2014 Thurston Today

A Message from the Director

Dear Friends,
Happy New Year!  The holiday season was a wonderful one, and as 2015 kicks into high gear, we are reminded of all we were thankful for last year and at the top of our list is you.  Thank you for supporting us as volunteers, as donors and with words of encouragement.  We are grateful to you for all you have done for us as this has encouraged us to work harder to give back to the community. I also want to take this opportunity to say thank you to our 100+ donors, 17 of which were faculty and staff!  Faculty and staff are denoted with an asterisk in the Donor Honor Roll.

We had a busy and exciting 2014!  Here are a few things that are highlighted in this edition of Thurston Today:

  • TARC's selection as the new home for the Osteoarthritis Action Alliance (OAAA);
  • The establishment of a new UNC Rheumatology Lupus Specialty Clinic;
  • Expansion of our clinical trials research programs;
  • Recent honors and awards and new scientific results presented in journals and at meetings;
  • Our three new faculty members;
    • Richard Loeser, MD, Herman and Louise Smith Distinguished Professor and Director of Basic and Translational Research;
    • Kelli Allen, PhD, Professor of Medicine, and;
    • Jennifer Rogers, MD, Assistant Professor of Medicine.

We have welcomed many new faces in our Division and Center since the last newsletter, including new faculty, research and administrative staff, as well as students.  Photos, short bios and areas of interest are included for each individual in our New Faces section of Thurston Today.

Finally, we say farewell and express our best wishes and gratitude to Dr. Mary Anne Dooley, Associate Professor of Medicine, who retired this spring after 23 years of devoted service to our patients, our referring physicians, the School of Medicine, and the people of North Carolina.

We hope you are still enjoying the electronic format of Thurston Today, and please explore our website further once you¹ve linked to it through the various articles and stories. You can contact us at any time to provide feedback and how we can further improve.

All of us at UNC's Thurston Arthritis Research Center and Division of Rheumatology, Allergy and Immunology hope you have a delightful 2015!

 

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TARC News

Strategic Plan Completion
The Thurston Arthritis Research Center and Division of Rheumatology, Allergy and Immunology are pleased to announce the completion of our five-year strategic plan.  We look forward to championing initiatives in our focus areas of clinical care, epidemiological research, basic and translational research, education, clinical trials and marketing and development.

 

UNC Thurston Arthritis Research Center to lead Osteoarthritis Action Alliance
The UNC Thurston Arthritis Research Center has been selected as the new home for the Osteoarthritis Action Alliance (OAAA), the Arthritis Foundation announced on May 28, 2014.

 

Sheikh and Rogers named co-directors of new UNC Rheumatology Lupus Clinic
The Division of Rheumatology, Allergy & Immunology proudly announces the establishment of the UNC Rheumatology Lupus Clinic, co-directed by Drs. Saira Sheikh and Jennifer Rogers. This clinic will provide state-of-the-art care to patients with all forms of Lupus.


Numerous faculty and staff of the Thurston Arthritis Research Center attended the OARSI World Congress in Paris, France April 24 - 27. May 07, 2014.

 

Dr. Joanne Jordan, COAMI Chair, worked with colleagues to prepare the U.S.Bone and Joint Initiative (USBJI)/COAMI annotated bibliography of guidelines and recommendations on the management of OA.

 

Dr. Mary Anne Dooley, Associate Professor of Medicine, is retiring from the UNC Health Care System at the end of February after 23 years of devoted service to our patients, our referring physicians, the UNC School of Medicine, and the people of North Carolina.

 

Allergy/Immunology clinic nurse retires
Phyllis Cameron retired this month after 21 years at UNC, 12 of which were spent as the head nurse in our Allergy/Immunology clinic. She will be dearly missed by everyone at our clinic.


 

Dr. Leigh Callahan has received a one-year grant from the Arthritis Foundation to evaluate "Camine Con Gusto," the Hispanic version of Walk With Ease program, among 200 Hispanic adults with self-reported arthritis or joint pain.

 


This summer, the Johnston County Osteoarthritis Project (JoCo) said goodbye to two of the Project’s longtime employees, both retiring after a combined 31 years of service
.

 

Welcome one of the newest members of the TARC family!
Dr. Jennifer Rogers and her husband were blessed with a beautiful, healthy baby girl. Mom, dad and baby are doing well.

NC Lupus Summit recap
The 14th Annual NC Lupus Summit was held at the Raleigh Marriott Crabtree Valley on Saturday, October 25, 2014. Patients, caregivers, and the medical community were invited for a day devoted to those affected by lupus.

