Sigen Wang, Ph.D.
Assistant Professor, Physics & Computing Division
- Dr. Sigen Wang
CONTACT
Phone: 919-445-5446
Fax: 919-966-7681
Email: sgwang@email.unc.edu, or sgwang88@yahoo.com
EDUCATION
PhD (1999), MSc (1993): University of Science and Technology Beijing
AREAS OF INTEREST
My research interfaces with medical physics, applied physics, materials science and microelectronics. My recent research focuses on nanoscience and nanotechnology to develop image guided micro-radiotherapy (micro-CT-RT) technology for cancer research, and single cell irradiation technology
My clinical activities include intensity-modulated radiation therapy (IMRT) quality assurance (QA), linear accelerator monthly and annual calibration and accelerator system commissioning
SELECTED PUBLICATIONS (peer-reviewed)
Sigen Wang, Ruili Wang, Paul.J. Sellin, Sha Chang. Carbon nanotube based DNA biosensor for rapid detection of anti-cancer drug of cyclophosphamide. Current Nanoscience, 5(3), 312-317, 2009
R. Peng, J. Zhang, X. Calderon-Colona, S.Wang, S. Sultana, S. Chang, J. P. Lu, O. Zhou. Stationary micro-CT scanner using a distributed multi-beam field emission x-ray source: a feasibility study. SPIE. 7258, 725847, 2009
Kun Hou, Ronald A Outlaw, Sigen Wang, Mingyao Zhu, Ronald A Quinlan, Dennis M Manos, Martin E Kordesch, Uwe Arp, Uwe, Brian C Holloway. Uniform and enhanced field emission from chromium oxide coated carbon nanosheets. Applied Physics Letters, 92, 133112, 2008
Sigen Wang, Zhijun Liu, Shabana Sultana, Eric Schreiber, Otto Zhou, Sha Chang. A novel high resolution micro-radiotherapy system for small animal irradiation for cancer research. BioFactors, 30, 265-270, 2007
A.Lohstroh, P. J. Sellin, S. G. Wang, A. W. Davies, J. M. Parkin. Mapping of polarization and detrapping effects in synthetic single crystal chemical vapor deposited diamond by ion beam induced charge imaging. Journal of Applied Physics, 101, 063711, 2007
A.Lohstroh, P. J. Sellin, S. G. Wang, A. W. Davies, J. Parkin, R. W. Martin, P. R. Edwards. Effect of dislocations on charge carrier mobility-lifetime product in synthetic single crystal diamond. Applied Physics Letters, 90, 102111, 2007
Sigen Wang, Jianjun Wang, Peter Miraldo, Mingyao Zhu, Ronald Outlaw, Kun Hou, Xin Zhao, Brian C. Holloway, Dennis Manos, Talmage Tyler, Olga Shenderova, Mark Ray, Jay Dalton, Gary McGuire. High field emission reproducibility and stability of carbon nanosheets and nanosheet-based back-gated triode emission devices. Applied Physics Letters, 89, 183103, 2006
Sigen Wang, Paul Sellin, Annika Lohstroh. Temperature dependent hole de-trapping for unprimed polycrystalline chemical vapor deposited diamond. Applied Physics Letters, 88, 023501, 2006
Sigen Wang, Paul Sellin. Pronounced hysteresis and high charge storage stability of single walled carbon nanotube-based field effect transistors. Applied Physics Letters, 87, 133117,2005
S.G. Wang, P.J. Sellin, A. Lohstroh, Qing Zhang. Performance improvement of polycrystalline diamond ultraviolet photodetectors by room-temperature plasma treatment. Applied Physics Letters, 86, 093503, 2005
S.G. Wang, Ruili Wang, P.J. Sellin, Qing Zhang. DNA biosensors based on self-assembled carbon nanotubes. Biochemical and Biophysical Research Communications, 325, 1433–1437, 2004
S.G. Wang, Q. Zhang, A. A. Bettiol. Structural imperfection distributions and alpha particle detection properties of CVD diamond film. Physics Letters A 332(5-6), 475-480, 2004
