- Preclinical and clinical investigations evaluating nanotherapeutics to improve radiotherapy and chemoradiotherapy
- Development of nanoparticle therapeutics to improve systemic cancer treatment
- Utilizing nanoparticles to improve cancer immunotherapy
- Nanoparticle formulation of "forgotten"/previous failed drugs to renew their clinical translation potential
- Utilizing tissue engineering techniques to develop models of cancer metastasis
NCI/NIH Center for Cancer Nanotechnology Excellence U54
Project 1: PRINT Nanoparticles: "Calibration Quality" Nano-tools for Studying the Effect of Particle Attributes on Biodistribution, Clearance and Optimized Delivery of Therapeutics 08UCA151652A
This project aims to study the effect of size, shape and modulus on the biodistribution of nanoparticles.
R01CA178748-01 (Wang) Nanoparticle formulations of DNA repair inhibitors to improve chemoradiotherapy
This project aims to develop and evaluate nanoparticle formulations of DNA repair inhibitors to improve chemoradiotherapy for cancer.
R21CA182322 (Wang) 12/01/13 - 11/30/2016
Development of 3D organ-specific models of colorectal cancer metastasis
This project aims to develop three-dimensional in vitro models of cancer metastasis that are also organ-specific.