| Education:
B.A. with distinction, University
of Michigan
M.D.: University of Connecticut School
of Medicine
Internship and Residency in Psychiatry:
Yale University
Positions Held: Clinical Director,
National Institute of Mental Health;
Clinical Professor of Psychiatry,
Georgetown University School of Medicine;
Chief, Behavioral Endocrinology Branch,
NIMH
Summary
Statement:
Dr. Rubinow's research interests have focused largely on the neurobehavioral effects of gonadal steroids. He has pursued these interests by employing hormone superagonists and receptor blockers to manipulate the menstrual cycle in order to identify the central effects of gonadal steroids in isolation. He has performed similar endocrine manipulation studies in perimenopausal women and, more recently, in men. Dr. Rubinow's laboratory investigates sexual dimorphisms in neuronal and glial signal transduction as well as strain differences in behavioral sensitivity to gonadal steroids. Gene-based haplotyping of candidate genes is performed in the clinical laboratory as part of his major research effort - the attempt to identify factors accounting for the differential response across individuals to what is ostensibly the same stimulus. Dr. Rubinow has received awards for his research (e.g., A.E. Bennett Neuropsychiatric Research Foundation Award; Research Award of the Academy of Psychosomatic Medicine; Gold Medal Award of the Society of Biological Psychiatry, Mood Disorders Research Award of the American College of Psychiatrists), his clinical supervision and training (the NIH Distinguished Clinical Educator Award; NIMH Mentor of the Year 2002) and his scientific administration (USPHS Outstanding Service Medal). He is a member of a number of professional organizations, including the Endocrine Society, the American College of Neuropsychopharmacology, which he serves as Member of Executive Council, the American Neuroendocrine Society and the Society of Biological Psychiatry, which he served as President. He currently serves on the editorial boards of six journals and has authored or co-authored more than 300 scientific publications.
Representative
Publications:
| 1: |
Rubinow DR. |
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Antidepressant treatment during pregnancy: between Scylla and Charybdis.
Am J Psychiatry. 2006 Jun;163(6):954-6. |
| 2: |
Rubinow DR, Schmidt PJ. |
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Gonadal steroid regulation of mood: the lessons of premenstrual syndrome.
Front Neuroendocrinol. 2006 Jul;27(2):210-6. Epub 2006 May 2.
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| 4: |
Rubinow DR. |
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Treatment strategies after SSRI failure--good news and bad news.
N Engl J Med. 2006 Mar 23;354(12):1305-7. |
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