Yimin Zhao, Chunlin Zhu, Sigen Wang, J.Z. Tian, D.J. Yang, C.K. Chen, Hao Cheng, Peter Hing. Pulsed photothermal reflectance measurement of the thermal conductivity of sputtered aluminum nitride thin films. Journal of Applied Physics, 96, 4563-4568, 2004
S.G. Wang, Qing Zhang, D.J. Yang, P.J. Sellin, G.F. Zhong. Multi-walled carbon nanotube-based gas sensors for NH3 detection. Diamond and Related Materials, 13(4-8), 1327-1332, 2004
S.G. Wang, Qing Zhang, Ruili Wang,S.F. Yoon. A novel multi-walled carbon nanotube-based biosensor for glucose detection. Biochemical and Biophysical Research Communications, 311, 572-576, 2003
S.G. Wang, Qing Zhang, R.L. Wang,S.F. Yoon,J. Ahn,D.J. Yang,J.Z. Tian,J.Q. Li, Q. Zhou. Multi-walled carbon nanotubes for the immobilization of enzyme in glucose biosensors. Electrochemistry Communications, 5(9), 800-803, 2003
Da Jiang Yang, Qing Zhang, George Chen, S.F. Yoon, J.Ahn, S.G. Wang, Q. Zhou, Q. Wang, J.Q. Li. Thermal conductivity of multiwalled carbon nanotubes. Physical Review B. 66, 165440, 2002
SELECTED PRESENTATIONS
S Wang, R Peng, J Zhang, E Schreiber, O Zhou, S Chang. Recent development of a carbon nanotube field emission based x-ray micro-radiotherapy system for small animal radiotherapy. AAPM (American Association of Physicists in Medicine) Meeting, Philadelphia, USA (2010)
M Lawrence, T Cullip, L Potter, J Lian, S Wang, Z Xu, K Deschesne, S Chang. A novel method for further analysis of IMRT QA. AAPM (American Association of Physicists in Medicine ) Meeting, Philadelphia, USA (2010)
S Wang, E Schreiber, X Calderon-Colon, R Peng, S Sultana, J Zhang, O Zhou, S Chang. An image-guided micro-radiotherapy system based on carbon nanotube field emission technology for small animal irradiation for cancer research. AAPM (American Association of Physicists in Medicine) Meeting, Anaheim, USA (2009)
Sigen Wang, Xiomara Calderon, Rui Peng, Otto Zhou, Sha Chang. Carbon nanotube field emission nanotechnology based multi-pixel x-ray source for biomedical applications. 2009 MRS Fall Meeting, Boston, USA (2009)
J Lian, M Foskey, S Wang, D Shen, S Chang. In-vivo correspondence validation of a deformable image registration method. AAPM (American Association of Physicists in Medicine) Meeting, Anaheim, USA (2009)
S Wang, Z Liu, E Schreiber, S Sultana, O Zhou, S Chang. Development of carbon nanotube field emission micro-radiotherapy system for cancer research. AAPM (American Association of Physicists in Medicine) Meeting, Houston, USA (2008)
Sigen Wang, Zhijun Liu, Shabana Sultana, Eric Schreiber, Otto Zhou, Sha Chang. A novel high resolution micro-radiotherapy system for small animal irradiation for cancer research. The International Conference on Cellular and Molecular Bioengineering, Singapore (2007)
Sigen Wang, Zhijun Liu, Lei An, Otto Zhou, Sha Chang. Fabrication and characterization of individually controlled multi-pixel carbon nanotube cathode array chip for micro-RT application. 2007 MRS Fall Meeting, Boston, USA (2007).
Sigen Wang, Jianjun Wang, Peter Miraldo, Mingyao Zhu, Ron Outlaw, Kun Hou, Xin Zhao, Brian C. Holloway, Talmage Tyler, Olga Shenderova, Mark Ray, Jay Dalton, Gary McGuire. Electron field mission stability of carbon nanosheets and nanosheet-based back-gated emission devices. 2006 joint International Conference on New Diamond Science and Technology and Applied Diamond Conference (ICNDST & ADC 2006 Joint Conference), North Carolina, USA (2006).