Currently in OA Action Alliance News
In 2011, the Arthritis Foundation (AF) and Centers for Disease Control (CDC) mobilized a multitude of stakeholders, concerned about arthritis, to form the OA Action Alliance (OAAA). In 2014, management of OAAA activities transferred from the AF to the Thurston Arthritis Research Center (TARC) at the University of North Carolina School of Medicine.

Recent Awards and Recognition

Faculty:

Joanne M. Jordan, MD, MPH

  • Inductee, American Clinical and Climatological Association, the oldest medical society in America founded in 1884
  • American College of Rheumatology (ACR) Board of Directors

Leigh F. Callahan, PhD

  • American College of Rheumatology (ACR)/Association of Rheumatology Health Professionals (ARHP) Lifetime Achievement Award
  • Appointed Director of Osteoarthritis Action Alliance (OAAA)
  • Chronic Osteoarthritis Management Initiative (COAMI) Steering Committee
  • American College of Rheumatology (ACR) Finance Committee
  • Faculty Member, US Bone and Joint Initiative Young Investigators Program

Kelli Allen, PhD

  • Member, Addressing Disparities Review Panel for the Patient Centered Outcomes Research Institute
  • Member, Career Development Award Review Panel for Department of Veterans Affairs, Health Services Research and Developments Service
  • Chronic Osteoarthritis Management Initiative (COAMI) Steering Committee

Yvonne Golightly, PT, MS, PhD

  • Affiliate faculty member, UNC Human Movement Science Curriculum American College of Rheumatology (ACR) Quality of Care committee
  • American College of Rheumatology (ACR) Abstract Oversight Selection Subcommittee
  • 2014 UNC Junior Faculty Development Award

Maya R. Jerath, MD, PhD

  • ACCLAIM Scholar

Beth L. Jonas, MD

  • American College of Rheumatology (ACR) Committee on Training and Workforce
  • Food and Drug Administration (FDA) Arthritis Advisory Committee

Edwin H. Kim, MD, MS

  • Appointed Associate Program Director for the Allergy and Immunology Fellowship
  • Accepted into Academy of Educators
  • Accepted into the UNC Teaching Scholars program
  • Selected as an instructor in the Patient Centered Care course, part of the new UNC medical school curriculum Translational Education at Carolina

Richard F. Loeser, Jr., MD

  • Appointed Herman and Louise Smith Distinguished Professor
  • Osteoarthritis Research Society International (OARSI) Basic Science Research Award
  • Wake Forest School of Medicine Team Science Award
  • Elected Chair American College of Rheumatology (ACR) Annual Meeting Planning Committee

Amanda E. Nelson, MD, MSCR, RhMSUS

  • Certified in Musculoskeletal Ultrasound
  • 2014 UNC Junior Faculty Development Award

Jennifer L. Rogers, MD

  • Appointed Co-Director of UNC Rheumatology Lupus Clinic

Robert Roubey, MD

  • Member, Antiphospholipid Syndrome (APS) ACTION Executive Committee and Steering Committee
  • Speaker, American College of Rheumatology (ACR) Annual Meeting Curbside Consults - Ask The Experts

Saira Z. Sheikh, MD

  • Appointed Co-Director of UNC Rheumatology Lupus Clinic

Maureen Su, MD, AM

  • Jefferson Pilot Award

Teresa Tarrant, MD

  • Accepted into ACCLAIM program
  • Rheumatology Research Foundation Targeted Research Task Force
  • Rheumatology Research Foundation Scientific Advisory Council

William Yount, MD

  • University of Wisconsin Medical Alumni Citation Award

Research Teams:

Mary Altpeter - Co-investigator, Callahan and Rini Teams

  • NC Division of Aging and Adult Services Ewald W. Busse Award for impact on enhancing the health status of older North Carolinians

Diane Bresch, BSN, RN - Coordinator, Clinical Trials Team

  • Clinical Research Professional Certification


Liu Lab:

Monica Jin, PhD - Postdoctoral Fellow, Liu Lab

  • Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) Travel Award for Young Investigators


Su Lab:

Denise Allard Trout - Su Lab

  • Peter J. Dyck Award for autoimmune peripheral neuropathy presentation
  • Department of Pediatrics' Evening of Scholarship Basic Science Research Award

Lee Kyung Hong - Su Lab

  • Lineberger Scientific Retreat Basic Science poster award

 

