Charles Perou

Use of animal models to mimic findings of biological diversity in human cancers; develop predictive computational models to test new therapeutics specific for tumor subtypes

Institution:  University of North Carolina School of Medicine

Website:  http://cancer.unc.edu/research/faculty/displayMember.asp?ID=244

Email:  cperou@med.unc.edu

Voice:  (919) 843-5740

Publications

Human carcinomas show great diversity in their morphologies, clinical histories and in their responsiveness to therapy. This wide tumor diversity poses the main challenge to the effective treatment of cancer patients. The main focus of the Perou Lab is to characterize the biology diversity of human tumors using microarray analysis, genomics, molecular genetics, and cell biology, and then to mimic these findings in animal models. We ultimately use these animal systems to develop predictive computational models and to test new therapeutics that are specific for each tumor subtype.