Alex Berger, University of North Carolina-Chapel Hill, Biology, lab of Dr. Adrienne Cox, “Characterization of the protein substrates for protein tyrosine phosphatase PRL-3”

Dustin E. Bosch, University of North Dakota, Premed/Chemistry, lab of Dr. Kendall Harden, “Activation of PLC-γ2 by Rac GTPases”

Rachel Currin, University of North Carolina-Chapel Hill, Biology, lab of Dr. Channing Der, “Steps to uncovering the molecular basis of human, pathological angiogenesis: Determining GTPase specificity of the RhoGAP RICH2/TEM28”

Robert Marriott, III, Dickinson College, Biology, lab of Dr. Gary L. Johnson, “Ligation-independent cloning of PB1 (Phox/Bem1p) domain in T7 promoter-based vectors and high-yield production of PB1 domain recombinant proteins” 

Amanda Mason, Harvard University, Biology, lab of Dr. Adrienne Cox, “Identification of Guanine  Nucleotide Exchange Factors (GEFs) regulated by PRL-3 to promote invasion and metastasis” 

2005

Nicholas Bessman, Iowa State University, Biochemistry, lab of Dr. Kendall Harden, “Mechanisms of Regulation of Phospholipase C Isozymes by Heterotrimeric and Ras Family G-proteins”

David Brown, UNC-Chapel Hill, Chemistry, lab of Dr. Lee M. Graves, “Building a Fluorescent-CAD Fusion Protein for Protein-Protein Interaction Studies”

Meredith Brown, MIT, Brain and Cognitive Sciences, lab of Dr. Leslie V. Parise, “Potential relationship between CIB levels & human platelet hyperactivity”

Amanda Foltz, University of Pittsburgh, Molecular Biology, lab of Dr. Robert A. Nicholas, “The Role of PilQ in Antibiotic Resistance in Neisseria gonorrhoeae

Ryan Gaffney, King’s College, Wilkes-Barre, PA, Biology and Neuroscience, lab of Dr. Fulton Crews, “The Effects of Ethanol on MCP-1, TNF-alpha, iNOS, and nNOS induction in HEC Rat Brain Slices”

2004

Joshua Albert, UNC-Chapel Hill, Chemistry, lab of Dr. Rob Nicholas, “Determination of the Apical Targeting Signal in the P2Y4 Receptor in Polarized MDCK Epithelia”

Alexa Cook, Missouri Western State College, lab of Dr. Beverly Mitchell, “Finding relationships between adenosine and AMPK signaling pathways”

Ronnie Maharaj, University of South Carolina, lab of Dr. Kendall Harden, “Characterization of Antibodies of Phospholipase C-ε”

Viviana Rosado-Ramirez, University of Puerto Rico, Mayaguez Campus, lab of Dr. Fulton Crews, “Effect of Ethanol Exposure on Hippocampal Neurogenesis

Kathryn Reinhard Cappell, University of Miami, lab of Dr. Leslie Parise, “CD40L in Sickle Cell Disease”

David Saper, University of Illinois, Urbana-Champaign, lab of Rudy Juliano, “Role of Nicharin in Regulating Cellular Movement”

2003

Desiree German, UNC-Chapel Hill, Biology, lab of Dr. Rob Nicholas, “Identification of the Basolateral Targeting Signals in P2Y12 and P2Y14 Receptors in MDCK Epithelial Cells”

Sarah Godwin, Amherst College, Biology, lab of Dr. Kendall Harden, “Gβγ Activity of the Gβ5/RGS7 Dimer” 

Kia Jackson, North Carolina A&T State University, Biology, lab of Dr. JoAnn Trejo, “Regulation of PAR2 Signaling & Trafficking” 

Adam Kimple, Michigan State University, Biology, lab of Dr. David Siderovski, “Towards small molecule inhibitors of RGS proteins”

Sarah Rogan, Wellesley College, Neuroscience, lab of Dr. Kendall Harden, “Activation of PLC–ε by Rho GTPases”

Brett Rollins, UNC-Chapel Hill, Biochemistry, lab of Dr. Channing Der, “Characterization of Pathways Required for TC21 Mediated Transformation of Human Embryonic Kidney Cells”

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