Tarrant Lab:

Matthew Billard, PhD - Postdoctoral Researcher, Tarrant Lab

  • Received Public Policy Fellowship from American Association of Immunologists

Jaime Brozowski, MS - Graduate Research Assistant, Tarrant Lab

  • Accepted into the Howard Hughes Medical Institute (HHMI) Med-into-Grad Translational Science program

 

Fellows:

Aaron Kobernick, MD – 1st year Allergy/Immunology Fellow

  • Navajo Area Director's Award for Outstanding Group Performance
  • Presentation Selection, The Southeastern Allergy Society

Other recognition:

Rich Lotstein received the Employee Forum Peer Recognition Award.  The Employee Forum seeks to continually improve the quality of life at The University of North Carolina at Chapel Hill for its students, faculty, and employees through mutual understanding, recognition of employee contributions, and respect for the worth of the individual.

 

 

Recent Research Publications and Presentations

In 2014, 15 individuals at TARC and RAI were authors or co-authors on 80 publications in numerous medical journals.  Here are just a few to demonstrate the broad range of research interests of our faculty and fellows.  Click here for a more complete listing

 

 

 

Dr. Joanne Jordan discusses Muscles, Joints, Aches and Related Diseases
Part 1
Part 2

 

Callahan Team Presentations:

"Factors that influence adoption and implementation of the Arthritis Foundation Walk With Ease (WWE) Program in mid-size worksite settings: A Feasibility Study."
(Poster presented at the Aging Exchange, April 3, 2014.Armstrong-Brown, J., Altpeter, M., Naseer, C., Linnan, L., Callahan, L. F.)

“Associations of socioeconomic status with depressive symptoms and perceived helplessness in people with hip or knee osteoarthritis.”
(Poster presented at the Aging Exchange, April 3, 2014. Luong, M.N., Cleveland, R.J., Schoster, B., Randolph, R., Renner, J.B., Jordan, J.M. Callahan, L.F.)
 


Callahan Team Publications:
 
The role of symptoms and self-efficacy in predicting physical activity change among older adults with arthritis.
(Journal of Physical Activity and Health, 2014, 11: 528-535.Sperber NR, Hall KS, Allen KD, DeVellis BM, Lewis M, Callahan LF.)
 
Complementary and alternative medicine use in African-Americans with rheumatoid arthritis.
(Arthritis Care Res (Hoboken).2014 Feb;66(2):180-9. Doi: 10.1002/acr.22148.Tamhane A, McGwin G, Redden D, Hughes LB, Brown EE, Westfall AO, Reynolds RJ, Conn DL, Jonas BL, Smith EA, Brasington RD, Moreland LW, Bridges SL Jr, Callahan LF. )

Racial and gender differences in willingness to undergo total joint replacement:  the Johnston County Osteoarthritis Project.
(Arthritis Care Res (Hoboken). 2014 Jan 27. Doi:10.1002/acr 22295 (Epub ahead of print).Allen KD, Golightly, YM, Callahan LF, Helmick CG, Ibrahim SA, Kwoh CK, Renner JB, Jordan JM.)
 
Evaluation of active living every day in adults with arthritis.
(J Phys Act Health 2014 Feb; 11(2) 285-95 DOIN: 10.1123/jpah.2011-0317.Callahan LF, Cleveland RJ, Shreffler J, Hootman JM, Mielenz TJ, Schoser B.)
 
Feasibility and promise of a 6-week program to encourage physical activity and reduce joint symptoms among elderly breast cancer survivors on aromatase inhibitor therapy.
(Journal of Geriatric Oncology. J Geriatr Oncol 2013 Dec 28. Pii:s-1879-4068(13)00389-5. doi: 10.1016/j.jbo.2013.12.002 (Epub ahead of print).Nyrop KA, Muss HB, Hackney B, Cleveland R, Altpeter M, Callahan LF.)
 
Independent associations of childhood and current socioeconomic status with risk of self-reported doctor-diagnosed arthritis in a family-medicine cohort of North Carolinians.
(BMC Musculoskelet Disord. 2013 Nov 20; 14:327.doi:10.1186/1471-2474-14-327/ PMID: 24256740 Baldassari AR, Cleveland RJ, Callahan LF.)
 
Independent associations of Socioeconomic factors with disability and pain in adults with knee osteoarthritis.
(BMC Musculoskeletal Disorders. 2013, 14:297. doi: 10.1186/1471-2474-14-297.Cleveland RJ, Luong MN, Knight JB, Schoster B, Renner J, Jordan JM, Callahan LF.)
 