Sigen. Wang, Paul. Sellin, Annika. Lohstroh. Pulse shape study of chemical vapor deposited diamond alpha particle detectors. 2004 MRS Fall Meeting, Boston, USA (2004).
S.G. Wang, P.J. Sellin, Q. Zhang, F.X. Lu, W.Z. Tang, A. Lohstroh. The fabrication and performance of CVD diamond-based X-ray detectors. The Fifth Pacific Rim International Conference on Advanced Materials and Processing (PRICM-5), Beijing, China (2004).
S.G. Wang, Qing Zhang, R. L. Wang, S.F. Yoon, J. Ahn, Sam Zhang. Carbon nanotubes for enzyme electrode in biosensors. The 8th IUMRS International Conference on Advanced Materials (IUMRS-ICAM 2003), Yokohama, Japan (2003).
S.G. Wang, Qing Zhang, D.J. Yang, P.J. Sellin, G.F. Zhong. Multi-walled carbon nanotube-based gas sensors for NH3 detection. 14th European Conference on Diamond, Diamond-Like Materials, Carbon Nanotubes, Nitrides and Silicon Carbide (Diamond 2003), Salzburg, Austria (2003).
SG. Wang, Q. Zhang, S.F. Yoon, J. Ahn, Q. Wang, Q. Zhou, D.J. Yang, J.Q. Li. Diamond-based alpha particle detectors with coplanar geometry. 13th European Conference on Diamond, Diamond-Like Materials, Carbon Nanotubes, Nitrides & Silicon Carbide (Diamond 2002), Spain (2002).
S.G. Wang, Q. Zhang, S. F. Yoon, J. Ahn, F.X. Lu,D. J. Yang, Q. Wang, Q. Zhou, J.Q. Li. Comparison of electron field emission characteristics of carbon nanotubes and nano-diamond films. 8th International Conference on New Diamond Science and Technology (ICNDST-8), Australia (2002).
S.G. Wang, Q. Zhang, S.F. Yoon, J. Ahn, Q. Wang, Q. Zhou, D.J. Yang. Electron field emission properties of nano- submicro- and micro-diamond films. Surface and Bulk Defects in CVD Films, VII, Belgium (2002).
S.G. Wang, Q. Zhang, S.F. Yoon, J. Ahn, B. Gan, D.J. Yang, Rusli, A.A. Bettiol, T. Osipoeicz, F. Watt. CVD diamond thin films for alpha particle detector application. 2001 MRS Fall Meeting, Boston, USA (2001)
J. Ahn, B. Gan, Q. Zhang, Rusli, S.F. Yoon, V. Ligatchev, S.G. Wang, Q.F. Huang, K. Chew, R. Meléndrez, M. Barboza-Flores. Application of CVD diamond films for UV thermoluminescence dosimeter. International Conference on Materials for Advanced Technologies (ICMAT), Singapore (2001)
BOOK CHAPTER
Sigen Wang, Otto Zhou, Sha Chang. Carbon nanotube field emission electron and x-ray technology for medical research and clinical applications, in A. V. Narlikar and Y.Y. Fu (eds): Handbook of Nanoscience and Nanotechnology. Oxford University Press, pp. 673-698, 2010
PROFESSIONAL SERVICE
IEEE Senior Member Review Panel, 2007
Reviewer for journals of “Applied Physics Letters, Biosensors and Bioelectronics, Analytica Acta, Diamond and Related Materials, Journal of Applied Physics, Journal of Nanoscience and Nanotechnology, Current Nanoscience, Thin Solid Films, Materials Research Bulletin, Optical Materials, Surface & Coating Technology, Sensors and Actuators B- Chemical, Journal of Materials Research, and Journal of Alloys and Compounds”
