Faber Lab - Publications

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Pubmed:

Pubmed list

Recent Publications:

Lee YZ, Eldeniz C, Jones TB, Solander S, Huang DY, Smith JK, Faber JE, An H. (2012) Brain collateral estimation using dynamic susceptibility contrast enhancement with digital subtraction angiography validation (in review).

Lucitti JL, Mackey J, Morrison J, Haigh J, Adams R, Faber JE (2012) Formation of the collateral circulation is regulated by vascular endothelial growth factor-A and A Disintegrin and Metalloprotease Family Members 10 and 17. Circ Res (in review).

Wang S, Zhang H, Wiltshire T, Sealock R, Faber JE (2012) Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation PLoS ONE (in review).

Li F, Hagaman JR, Kim H-Y, Maeda N, Jennette JC, Faber JE, Karumanchi SA, Smithies O, Takahashi N (2011) Endothelin aggravates preeclampsia-like phenotype induced by sFlt-1 in mice lacking eNOS. J Am Soc Nephrol (in press).

Faber JE (2011) Cell therapy to augment coronary collateral growth – the promise of induced-vascular progenitor cells. Circ Res, Invited editorial (in press).

Faber JE, Zhang H, Prabhakar, RM Soares, Burnett MS, Epstein SE (2011) Aging causes collateral rarefaction and increased severity of ischemic injury in multiple tissues. Atheroscler Thromb Vasc Biol 31:1748-56.

Faber JE, Dai X, Lucitti J (2011) Genetic and environmental mechanisms controlling formation and maintenance of the native collateral circulation. In: Arteriogenesis – Molecular Regulation, Pathophysiology and Therapeutics I. E Deindl, W Schaper (eds), Shaker Verlag, Ch 1, pp 1-22.

Aitsebaomo J, Srivastava S, Zhang H, Jha S, Veleva AN, Pi X, Lockyer P, Winnick S, Faber JE*, Patterson C* (2010) Recombinant human interleukin-11 mobilizes CD34+/VEGFR2+ mononuclear cells and enhances collateral vessel growth after femoral artery ligation. Athero Thromb Vasc Biol 31:306-12. *Co-senior authors.

Wang S, Zhang H, Dai X, Sealock R, Faber JE (2010) Genetic architecture underlying variation in extent and remodeling of the collateral circulation. Circulation Res 107(4):558-68. Selected for Faculty of 1000 Biology-Exceptional. Editorial by Stephen Schwartz: http://f1000biology.com/article/id/3765959/evaluation. “This may well be the seminal paper in one of the most important mysteries in vascular biology: the mechanisms controlling collateral formation in the arterial tree…”

Chalothorn D, Faber JE (2010) Strain-dependent variation in native collateral function in mouse hindlimb. Physiol Genomics 42(3):469-79.

Zayed MA, Yuan W, Chalothorn D, Faber JE, Parise LE (2010) Tumor growth and angiogenesis Is impaired in CIB1 knockout mice. J Angiogenesis Res 2:17-27.

Zhang H, Prabhakar P, Sealock RW, Faber JE (2010) Wide genetic variation in the native pial collateral circulation is a major determinant of variation in severity of stroke. J Cerebral Blood Flow and Metabolism 30:923-934.

Chalothorn D, Faber JE (2010) Formation and maturation or the murine native cerebral collateral circulation. J Molec Cell Cardiol 49:251-259.

Dai X, Faber JE. (2010) eNOS deficiency causes collateral vessel rarefaction and impairs active-tion of a cell cycle gene network during arteriogenesis. Circ Res 106:1870-81. “Featured Article”, Journal Cover Article. Press release 5/25.

Chalothorn D, Zhang H, Smith JE, Edwards JE, Faber JE (2009) Chloride intracellular channel-4 is a determinant of native collateral formation in skeletal muscle and brain. Circulation Res 105:89-98. Journal cover article. Featured in editorial: Waltenberger J “Limits to growth of native collateral vessels. Just one mouse CLIC away from unlimited collateral perfusion?” p9-11

Cheng G, Zhang H, Yang X, Tzima E, Ewalt KL, Schimmel P, Faber JE. (2008) Mini-tyrosyl-tRNA synthetase regulates ischemic angiogenesis, leukocyte recruitment, and vascular permeability. Am J Phys Reg Integr 295(4):R1138-46.

Clayton JA, Chalothorn D, Faber JE. (2008) Vascular endothelial growth factor-A specifies formation of native collat-erals and regulates collateral growth in ischemia. Circulation Res 103(9):1027-36. Featured in editorial: Chilian WM, Pung YF. “Vascular endothelial growth factor & the collateral circulation--the story continues.”

Zhang H, Sunnarborg SW, McNaughton KK, Johns TG, Lee DC, Faber JE. (2008) Heparin-binding epidermal growth factor-like growth factor signaling in flow-induced arterial remodeling. Circ Res. 102(10):1275-85.

Zayed MA, Yuan W, Chalothorn D, Leisner T, McFadden A, Faber JE, Parise LV. (2007) CIB1 regulates endothelial cell function and ischemia-induced angiogenesis. Circulation Res 101: 1185-1193.

Chalothorn D, Clayton JA, Zhang H, Pomp D, Faber JE. (2007) Collateral density, remodeling and VEGF expression differ widely between mouse strains.  Physiol Genomics 30:179-91.  Featured as the Cover Article.