Association of self-efficacy and outcome expectations with physical activity in adults with arthritis.
(Arthritis. 2013;2013:621396/doi:1155/2013/621396 Epub 2013 Oct 24.Mielenz TJ, Kubiak-Rizzone K, Alvarez KJ, Hlavacek P, Freberger JK, Giuliani C, Mercer V, Callahan LF.)

Kelli Allen, PhD Publications:
Golightly, Y.M., Allen, K.D., Stechuchak, K.M., Coffman, C.J., Keefe, F.J. (2014) Associations of coping strategies with diary based pain variables among Caucasian and African American patients with osteoarthritis. International Journal of Behavioral Medicine. [epub ahead of print]

Nelson, A.E., Allen, K.D., Golightly, Y.M., Goode, A.P., Jordan, J.M. (2014) A systematic review of recommendations and guidelines for the management of osteoarthritis: The Chronic Osteoarthritis Management Initiative of the U.S. Bone and Joint Initiative. Seminars in Arthritis and Rheumatism, 43(6): 701-712

Voils, C. I., King, H. A., Maciejewski, M. L., Allen, K. D., Yancy Jr., W. S., & Shaffer, J. A. (2014). Approaches for informing optimal dosing of behavioral interventions. Annals of Behavioral Medicine, 48(3):392-401.

Allen, K.D., Golightly, Y.M., Callahan, L.F., Helmick, C.G., Ibrahim, S.A., Kwoh, C.K., Renner, J.B., Jordan, J.M. (2014) Racial and gender differences in willingness to undergo total joint replacement: the Johnston County Osteoarthritis Project, Arthritis Care & Research, 66(8): 1193-1202

Zullig LL, Bosworth HB, Jeffreys AS, Corsino L, Coffman C, Oddone E, Yancy W, Allen K. "The Association of Comorbid Conditions with Patient Reported Outcomes in Veterans with Hip and Knee Osteoarthritis." [in press with Clinical Rheumatology]

Murphy, L.B., Helmick, C.G., Allen, K.D., Theis, K.A., Baker, N.A., Murray, G.R., Qin, J., Hootman, J.M., Brady, T.J., Barbour, K.E. (2014) Arthritis among veterans – United States, 2011-2013. MMWR, 63(44), 999-1003.


Yvonne Golightly, PT, MS, PhD Publications:
Golightly YM, Hannan MT, Dufour AB, Renner JB, Jordan JM.  Factors associated with hallux valgus in a community-based study of adults with and without osteoarthritis.  Arthritis Care and Research.  In press.

Dore AL, Golightly YM, Mercer VS, Shi XA, Renner JB, Jordan JM, Nelson AE.  Lower Limb Osteoarthritis and the Risk of Falls in a Community-Based Longitudinal Study of Adults with and without Osteoarthritis.  Arthritis Care and Research.  In press.

Harkey M, Luc B, Golightly YM, Thomas A, Driban J, Hackney A, Pietrosimone B. Osteoarthritis-Related Biomarkers Following Anterior Cruciate Ligament Injury and Reconstruction: A Systematic Review.  Osteoarthritis and Cartilage, 2014 Sep 16. pii: S1063-4584(14)01250-3.

Golightly YM, Hannan MT, Dufour AB, Hillstrom HJ, Jordan JM.  Foot disorders associated with over-pronated and over-supinated foot function: The Johnston County Osteoarthritis Project.  Foot and Ankle International, 2014 Nov;35(11):1159-65.

Dufour AB, Casey VA, Golightly YM, Hannan MT.  Characteristics associated with hallux valgus in a population-based study of older adults: The Framingham Foot Study.  Arthritis Care and Research, 2014 Jun 25, in press.

Golightly YM, Allen KD, Stechuchak KM, Coffman CJ, Keefe FJ. Associations of coping strategies with diary based pain variables among Caucasian and African American patients with osteoarthritis.  International Journal of Behavioral Medicine, 2014 Mar 4, in press.

Allen KD, Golightly YM, Callahan LF, Helmick CG, Ibrahim SA, Kwoh CK, Renner JB, Jordan JM. Racial and gender differences in willingness to undergo total joint replacement:  the Johnston County Osteoarthritis Project. Arthritis Care and Research, 2014 Aug;66(8):1193-202.

