Curriculum Member Profiles

Trevor Archer
Molecular carcinogenesis: cancer, chromatin, transcription, and epigenetics
Louise Ball
Toxicology of food additives, contaminants and environmental pollutants
Linda Birnbaum
Pharmacokinetic behavior of environmental chemicals, mechanisms of action of toxicants including endocrine disruptors, and linking of real-world exposures to health effects
Thomas Bouldin
Cellular response to toxic injury in the central and peripheral nervous systems; neuropathology; ocular pathology; and pathology of peripheral neuropathies
Kim Brouwer
Hepatobiliary xenobiotic disposition, hepatotoxicity and pharmacokinetics
Ronald Cannon
Early events in skin tumor development
Martha Sue Carraway
In vitro and translational approaches to studying the mechanisms of endothelial and vascular injury in response to inhaled air pollutants, including activation of coagulation and reactive oxygen species generation.
Frank Church
Breast and prostate carcinogenesis, macromolecular structure-function, molecular pathology
Kevin Crofton
Understanding the consequences of endocrine disruption on neurodevelopment
William Coleman
Molecular pathogenesis of liver and breast cancer, and liver progenitor cell biology
Marila Cordeiro-Stone
DNA replication, DNA repair, and cell cycle checkpoints in human cells; mechanisms of carcinogenesis by solar radiation; pathogenesis of melanoma
Daniel Costa
Mechanisms of air pollutant-induced adverse cardiopulmonay and neurophysiological health effects
Channing Der
The role of the ras oncogne, ras-mediated signalling and ras-related small GTPases in cancer and development of anti-ras inhibitors
Mohanish Deshmukh
Regulation of programmed cell death in postmitotic, senescent, neoplastic and stem cells.
Michael DeVito
Pharmacokinetics and mechanisms of chemical-mediated toxicity and carcinogenicity
Robert Devlin
Pulmonary toxicology and molecular biology
David Diaz-Sanchez
Environmental impacts on human health, genetic susceptibility, immunology, epigenetics, translational research
Kevin Dreher
Development of alternative testing methods predictive of in vivo cardiovascular toxicity of chemicals and engineered nanomaterials.
Aimen Farraj
Mechanisms of health effects of environmental pollution on cardiopulmonary function, animal models of cardiovascular diseases, targeted and high throughput technology
Suzanne Fenton
Epidermal growth factor receptor and its ligands and signaling mechanisms of endocrine disrupting toxicants in the mammary gland
Michael Fessler
Mechanisms of induction and regulation of the innate immune response, with a focus on Toll like Receptors (TLRs).
Rebecca Fry
Toxicogenomic and systems biology approaches to understanding the mechanisms of metal-induced disease and the basis for inter-individual disease susceptibility
Ian Gilmour
The interaction between air pollutant exposure and the development of infectious and allergic lung disease
Avram Gold
Chemistry of protein and DNA adducts
Jean Harry
Role of microglia in immune-mediated responses in brain development, repair, aging and disease
Neil Hayes
Lung carcinogenesis, research translation, biomarkers, computational toxicology
Mehdi Hazari
Neurophysiological mechanisms mediating cardiopulmonary dysfunction due to air pollution exposure.
Michelle Hernandez
Testing therapeutic interventions against pollutant-induced inflammation.
Sidney Hunter
Mechanisms of toxocant-induced craniofacial birth defects
Ilona Jaspers
Mechanisms by which air pollutants enhance susceptibility to and the severity of respiratory virus infections
William Kaufmann
Computational modeling of DNA repair and checkpoint pathways; systems of protection of genetic stability
Steven Kleeberger
Genetic determinants of environmental lung diseases
Urmila Kodavanti
Cardiovascular disease and susceptibility, air pollutants, cardiopulmonary interactions, molecular mechanisms, genetic and environmental factors
Ed LeCluyse
The use of in vitro cell-based hepatic culture models to investigate mechanisms of compound-induced hepatotoxicity.
