A study that explores three different ways to try to reduce the weight gain caused by antipsychotic medications. Children and adolescents, ages 8-19, who have gained lots of weight while taking iloperidone (Fanapt©), lurasidone (Latuda©), asenapine (Saphris©), aripiprazole (Abilify®), olanzapine (Zyprexa®), quetiapine (Seroquel®), risperidone (Risperdal®), ziprasidone (Geodon®) paliperidone (Invega®), and/or fluoxetine/olanzapine (Symbyax®) are eligible. The ways we are trying to reduce weight are healthy lifestyle guidance, change of medication and/or addition of metformin, a medication that helps the body use insulin better.
The purpose is to examine whether lurasidone (Latuda©) induces weight gain in children and adolescents ages 6-19. Participants must not have taken certain medications that are similar to Lurasidone (Latuda®) for more than 4 weeks. Similar medications include Risperdal®, Abilify®, Zyprexa®, Seroquel®, Geodon®, and Invega®.