Curriculum Member Profiles

Trevor Archer

Molecular carcinogenesis: cancer, chromatin, transcription, and epigenetics

Trevor Archer - Read More…

Antonio Baines

Validate novel molecular targets (ex. oncogenic PIM kinases) for potential therapeutic intervention in pancreatic cancer and other cancers as well as test novel PIM kinase inhibitors in combination with chemotherapy.

Antonio Baines - Read More…

Linda Birnbaum

Pharmacokinetic behavior of environmental chemicals, mechanisms of action of toxicants including endocrine disruptors, and linking of real-world exposures to health effects

Linda Birnbaum - Read More…

Thomas Bouldin

Cellular response to toxic injury in the central and peripheral nervous systems; neuropathology; ocular pathology; and pathology of peripheral neuropathies

Thomas Bouldin - Read More…

Kim Brouwer

Hepatobiliary xenobiotic disposition, hepatotoxicity and pharmacokinetics

Kim Brouwer - Read More…

Frank Church

Breast and prostate carcinogenesis, macromolecular structure-function, molecular pathology

Frank Church - Read More…

William Coleman

Molecular pathogenesis of liver and breast cancer, and liver progenitor cell biology

William Coleman - Read More…

Marila Cordeiro-Stone

DNA replication, DNA repair, and cell cycle checkpoints in human cells; mechanisms of carcinogenesis by solar radiation; pathogenesis of melanoma

Marila Cordeiro-Stone - Read More…

Daniel Costa

Mechanisms of air pollutant-induced adverse cardiopulmonay and neurophysiological health effects

Daniel Costa - Read More…

Kevin Crofton

Understanding the consequences of endocrine disruption on neurodevelopment

Kevin Crofton - Read More…

Channing Der

The role of the ras oncogne, ras-mediated signalling and ras-related small GTPases in cancer and development of anti-ras inhibitors

Channing Der - Read More…

Mohanish Deshmukh

Regulation of programmed cell death in postmitotic, senescent, neoplastic and stem cells.

Mohanish Deshmukh - Read More…

Michael DeVito

Pharmacokinetics and mechanisms of chemical-mediated toxicity and carcinogenicity

Michael DeVito - Read More…

Robert Devlin

Pulmonary toxicology and molecular biology

Robert Devlin - Read More…

David Diaz-Sanchez

Environmental impacts on human health, genetic susceptibility, immunology, epigenetics, translational research

David Diaz-Sanchez - Read More…

Kevin Dreher

Development of alternative testing methods predictive of in vivo cardiovascular toxicity of chemicals and engineered nanomaterials.

Kevin Dreher - Read More…

Aimen Farraj

Mechanisms of health effects of environmental pollution on cardiopulmonary function, animal models of cardiovascular diseases, targeted and high throughput technology

Aimen Farraj - Read More…

Suzanne Fenton

Epidermal growth factor receptor and its ligands and signaling mechanisms of endocrine disrupting toxicants in the mammary gland

Suzanne Fenton - Read More…

Michael Fessler

Mechanisms of induction and regulation of the innate immune response, with a focus on Toll like Receptors (TLRs).

Michael Fessler - Read More…

Rebecca Fry

Toxicogenomic and systems biology approaches to understanding the mechanisms of metal-induced disease and the basis for inter-individual disease susceptibility

Rebecca Fry - Read More…

Ian Gilmour

The interaction between air pollutant exposure and the development of infectious and allergic lung disease

Ian Gilmour - Read More…

Avram Gold

Chemistry of protein and DNA adducts

Avram Gold - Read More…

Jean Harry

Role of microglia in immune-mediated responses in brain development, repair, aging and disease

Jean Harry - Read More…

Neil Hayes

Lung carcinogenesis, research translation, biomarkers, computational toxicology

Neil Hayes - Read More…

Mehdi Hazari

Neurophysiological mechanisms mediating cardiopulmonary dysfunction due to air pollution exposure.

Mehdi Hazari - Read More…

Michelle Hernandez

Testing therapeutic interventions against pollutant-induced inflammation.

