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Graduate Students
Rachel Beaulieu Goldsmith |  | Project Name: A Comparison of the Differences in Disposition and Mechanism of Transport of Furamidine (DB75) and DB829 in the Kidney
Description: The goal of this project is to characterize the difference in kidney disposition of furamidine and DB829 in rats. This will be accomplished quantitatively by LC/MS/MS and qualitatively with immunohistochemistry. Additionally, the prodrugs of these compounds, pafuramidine and DB868, will be studied to confirm the dissimilarity in distribution of the active compound in kidney. Subsequently, the mechanisms that cause this difference in disposition will be investigated with the expectation that the results may reveal potential causes for the delayed term nephrotoxicity of pafuramidine observed in human subjects. | | Email: regold@email.unc.edu | Expected Graduation Date: May 2011 | | Click here to see Rachel's publications on PubMed. |
Pathology Graduate Student, Rachel B. Goldsmith, Receives ASTMH Award | | Rachel Goldsmith, a graduate student in the Pathology Department of the UNC School of Medicine, received a runner-up Young Investigator Award and $250 for her poster presentation at the Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH). The 58th ASTMH meeting held in Washington, DC in November of 2009 was attended by more than 3,000 scientists, clinicians, and students. Goldsmith's poster "Organ Specific Accumulation and Distribution of Structurally Related Anti-Trypanosomal Compounds: A Possible Role in Renal Toxicity" was selected to be defended orally before a panel of ASTMH judges and was chosen from a field of close competitors from internationally renowned institutions. |   | | Front row: third from left, Rachel Goldsmith |
Due to the restrictions on his current funding,
Dr. Tidwell is not accepting any new graduate students. |  |
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