Bradley N. Gaynes, M.D., M.P.H.

Professor and Associate Chair of Research Training and Education


 Gaynes, Brad


Phone: (919) 445-0214

Phone (Faculty Practice): (919) 445-0770


B.A., Brown University, Psychology
Post-Baccalaureate Special Student, Brown University
M.D., University of Virginia School of Medicine
Community Medicine Internship, University of Colorado Health Sciences Center
Residency, Psychiatry, University of Colorado Health Sciences Center
Fellowship, Preventive Medicine, The University of North Carolina at Chapel Hill
M.P.H., School of Public Health, Department of Epidemiology, The University of North Carolina at Chapel Hill
Robert Wood Johnson Clinical Scholar, The University of North Carolina at Chapel Hill


Summary Statement:

Dr. Gaynes works at the crossroads between clinical trials research and mental health services research (including comparative effectiveness reviews), and he focuses his efforts on mental health-primary care integration and health care delivery in real world medical practices. His expertise is in the diagnosis and management of psychiatric illness in patients not normally seen in psychiatric clinics. As a clinical trials researcher, Dr. Gaynes has participated in seminal work on primary care and HIV depression management. He has been funded through an NIMH Career Development Award (K23) from NIMH entitled, “Targeting Treatment Resistant Depression in Primary Care” and served as the Director of the UNC Regional Center for STAR*D, publishing the first direct comparison of treatment outcomes for depression in primary care vs. psychiatric care settings. Currently, Dr. Gaynes is Principal Investigator (PI) on an NIMHfunded R-34 studying the feasibility of implementing a depression care manager in HIV clinics to manage depressed HIV patients in Cameroon, and he is co-PI on an R01 assessing whether HIV outcomes in depressed HIV patients are better following randomization to measurement-based care compared to usual care. As a mental health services researcher, Dr. Gaynes has participated in systematic reviews with the Sheps Center’s Evidence-based Practice Center for the past 15 years. Most recently, he served as an expert consultant to the U.S. Preventive Services Task Force for the updates on Primary Care Depression Screening and Suicide Screening, respectively; as PI on a review of treatments for treatment-resistant depression; and as co-investigator of two reviews of PTSD.

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