Sheryl S. Moy, Ph.D.

Email: ssmoy@med.unc.edu

Office Phone: (919) 966-3082


Education:

A.B., Sociology/Psychology, Duke University

M.A., Psychology, East Carolina University

Ph.D., Psychology, University of North Carolina at Chapel Hill

 
Summary Statement:

Dr. Moy is an Associate Professor in the Department of Psychiatry at UNC, and serves as Director of the Mouse Behavioral Phenotyping Laboratory, a core facility of the Carolina Institute for Developmental Disabilities (CIDD). Dr. Moy holds a doctorate in Experimental and Biological Psychology, with a focus on behavioral pharmacology, and she completed a postdoctoral fellowship in the Brain and Development Research Center at UNC. Her area of expertise is the development and testing of rodent models for human clinical syndromes, including models for autism, schizophrenia, and other neurodevelopmental disorders. Current efforts include the behavioral, pharmacological, and neuroanatomical characterization of mouse models for repetitive behavior and restricted interests observed in autism spectrum disorders, and neonatal behavioral evaluations in a mouse model of NMDA receptor hypofunction, relevant to schizophrenia. In addition, Dr. Moy has served as an investigator or collaborator on multiple projects from CIDD investigators, including studies focused on gene x environment interactions and preclinical efficacy testing with novel therapeutic agents.

Representative Publications:

1. Ryan, B.C., Young, N.B., Crawley, J.N., Bodfish, J.W., Moy, S.S. (2010). Social deficits, stereotypy, and early emergence of repetitive behavior in the C58/J inbred mouse strain. Behavioral Brain Research 208: 178-188.

2. Moy, S.S., Nadler, J.J., Young, N.B., Nonneman, R.J., Grossman, A.W., Murphy, D.L., Crawley, J.N., Magnuson, T.R., Lauder, J.M. (2009). Social approach in genetically-engineered mouse lines relevant to autism. Genes, Brain, and Behavior 8: 129-142.

3. Moy, S.S., Nonneman, R.J., Ghashghaei, H.T., Weimer, J.M., Yokota, Y., Lee, D., Lai, C., Threadgill, D.W., Anton, E.S. (2009). Deficient NRG1-ERBB signaling alters social approach: relevance to genetic mouse models of schizophrenia. Journal of Neurodevelopmental Disorders 1(4): 302-312.

4. Moy, S.S., Nonneman, R.J., Young, N.B., Demyanenko, G.P., Maness, P.F. (2009). Impaired sociability and cognitive function in Nrcam-null mice. Behavioural Brain Research 205(1): 123-131.

5. Moy, S.S., Nadler, J.J. (2008). Advances in behavioral genetics: mouse models of autism. Molecular Psychiatry 13(1): 4-26.

6. Moy, S.S., Nadler, J.J., Poe, M.D., Nonneman, R.J., Young, N.B., Koller, B.H., Crawley, J.N., Duncan, G.E., Bodfish, J.W. (2008). Development of a mouse test for repetitive, restricted behaviors: relevance to autism. Behavioural Brain Research 188: 178-194.

7. Moy, S.S., Nadler, J.J., Young, N.B., Nonneman, R.J., Segall, S.K., Andrade, G.M., Crawley, J.N., Magnuson, T.R. (2008). Social approach and repetitive behavior in eleven inbred mouse strains. Behavioral Brain Research 191(1): 118-129.

8. Crawley JN, Chen T, Puri A, Washburn R, Sullivan TL, Hill JM, Young NB, Nadler JJ, Moy SS, Young LJ, Caldwell HK, Young WS (2007). Social approach behaviors in oxytocin knockout mice: comparison of two independent lines tested in different laboratory environments. Neuropeptides 41: 145-163.

9. Moy, S.S., Nadler, J.J., Magnuson, T.R., & Crawley, J.N. (2006). Mouse models of autism spectrum disorders: the challenge for behavioral genetics. American Journal of Medical Genetics 142(1): 40-51.

10. Moy, S.S., Perez, A., Koller, B.H., & Duncan, G.E. (2006). Amphetamine-induced disruption of prepulse inhibition in mice with reduced NMDA receptor function. Brain Research 1089(1): 186-194.