Golightly YM, DeVellis RF, Nelson AE, Hannan MT, Lohmander LS, Renner JB, Jordan JM.  Psychometric properties of the foot and ankle outcome score in a community-based study of adults with and without osteoarthritis. Arthritis Care and Research, 2014 Mar;66(3):395-403.

Nelson AE, Smith MW, Golightly YM, Jordan JM.  “Generalized Osteoarthritis”: A systematic review.  Seminars in Arthritis and Rheumatism, 2014 Jun;43(6):713-20.

Nelson AE, Allen KD, Golightly YM, Goode AP, Jordan JM.  A systematic review of recommendations and guidelines for the management of osteoarthritis.  Seminars in Arthritis and Rheumatism, 2014 Jun;43(6):701-12.

Aslam I, Perjar I, Shi XA, Renner JB, Kraus VB, Golightly YM, Jordan JM, Nelson AE.  Associations between biomarkers of joint metabolism, hand osteoarthritis, and hand pain and function: The Johnston County Osteoarthritis Project.  Journal of Rheumatology, 2014 May;41(5):938-44.

Nelson AE, Elstad E, DeVellis RF, Schwartz TA, Golightly YM, Renner JB, Conaghan PG, Kraus VB, Jordan JM.  Composite measures of multi-joint symptoms, but not of radiographic osteoarthritis, are associated with functional outcomes: The Johnston County Osteoarthritis Project.  Disability and Rehabilitation 2014;36(4):300-6.


Joanne M. Jordan, MD, MPH Publications:
Genome-wide association study of selenium concentrations.
Cornelis MC, Fornage M, Foy M, Xun P, Gladyshev VN, Morris S, Chasman DI, Hu FB, Rimm EB, Kraft P, Jordan JM, Mozaffarian D, He K.
Hum Mol Genet. 2014 Oct 24. pii: ddu546. [Epub ahead of print]

Lower limb osteoarthritis and the risk of falls in a community-based longitudinal study of adults with and without osteoarthritis.
Doré AL, Golightly YM, Mercer VS, Shi XA, Renner JB, Jordan JM, Nelson AE.
Arthritis Care Res (Hoboken). 2014 Oct 20. doi: 10.1002/acr.22499. [Epub ahead of print]

Meta-analysis of assay sensitivity and study features in clinical trials of pharmacologic treatments for osteoarthritis pain.
Dworkin RH, Turk DC, Peirce-Sandner S, He H, McDermott MP, Hochberg MC, Jordan JM, Katz NP, Lin AH, Neogi T, Rappaport BA, Simon LS, Strand V.
Arthritis Rheumatol. 2014 Sep 3. doi: 10.1002/art.38869. [Epub ahead of print]

Foot disorders associated with overpronated and oversupinated foot function: the johnston county osteoarthritis project.
Golightly YM, Hannan MT, Dufour AB, Hillstrom HJ, Jordan JM.
Foot Ankle Int. 2014 Nov;35(11):1159-65. doi: 10.1177/1071100714543907. Epub 2014 Jul 18.

Genome-wide association and functional studies identify a role for IGFBP3 in hip osteoarthritis.
Evans DS, Cailotto F, Parimi N, Valdes AM, Castaño-Betancourt MC, Liu Y, Kaplan RC, Bidlingmaier M, Vasan RS, Teumer A, Tranah GJ, Nevitt MC, Cummings SR, Orwoll ES, Barrett-Connor E, Renner JB, Jordan JM, Doherty M, Doherty SA, Uitterlinden AG, van Meurs JB, Spector TD, Lories RJ, Lane NE.
Ann Rheum Dis. 2014 Jun 13. pii: annrheumdis-2013-205020. doi: 10.1136/annrheumdis-2013-205020. [Epub ahead of print]

Associations between pressure-pain threshold, symptoms, and radiographic knee and hip osteoarthritis.
Goode AP, Shi XA, Gracely RH, Renner JB, Jordan JM.
Arthritis Care Res (Hoboken). 2014 Oct;66(10):1513-9. doi: 10.1002/acr.22321.

Associations between biomarkers of joint metabolism, hand osteoarthritis, and hand pain and function: the Johnston County Osteoarthritis Project.
Aslam I, Perjar I, Shi XA, Renner JB, Kraus VB, Golightly YM, Jordan JM, Nelson AE.
J Rheumatol. 2014 May;41(5):938-44. doi: 10.3899/jrheum.130904. Epub 2014 Mar 1.