Michelle Hernandez - Read More…

Sidney Hunter

Mechanisms of toxocant-induced craniofacial birth defects

Sidney Hunter - Read More…

Ilona Jaspers

Mechanisms by which air pollutants enhance susceptibility to and the severity of respiratory virus infections

Ilona Jaspers - Read More…

William Kaufmann

Computational modeling of DNA repair and checkpoint pathways; systems of protection of genetic stability

William Kaufmann - Read More…

Samir Kelada

Gene-environment Interactions in Airway Diseases

Samir Kelada - Read More…

Steven Kleeberger

Genetic determinants of environmental lung diseases

Steven Kleeberger - Read More…

Urmila Kodavanti

Cardiovascular disease and susceptibility, air pollutants, cardiopulmonary interactions, molecular mechanisms, genetic and environmental factors

Urmila Kodavanti - Read More…

Ed LeCluyse

The use of in vitro cell-based hepatic culture models to investigate mechanisms of compound-induced hepatotoxicity.

Ed LeCluyse - Read More…

Robert Luebke

Understanding the underlying mechanisms responsible for modulation of normal immune function by environmental agents and the development of alternative testing methods for screening/testing immunotoxicants.

Robert Luebke - Read More…

Jeffrey Macdonald

Metabolomics, tissue engineering and systems biology

Jeffrey Macdonald - Read More…

Michael Madden

Mechanisms of ambient air pollutant-induced cardiopulmonary morbidity and mortality

Michael Madden - Read More…

Nobuyo Maeda

Genetics and molecular pathology of obesity, diabetes, hypercholesterolemia, insulin resistance, and hypertension

Nobuyo Maeda - Read More…

Shaun McCullough

Environmental and public health epigenetics, translational research, molecular and mechanistic toxicology, advanced in vitro models

Shaun McCullough - Read More…

Leslie Morrow

Neurotoxicology and excitotoxicity of alcohol

Leslie Morrow - Read More…

Michael Narotsky

Endocrinology of pregnancy and parturition and reproductive and developmental toxicity

Michael Narotsky - Read More…

Leena Nylander-French

Pharmacogenetics of detoxification pathways in skin and inhalation exposures to toxicants; mathematical and statistical exposure modeling for risk assessment

Leena Nylander-French - Read More…

David Peden

Translational and clinical research in environmental lung disease

David Peden - Read More…

Charles Perou

Use of animal models to mimic findings of biological diversity in human cancers; develop predictive computational models to test new therapeutics specific for tumor subtypes

Charles Perou - Read More…

Daniel Pomp

Polygenic basis of complex traits and gene-environment interactions

Daniel Pomp - Read More…

Ram Ramabhadran

Neurotoxicological effects of environmental pollutants, cellular stress pathways

Ram Ramabhadran - Read More…

Dale Ramsden

Mechanisms of chromosome strand break repair

Dale Ramsden - Read More…

Scott Randell

Airway epithelial cell biology, pulmonary innate immunity and transplant pathophysiology

Scott Randell - Read More…

James Samet

Cell and molecular mechanisms of inflammatory responses induced by inhalation of ambient air pollutants

James Samet - Read More…

Aziz Sancar

Biochemical mechanisms of nucleotide excision repair, DNA damage cell cycle checkpoints, and circadian rhythm

Aziz Sancar - Read More…

Norman Sharpless

Mechanisms of stem cell senescence; genetics of the INK4/ARF tumor suppressor locus in melanoma; melanoma therapeutics

Norman Sharpless - Read More…

Miroslav Styblo

Metabolic interactions of essential microelements, especially trace metals, with toxic metals and metalloids that contaminate food and drinking water

Miroslav Styblo - Read More…

James Swenberg

Mechanisms of DNA damage and repair; molecular epidemiology; development of ultra-sensitive and specific methods for measuring chemical adducts in DNA and hemoglobin

James Swenberg - Read More…

Nancy Thomas

Molecular carcinogenesis, environmental toxicology, molecular epidemiology of melanomas, research translation, biomarkers

Nancy Thomas - Read More…

Alexander Tropsha

Biomolecular informatics; molecular structure-function modeling using statistical and machine learning approaches

Alexander Tropsha - Read More…

Cyrus Vaziri

Control mechanisms of DNA replication during normal passage through an unperturbed cell cycle and in response to DNA-damaging agents

Cyrus Vaziri - Read More…

Paul Watkins

Mechanistic toxicology, hepatic toxicology, research translation, biomarkers

Paul Watkins - Read More…

Bernard Weissman

Chromatin remodeling and epigenetic alterations in human cancers

Bernard Weissman - Read More…

Carmen Williams

Basic reproductive biology of early mammalian embryogenesis, epigenetics, and how the environment impacts reproduction.

Carmen Williams - Read More…

Elizabeth Wilson

Mechanisms of androgen receptor (AR) regulation of gene transcription and cell proliferation in the human male and female reproductive tracts

Elizabeth Wilson - Read More…