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ADME Mass Spectrometry Center

Director: Arlene S. Bridges, Ph.D.
mslogo

 

Contact Information:

Phone: (919) 428-3479
Fax: (919) 966-0704

Location:  517-520 Brinkhous-Bullitt Bldg. and 3323 Kerr Hall
Email: argolye@isis.unc.edu

 

 

Equipment Available

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  Fees

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Recent Publications

 

The goals of the ADME Mass Spectrometry Center include:


  • molecular weight determination by ion trap mass spectrometry
  • structural analysis by ion trap mass spectrometry
  • quantitation by triple quadrupole mass spectrometry

 

 

 

Equipment Available:

 

 Triple quadrupole mass spectrometers

  • Applied Biosystems ABI4000

Leap thermostatted autosampler

Shimadzu solvent delivery system

Positive/negative mode

Turboionspray/APCI

api4000

  • Applied Biosystems ABI3000

    masspec

Leap autosampler

Shimadzu solvent delivery system

Positive/negative mode

Turboionspray/APCI

  • Thermo-Scientific Quantum Ultra

Leap thermostatted autosampler

Shimadzu solvent delivery system

Positive/negative mode

Electrospray/APCI

 masspec

Ion trap mass spectrometer

  • Agilent MSD-trap

Agilent 1100-DAD-FLD

Direct infusion

Positive/negative mode

Electrospray

iontrap

Preparative HPLC system

  • Varian 320

Up to 100 mL injection volume

UV detector

Fraction collector

Analytical HPLC systems

  • Agilent 1100 HPLC-DAD-FLD (3)

  • HP1050 HPLC-UV

 hplc

Sample handling

  • Apricot Designs 96-well evaporator

  • Plate vortexer

  • Multi-channel pipettors

Repeat pipettors

 evap

 

Fees:

Fees are calculated based on instrument run-time and are dependent upon funding source. Please contact the Director directly for more information.

Recent Publications:

Click here for a list of recent publications by the ADME Center on PubMed
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