Pharmacologic regimens for knee osteoarthritis prevention: can they be cost-effective?
Losina E, Burbine SA, Suter LG, Hunter DJ, Solomon DH, Daigle ME, Dervan EE, Jordan JM, Katz JN.
Osteoarthritis Cartilage. 2014 Mar;22(3):415-30. doi: 10.1016/j.joca.2014.01.005. Epub 2014 Jan 31.

Race and sex differences in willingness to undergo total joint replacement: the Johnston County Osteoarthritis Project.
Allen KD, Golightly YM, Callahan LF, Helmick CG, Ibrahim SA, Kwoh CK, Renner JB, Jordan JM.
Arthritis Care Res (Hoboken). 2014 Aug;66(8):1193-202. doi: 10.1002/acr.22295.

"Generalized osteoarthritis": a systematic review.
Nelson AE, Smith MW, Golightly YM, Jordan JM.
Semin Arthritis Rheum. 2014 Jun;43(6):713-20. doi: 10.1016/j.semarthrit.2013.12.007. Epub 2013 Dec 31.

A systematic review of recommendations and guidelines for the management of osteoarthritis: The Chronic Osteoarthritis Management Initiative of the U.S. Bone and Joint Initiative.
Nelson AE, Allen KD, Golightly YM, Goode AP, Jordan JM.
Semin Arthritis Rheum. 2014 Jun;43(6):701-12. doi: 10.1016/j.semarthrit.2013.11.012. Epub 2013 Dec 4.

Association analysis of BMD-associated SNPs with knee osteoarthritis.
Yerges-Armstrong LM, Yau MS, Liu Y, Krishnan S, Renner JB, Eaton CB, Kwoh CK, Nevitt MC, Duggan DJ, Mitchell BD, Jordan JM, Hochberg MC, Jackson RD.
J Bone Miner Res. 2014 Jun;29(6):1373-9. doi: 10.1002/jbmr.2160.

Psychometric properties of the foot and ankle outcome score in a community-based study of adults with and without osteoarthritis.
Golightly YM, Devellis RF, Nelson AE, Hannan MT, Lohmander LS, Renner JB, Jordan JM.
Arthritis Care Res (Hoboken). 2014 Mar;66(3):395-403. doi: 10.1002/acr.22162.

Meeting physical activity guidelines and the risk of incident knee osteoarthritis: a population-based prospective cohort study.
Barbour KE, Hootman JM, Helmick CG, Murphy LB, Theis KA, Schwartz TA, Kalsbeek WD, Renner JB, Jordan JM.
Arthritis Care Res (Hoboken). 2014 Jan;66(1):139-46. doi: 10.1002/acr.22120.

Association of incident symptomatic hip osteoarthritis with differences in hip shape by active shape modeling: the Johnston County Osteoarthritis Project.
Nelson AE, Liu F, Lynch JA, Renner JB, Schwartz TA, Lane NE, Jordan JM.
Arthritis Care Res (Hoboken). 2014 Jan;66(1):74-81. doi: 10.1002/acr.22094.

A kinetic and kinematic analysis of the effect of stochastic resonance electrical stimulation and knee sleeve during gait in osteoarthritis of the knee.
Collins A, Blackburn T, Olcott C, Jordan JM, Yu B, Weinhold P.
J Appl Biomech. 2014 Feb;30(1):104-12. doi: 10.1123/jab.2012-0257. Epub 2013 Jul 22.

Composite measures of multi-joint symptoms, but not of radiographic osteoarthritis, are associated with functional outcomes: the Johnston County Osteoarthritis Project.
Nelson AE, Elstad E, DeVellis RF, Schwartz TA, Golightly YM, Renner JB, Conaghan PG, Kraus VB, Jordan JM.
Disabil Rehabil. 2014;36(4):300-6. doi: 10.3109/09638288.2013.790490. Epub 2013 May 3.

Peng Liu, MD, PhD Publications:
Crook KR and Liu P. Role of myeloid-derived suppressor cells in autoimmune disease. World Journal of Immunol 2014; 4(1): 20-25

Crook K, Week MF, Rampersad RR, Baldi MR, and Liu P. Myeloid-derived suppressor cells ameliorate the pathogenesis of autoimmune arthritis. J Immunol 2013; 190:185.3

 

Amanda Nelson, MD, MSCR Publications:
Associations between biomarkers of joint metabolism, hand osteoarthritis, and hand pain and function: the Johnston County Osteoarthritis Project.

