Research is an important component of the Department of Surgery. There are multiple NIH-funded career development grants in the department, with junior faculty working with established senior scientist-mentors throughout the University's research community.

The Department houses multiple R01 projects and one NIH-funded training grant for surgery residents who work simultaneously with basic science and clinical mentors. Research achievements of the surgical faculty have led to increased breast conservation in patients with advanced disease treated with pre-operative adjuvant chemotherapy, correction in an animal model of a genetically determined deficit with stem cell transplants, elucidation of the mechanisms of immune dysfunction in burns, and many others.

Each surgical division has active research underway in either clinical and/or basic science programs; and the School of Medicine ranks within the top 15 of the nations' 125 medical schools in research funding from NIH.