ABIS Study

ABIS Study: Information about a Radiology department study of 3 MRIs of normal newborn infants utilizing a state of the art imaging coil which produces more defined images in 2/3 the time of a normal MRI.

ABIS Study (Advanced Brain Imaging)

What is this study about?

The purpose of this research is to learn more about the rapid and critical growth of brain development in the first years of life, and to document this growth using new advanced brain imaging equipment. This will increase our understanding of normal infant/early child brain development in this important after birth phase of life. If you participate in the study, your child will have a magnetic resonance imaging (MRI) of his/her brain three times between the ages of 2 - 4 weeks and 2 years. Scans will be performed while your child sleeps. No medicines or sedation will be used. You will also be asked medical history questions by a study coordinator or nurse.

This is a voluntary study, you will be compensated, and all information regarding you and your child’s participation in this study will be kept strictly confidential.

What does this study involve?

Your child will have a magnetic resonance imaging (MRI) of his/her brain three times between the ages of 2 - 4 weeks and 2 years depending upon which group (A or B) you will be randomized into. Scans will be performed while your child sleeps. Your child will have ear plugs (neonate) and ear phones (at ages 1 and 2) to reduce/eliminate the MRI machine noise. No medicines or sedation will be used. You will also be asked medical history questions by a study coordinator or nurse.

Will I be paid for participating?

You will receive $50 for each MRI (for a potential total of $150). You will also be reimbursed for reasonable travel and parking expenses as well.

Are there any risks?

MRI has no known risks and does not use radiation.

Why participate in this study?

You and your child’s participation in this study may benefit society by gaining new insights into our understanding of infant/early child brain development. It may also increase our knowledge into the possible causes of neurodevelopmental disorders.

Remember,

  • This is a voluntary study
  • You will be compensated
  • No medicines or sedation are involved
  • All information regarding you, and
  • your child’s participation in this study will be kept strictly confidential.

How can I learn more about joining this study?

Please contact Dianne Evans at the number below. She can explain the ABIS study in more detail and answer any questions that you may have.

Dianne Evans, MA
Program Director
Telephone: (919) 843-2389
Pager: (919) 216-1668
(866) 849-0541 (Toll Free)

Frequently Asked Questions

Will I be paid for participating?

You will receive $50 for each MRI (for a potential total of $150). You will also be reimbursed for reasonable travel and parking expenses as well.

When will I be paid for participating?

You will receive the $50 gift card at the MRI visit. Your check for mileage and/or parking will be mailed to you in 2 to 3 weeks following your MRI visit.

Will it cost me anything to be in this study?

There are no costs to subjects for participating in this research study.

Are there any risks?

MRI has no known risks and does not use radiation.

Why participate in this study?

You and your child’s participation in this study may benefit society by gaining new insights into our understanding of infant/early child brain development. It may also increase our knowledge into the possible causes of neurodevelopmental disorders.

I would like to participate in this study but I don’t drive/have a car?

Transportation can be provided if needed.

The Advanced Brain Imaging Study (ABIS) is being conducted by the Departments of Radiology, Psychiatry, and Psychology in the UNC-Chapel Hill School of Medicine.

Weili Lin, PhD
Principal Investigator

John Gilmore, MD
J. Keith Smith, MD
Guido Gerig, PhD
Hongyu An, PhD
Yasheng Chem, PhD
Robert Hamer, PhD
Research Team Members

Dianne Evans, MA
Program Director


This Study is sponsored and funded by the National Institutes of Health and has been approved by the Institutional Review Board of UNC-Chapel Hill University.

Related Links

ABIS Brochure

ABIS Brochure in Spanish