(J Rheumatol. 2014 May;41(5):938-44. doi: 10.3899/jrheum.130904. Epub 2014 Mar 1. PubMed PMID: 24584914; PubMed Central PMCID: PMC4008682.
Aslam I, Perjar I, Shi XA, Renner JB, Kraus VB, Golightly YM, Jordan JM, Nelson AE.)

**Imran Aslam and Irina Perjar were medical students who worked with Joanne and I in the summer of 2011**


"Generalized osteoarthritis": A systematic review.
(Semin Arthritis Rheum. 2013 Dec 31. pii: S0049-0172(13)00293-X. doi: 10.1016/j.semarthrit.2013.12.007. [Epub ahead of print] PubMed PMID: 24461078. Nelson AE, Smith MW, Golightly YM, Jordan JM.)

A systematic review of recommendations and guidelines for the management of osteoarthritis: The Chronic Osteoarthritis Management Initiative of the U.S. Bone and Joint Initiative.
(Semin Arthritis Rheum. 2013 Dec 4. pii: S0049-0172(13)00258-8. doi:10.1016/j.semarthrit.2013.11.012. [Epub ahead of print] PubMed PMID: 24387819. Nelson AE, Allen KD, Golightly YM, Goode AP, Jordan JM.) **Mike Smith is a former fellow**

Association of incident symptomatic hip osteoarthritis with differences in hip shape by active shape modeling: the Johnston County Osteoarthritis Project.
(Arthritis Care Res (Hoboken). 2014 Jan;66(1):74-81. doi: 10.1002/acr.22094.PubMed PMID: 23926053; PubMed Central PMCID: PMC3959908. Nelson AE, Liu F, Lynch JA, Renner JB, Schwartz TA, Lane NE, Jordan JM.)


Dr. Dore selected to present his research at the 2014 American College of Rheumatology Research Workshop
Dr. Dore was selected to present his research study “The Relationship between Lower Limb Osteoarthritis Burden and Risk for Falls: The Johnston County Osteoarthritis Project” at the 2014 American College of Rheumatology Research Workshop in Seattle, Washington in June. This course is a two- day workshop designed to promote interactions between young and established investigators to foster collaboration and career mentoring.

 

Bridget Foley, our 2013 summer MSTAR student, presented at the American Geriatric Society meeting.

New Faces

Faculty


Kelli Allen, PhD

Richard Loeser, MD

Jennifer Rogers, MD

 

Staff & Students

During his 15 years as a data analyst John Cantrell (MA) has performed data extraction, transformation, and analysis. He is particularly interest in the use of tables and graphics to effectively present analysis results and in the appropriate application of statistical methods. He is currently a master’s student in the UNC department of Biostatistics. Mr. Cantrell is familiar with a number of different technological tools, including Sybase, Oracle, MS Access/Visual Basic, ArcGIS, STATA, and SAS. SAS is his strongest skill, including data step programming, by group processing, SAS MACRO language, SAS/STAT, SAS Access and pass-through SQL. He has worked with clinical trials data, clinical exam data, geographic data, census data, Medicaid and Medicare claims data, public health surveillance data, motion analysis data, and survey data, supporting clinical trials, preventive care though population health management, and public health. His work in public health includes dental public health, injury prevention, and research on arthritis.
Rebekah “Beka” Layton earned her Ph.D. (Social and Personality Psychology, 2014) and M.A. (Psychology, 2011) from the University at Albany, State University of New York, and her B.A. (Psychology and History & Sociology of Science, 2005) from the University of Pennsylvania. Rebekah is also a veteran of Operation Iraqi Freedom where she served as a Military Police Officer in Baghdad, Iraq. As a paratrooper, she was stationed at Fort Bragg, North Carolina, and completed her active duty service in Seoul, Korea as a Captain in the US Army. Perhaps not surprisingly, her research focus is in self-control and goal-setting, with additional research interests in physical fitness activity, emotion, and mindfulness. Rebekah is thrilled to join the PALS team, led by Christine Rini, here at UNC Chapel Hill. She is joined by her husband Seth, daughter Ariya, cat Sonic, and dog Lola. Rebekah loves to row (crew) and sing in her free time, and is (not so secretly) obsessed with all things Broadway. She originally hails from Rensselaerville, NY, where she grew up in the foothills of the Catskill Mountains, and accordingly also loves hiking (along with pretty much anything to do with the outdoors).
Marjorie Margolis is a graduate research assistant on the Partners in Active Living (PALs) study and is a first year MSPH-PHD student in Health Behavior in the Gillins School of Public Health. She previously worked in health communication research at a nonprofit research institute in RTP. In her free time, she enjoys running, cooking, and baking.
Daniel Newell was raised in Chapel Hill, and graduated from Chapel Hill high school. He went on to get a B.S in psychology at Appalachian State University. After graduation he wanted to see more of the world, and decided to teach English at a South Korean public school. After spending over a year in Korea and traveling around South East Asia, he returned to Chapel Hill and worked as a research assistant for the Carolina Affective Science Laboratory, and The Positive Emotions and Psychophysiology Lab at UNC. His experiences working on behavioral interventions at the P.E.P lab piqued my interest in public health issues and health behavior. He is looking forward to working with and learning from the outstanding range of faculty and staff on the PALS project!
Quinn Williams earned a master’s degree in Social Work at UNC-Chapel Hill. Quinn is a project manager at UNC who has managed complex randomized clinical trials, she has a special interest in behavioral health studies. Quinn currently works with Dr. Kelli Allen on the PATH-IN study, a clinical trial comparing an internet based exercise program to physical therapy for patients with knee osteoarthritis.

