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Jennifer Gilner Pathology and Laboratory Medicine 21-214 LCCC Kirby Lab, CB# 7295 Lab Phone: 966-6767 Lab Fax: 966-8212 |
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4th Year IVB Trainee
4th Year Graduate Student
MD/PhD |
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Ph.D. Project Description:
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Genetic Approaches to Improving Hematopoietic Stem Cell Transplantation | |
Principle Investigator: |
Suzanne Kirby, MD, PhD | |
IVB Collaborator: |
Oliver Smithies, DPhil | |
Project Description: |
Transgene-induced enhancement of hemato-vascular differentiation from murine embryonic stem cells. | |
Rotations: |
Dr. Suzanne Kirby: Effects of a truncated erythropoietin receptor (tEpoR) transgene on proliferation and function of dendritic cells derived from murine bone marrow and human umbilical cord blood. | |
| Dr. Oliver Smithies: Transgene-induced enhancement of hemato-vascular differentiation from murine embryonic stem cells. | ||
Familiar Techniques: |
In Vitro Hematopoietic and Vascular Differentiation of Embryonic Stem Cells (in particular the BL-CFC (hemangioblast) assay); Hematopoietic Stem Cell Transplantation in Mice; Fluorescence Activated Cell Sorting (FACS) | |
Other Techniques used in Laboratory: |
Bone marrow harvest from mice; Isolation of Side Population (SP) Hematopoietic Stem Cells from bone marrow; Cobblestone Area Forming Cell Assay | |
Undergraduate degree: |
B.S. in Biochemistry (1999) from University of North Carolina at Chapel Hill, Chapel Hill, NC | |
Other Professional/
Graduate degree(s): |
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Awards/ Scholarships/ Grants/ Fellowships: |
Young Investigator Award, 13th Annual International Vascular Biology Meeting, June 2004, American Society for Investigative Pathology Experimental Pathologist-in-Training Predoctoral Merit Award, 2004, Gertrude B. Elion Mentored Medical Student Research Award, 2003 | |
Publications: |
Bushman, JE, Palmieri, D, Whinna, HC, and FC Church. (2000). Insight into the Mechanism of Asparaginase-Induced Depletion of Antithrombin III in Treatment of Childhood Acute Lymphoblastic Leukemia. Leukemia Research 24, p.559. | |
Personal Comments: |
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