Caron Lab - Publications

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Recent Publications:

Dunworth WP, Caron KM. (2009) G Protein-Coupled Receptors as Potential Drug Targets for Lymphangiogenesis and Lymphatic Vascular Diseases.  Arterioscler Thromb Vasc Biol. 2009

Li M, Wu Y, Caron KM. (2008) Haploinsufficiency for adrenomedullin reduces pinopodes and diminishes uterine receptivity in mice. Biol Reprod. Dec;79(6):1169-75.

Fritz-Six KL, Dunworth WP, Li M, Caron KM. (2008) Adrenomedullin signaling is necessary for murine lymphatic vascular development. J Clin Invest. 118(1):40-50.

Gibbons C, Dackor R, Dunworth W, Fritz-Six K, Caron KM. (2007) Receptor activity-modifying proteins: RAMPing up adrenomedullin signaling. Mol Endocrinol. 21(4):783-96.

Li M, Yee D, Magnuson TR, Smithies O, Caron KM. (2006) Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice. J Clin Invest. 116(10):2653-62.

Dackor RT, Fritz-Six K, Dunworth WP, Gibbons CL, Smithies O, Caron KM. (2006) Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene. Mol Cell Biol. 26(7):2511-8.

Lee G, Makhanova N, Caron K, Lopez ML, Gomez RA, Smithies O, Kim HS. (2005) Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice. Endocrinology. 146(6):2650-6.

Caron KM, James LR, Lee G, Kim HS, Smithies O. (2005) Lifelong "Genetic Minipumps". Physiol Genomics. 20(2):203-9.

Caron KM, James LR, Kim HS, Knowles J, Uhlir R, Mao L, Hagaman J, Cascio W, Rockman HA and Smithies O. (2004) Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene. Proc Natl Acad Sci USA 101(9):3106-3111.

Caron KM and Smithies O. (2002) Multiple roles of adrenomedullin revealed by animal models. Micros Resch Tech 57:55-59. 2

Caron KM, James LR, Kim HS, Morham SG, Lopez MS, Gomez RA, Reudelhuber TL and Smithies O. (2002) A genetically clamped renin transgene for the induction of hypertension. Proc Natl Acad Sci USA 99(12):8248-8252.

Caron KM and Smithies O. (2001) Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. Proc Natl Acad Sci USA 98(2):615-619.

Hasegawa T, Zhao L, Caron KM, Majdic G, Suzuki T, Shizawa S, Sasano H, Parker KL. (2000) Developmental roles of the steroidogenic acute regulatory protein (StAR) as revealed by StAR knockout mice. Mol Endocrinol. 14(9):1462-71.