 

Loeser Lab

John Collins, PhD received his BSc (Hons) in Sport and Exercise Science from Nottingham Trent University in 2007 and his MMEDSCI in Human Nutrition from the University of Sheffield in 2009. He received his PhD in Musculoskeletal Biology from the University of Liverpool in 2013. Key research interests include chondrocyte redox signaling in osteoarthritis and mitochondrial function in health and disease. He has recently started as a postdoctoral fellow for Dr. Loeser and is looking forward to working alongside everyone at TARC.
Meredith Greene is a fourth year graduate student in the Molecular Medicine and Translational Science program at Wake Forest University and has been working in Dr. Richard Loeser’s lab since January of 2011. She graduated from Campbell University in 2010 with a BS in Biochemistry.
Kathryn Kelley
Scott Wood, PhD received his B.S. in Mechanical Engineering from Texas Tech University in 2005 and his Ph.D. in Bioengineering from Clemson University in 2011. His areas of interest include integrin signaling, redox signaling, and mechanotransduction mechanisms of chondrocytes in OA. He has been working as a postdoctoral fellow for Dr. Loeser for almost two years and is excited to be part of the TARC team.
Mary (Yiwen) Zhao is a Research Technician in the Loeser lab.

 

Liu Lab

Kathryn Pietrosimone is a postdoctoral research associate in the lab of Peng Liu. She graduated with a B.A. in biotechnology and molecular genetics from Assumption College in Worcester, MA. She then moved on to the University of Connecticut where she received her PhD in molecular and cell biology. During her graduate work Kathryn focused on the study of immune cell movement in response to bacterial infections. She is currently studying the recruitment and involvement of immune cell subsets in animal model of rheumatoid arthritis.
Brad Poston, BS, is a research technician in Dr. Liu's lab and a recent graduate of NC State University. He is interested in studying autoimmunity and is an aspiring physician that hopes to specialize in Rheumatology & Immunology.

 

Su Lab

Pearl Vijay Bakhru

 

Former staff

Amy Glekas, PhD, is a postdoctoral fellow who recently received her PhD in Biochemistry from the University of Illinois, Urbana-Champaign where she worked on the effects of abiotic stresses on plant genetics. She is enjoying the challenge of changing research fields and is thrilled to be working on rheumatoid arthritis in Dr. Liu’s laboratory. "Living in North Carolina has been a joy, and I have already decided that I never want to leave!"
Jamie Stiller worked with Drs. Amanda Nelson and Yvonne Golightly as a Research Associate funded in part by our UNC Junior Faculty Development Award. She provided research support for osteoarthritis grants focused on hip shape morphology and leg length inequality. Jamie earned her Master of Public Health degree with a concentration in Health Behavior in 2010 from the University of Alabama at Birmingham and was recently accepted to UNC’s Master of Science in Occupational Therapy program. She started her master's program this fall and we wish her much success.
Amanda Wohlfarth joined us as a temporary part-time accounting technician. She holds a full-time position as an accounting technician for NC Botanical Garden and graduated in 2012 from UNC-Wilmington with majors in Film and English. After graduation, Amanda has held positions in web development and film editing before moving to Chapel Hill. We appreciated Amanda's temporary assistance and wish her the best.

Please join us in welcoming all of our new faces to the Division and Center!


~ The faculty and staff of the Thurston Arthritis Research Center