Robert Luebke
Understanding the underlying mechanisms responsible for modulation of normal immune function by environmental agents and the development of alternative testing methods for screening/testing immunotoxicants.
Jeffrey Macdonald
Metabolomics, tissue engineering and systems biology
Michael Madden
Mechanisms of ambient air pollutant-induced cardiopulmonary morbidity and mortality
Nobuyo Maeda
Genetics and molecular pathology of obesity, diabetes, hypercholesterolemia, insulin resistance, and hypertension
Terry Magnuson
Mammalian Genetics/Genomics/Development/Mouse Models of Human Disease
Leslie Morrow
Neurotoxicology and excitotoxicity of alcohol
Michael Narotsky
Endocrinology of pregnancy and parturition and reproductive and developmental toxicity
Leena Nylander-French
Pharmacogenetics of detoxification pathways in skin and inhalation exposures to toxicants; mathematical and statistical exposure modeling for risk assessment
Mary Paine
Drug xenobiotic metabolism, pharmacokinetics, drug xenobiotic interactions
Campbell Patterson
Vascular biology, angiogenesis, and protein folding and degradation
David Peden
Translational and clinical research in environmental lung disease
Charles Perou
Use of animal models to mimic findings of biological diversity in human cancers; develop predictive computational models to test new therapeutics specific for tumor subtypes
Daniel Pomp
Polygenic basis of complex traits and gene-environment interactions
Scott Randell
Airway epithelial cell biology, pulmonary innate immunity and transplant pathophysiology
Ram Ramabhadran
Neurotoxicological effects of environmental pollutants, cellular stress pathways
Dale Ramsden
Mechanisms of chromosome strand break repair
Kimryn Rathmell
Genetics of renal cell carcinoma
Ivan Rusyn
Environmental Genomics
James Samet
Cell and molecular mechanisms of inflammatory responses induced by inhalation of ambient air pollutants
Aziz Sancar
Biochemical mechanisms of nucleotide excision repair, DNA damage cell cycle checkpoints, and circadian rhythm
Norman Sharpless
Mechanisms of stem cell senescence; genetics of the INK4/ARF tumor suppressor locus in melanoma; melanoma therapeutics
Miroslav Styblo
Metabolic interactions of essential microelements, especially trace metals, with toxic metals and metalloids that contaminate food and drinking water
Kathleen Sulik
Birth defects, neuroteratology, fetal alcohol spectrum disorders, high resolution magnetic resonance imaging
James Swenberg
Mechanisms of DNA damage and repair; molecular epidemiology; development of ultra-sensitive and specific methods for measuring chemical adducts in DNA and hemoglobin
Nancy Thomas
Molecular carcinogenesis, environmental toxicology, molecular epidemiology of melanomas, research translation, biomarkers
Alexander Tropsha
Biomolecular informatics; molecular structure-function modeling using statistical and machine learning approaches
Cyrus Vaziri
Control mechanisms of DNA replication during normal passage through an unperturbed cell cycle and in response to DNA-damaging agents
Paul Watkins
Mechanistic toxicology, hepatic toxicology, research translation, biomarkers
Bernard Weissman
Chromatin remodeling and epigenetic alterations in human cancers
Carmen Williams
Basic reproductive biology of early mammalian embryogenesis, epigenetics, and how the environment impacts reproduction.
Elizabeth Wilson
Mechanisms of androgen receptor (AR) regulation of gene transcription and cell proliferation in the human male and female reproductive tracts
Lee Graves
Milan Hazucha
David Holbrook
David Kaufman
Gary Klinefelter
Patricia Maness
Axon Guidance and Signal Transduction in Nervous System Development
Ronald Mason
MaryJane Selgrade
Stephanie Padilla
David W. Threadgill
Kenneth Tindall
Gregory Travlos
Rochelle Tyl
Douglas Wolf