2012 IVB/MHI Joint Symposium: Dr. David A. Kass & Dr. Jeff Robbins

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Schedule of Events

9:00 Opening Remarks:

Nobuyo Maeda, PhD, Director, IVB Program

9:30 Morning Keynote Address:

David A. Kass, MD

Johns Hopkins

“Putting on the brakes: cardiac hypertrophy and NO-   cGMP signaling”

10:30 –11:30 Trainee Presentations:

Kaitlin Lenhart, Joan Taylor Laboratory UNC, Department of Pathology & Laboratory Medicine

“The Rho GTPase activating protein GRAF1 regulates skeletal myoblast differentiation and fusion”

Robert Schuck, Craig Lee Laboratory UNC, Department of Pharmaceutical Science

“Association between cytochrome P450 derived eicosanoids and vascular function in humans with established coronary artery disease”

Trisha Grevengoed, Rosalind Coleman Laboratory UNC, Department of Nutrition

“ACSL1 multi-tissue knockout mice are resistant to diet- and age-induced obesity and have altered tissue insulin sensitivity”  

Leslie Kennedy, Frank Conlon Laboratory UNC, Department of Genetics

“Characterizing a novel T-box transcriptional complex in cardiac development”

11:30 -12:15 Trainee Poster Sessions:

1^st and 2^nd Floor Foyer

12:00 -1:15 Lunch for Registered Guests

Ground Floor Foyer

12:45-1:30 Trainee Poster Sessions:

1^st and 2^nd Floor Foyer

1:30 -2:30 Trainee Presentations:

Sophie Dal-Pra, Victoria Bautch Laboratory UNC, Department of Biology

“Integrating cellular processes to form blood vessels: role of the G-protein G(alpha)i”

Chad Frasier, David Brown Laboratory East Carolina University, Department of Physiology

“Reactive oxygen species generated through NADPH oxidase during exercise trigger increased glutathione reductase expression and lead to cardio protection”

Sarah Ronnebaum, Cam Patterson Laboratory UNC, Toxicology Curriculum

“The cochaperone/E3 ubiquitin ligase CHIP protects sirtuin 6 from proteasome-mediated degradation through noncanonical ubiquitination”

Maria Aleman, Alisa Wolberg Laboratory UNC, Department of Pathology and Internal Medicine

“Fibrin (ogen)-Leukocyte interactions orchestrate venous thrombus formation and resolution”

2:30 - 2:45 Break

2:45 Afternoon Keynote Address:

Jeff Robbins, PhD

University of Cincinnati, Children’s Hospital

“Proteotoxicity: its unappreciated role in heart disease”

3:45 Announcement of Awards

4:00 Closing Remarks:

Nigel Mackman, PhD, Director, MHI