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Cell & Molecular Physiology

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CB 7545 Chapel Hill, NC 27599-7545

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Lund - Publications

Pubmed:

Pubmed list

Recent Publications:

Rigby RJ, Hunt MR, Scull BP, Helmrath MA, Lund PK. (2009) A new animal model of post-surgical inflammatory bowel disease and fibrosis: the effect of commensal microflora. Gut 58(8):1104-12

Garrison AP, Dekaney CM, VonAllmen DC, Lund PK, Henning SJ, Helmrath MA. (2009) Early but not late administration of glucagon-like peptide 2 following ileo-cecal resection augments putative intestinal stem cell expansion. Am J Physiol. 2009;296(3):G643-50.

Dekaney CM, von Allmen DC, Garrison AP, Rigby RJ, Lund PK, Henning SJ, Helmrath MA. (2008) Bacterial-Dependent Up-Regulation of Intestinal Bile Acid Binding Protein and Transport is FXR-Mediated Following Ileo-Cecal Resection. Surgery 144(2):174-81.

Zhang H, Morgan D, Cecil G, Burkholder A, Ramocki N, Scull B, Lund PK. (2008) Biochromoendoscopy: molecular imaging with capsule endoscopy for detection of polypoid lesions in the GI tract. Gastrointestinal Endoscopy 68(3):520-7. PMID:18499106.

Keku TO, Sandler RS, Simmons JG, Galanko J, Woosley JT, Proffitt M, Omofoye O, McDoom M, Lund PK. (2008) Local IGFBP-3 expression, apoptosis and risk of colorectal adenomas. Biomedical Central 8(1):143.

Robertson K, Lu Y, Qing Su, MD, Lund PK, Liu JL. (2008) A general and islet cell-enriched overexpression of IGF-I results in normal islet cell growth, hypoglycemia and significant resistance to experimental diabetes. Am J Physiol 294(5):E928-38.

Ramocki NM, Wilkins HR, Magness ST, Simmons JG, Scull BP, Lee GH, McNaughton KK, Lund PK. (2008) Insulin receptor substrate-1 deficiency promotes apoptosis in the putative intestinal crypt stem cell region, limits Apcmin/+ tumors, and regulates Sox9. Endocrinology, 149(1): p. 261-7

Rigby RJ, Simmons JG, Greenhalgh CJ, Alexander WS and Lund PK. (2007) Suppressor of cytokine signaling 3 (SOCS3) limits damage-induced crypt hyper-proliferation and inflammation-associated tumorigenesis in the colon. Oncogene, 26(33): p. 4833-41.

Dekaney CM, Fong JJ, Rigby RJ, Lund PK, Henning SJ, Helmrath MA. (2007) Expansion of intestinal stem cells associated with long-term adaptation following ileocecal resection in mice. Am J Physiol Gastrointest Liver Physiol, 293(5): p. G1013-22.

Lund PK, Rigby RJ. (2006) SOC-ing it to tumors: suppressors of cytokine signaling as tumor repressors. Gastroenterology 131(1):317-9.

Michaylira CZ, Ramocki NM, Simmons JG, Tanner CK, McNaughton KK, Woosley JT, Greenhalgh CJ, Lund PK. (2006) Haplotype insufficiency for suppressor of cytokine signaling-2 enhances intestinal growth and promotes polyp formation in growth hormone-transgenic mice. Endocrinology 47(4):1632-41.

Keku TO, Lund PK, Galanko J, Simmons JG, Woosley JT, Sandler RS. (2005) Insulin resistance, apoptosis, and colorectal adenoma risk. Cancer Epidemiol Biomarkers Prev. 14(9):2076-81.

Theiss AL, Simmons JG, Jobin C, Lund PK. (2005) Tumor necrosis factor (TNF) alpha increases collagen accumulation and proliferation in intestinal myofibroblasts via TNF receptor 2. J Biol Chem. 280(43):36099-109.

Theiss AL, Fuller CR, Simmons JG, Liu B, Sartor RB, Lund PK. (2005) Growth hormone reduces the severity of fibrosis associated with chronic intestinal inflammation. Gastroenterology. 129(1):204-19.

Theiss AL, Fruchtman S, Lund PK. (2004) Growth factors in inflammatory bowel disease: the actions and interactions of growth hormone and insulin-like growth factor-I. Inflamm Bowel Dis. 10(6):871-80.

Miller ME, Michaylira CZ, Simmons JG, Ney DM, Dahly EM, Heath JK, Lund PK. (2004) Suppressor of cytokine signaling-2: a growth hormone-inducible inhibitor of intestinal epithelial cell proliferation. Gastroenterology 127(2):570-81.

Dahly EM, Miller ME, Lund PK, Ney DM. (2004) Postreceptor resistance to exogenous growth hormone exists in the jejunal mucosa of parenterally fed rats. J Nutr. 134(3):530-7.

Lund PK. (2003) The flexible Ph.D. Gastroenterology 125(5):1301.

Greenhalgh CJ, Miller ME, Hilton DJ, Lund PK. (2002) Suppressors of cytokine signaling: Relevance to gastrointestinal function and disease. Gastroenterology. 123(6):2064-81.

Lund PK. (2002) Physiological mouse genomics. Gastroenterology. 123(2):405.

Wilkins HR, Ohneda K, Keku TO, D'Ercole AJ, Fuller CR, Williams KL, Lund PK. (2002) Reduction of spontaneous and irradiation-induced apoptosis in the small intestine of IGF-I transgenic mice. Am J Physiol. Gastrointest Liver 283(2):G457-64.