Trevor Archer

Molecular carcinogenesis: cancer, chromatin, transcription, and epigenetics

Louise Ball

Toxicology of food additives, contaminants and environmental pollutants

Linda Birnbaum

Pharmacokinetic behavior of environmental chemicals, mechanisms of action of toxicants including endocrine disruptors, and linking of real-world exposures to health effects

Thomas Bouldin

Cellular response to toxic injury in the central and peripheral nervous systems; neuropathology; ocular pathology; and pathology of peripheral neuropathies

Kim Brouwer

Hepatobiliary xenobiotic disposition, hepatotoxicity and pharmacokinetics

Ronald Cannon

Early events in skin tumor development

Martha Sue Carraway

In vitro and translational approaches to studying the mechanisms of endothelial and vascular injury in response to inhaled air pollutants, including activation of coagulation and reactive oxygen species generation.

Frank Church

Breast and prostate carcinogenesis, macromolecular structure-function, molecular pathology

Kevin Crofton

Understanding the consequences of endocrine disruption on neurodevelopment

William Coleman

Molecular pathogenesis of liver and breast cancer, and liver progenitor cell biology

Marila Cordeiro-Stone

DNA replication, DNA repair, and cell cycle checkpoints in human cells; mechanisms of carcinogenesis by solar radiation; pathogenesis of melanoma

Daniel Costa

Mechanisms of air pollutant-induced adverse cardiopulmonay and neurophysiological health effects

Channing Der

The role of the ras oncogne, ras-mediated signalling and ras-related small GTPases in cancer and development of anti-ras inhibitors

Mohanish Deshmukh

Regulation of programmed cell death in postmitotic, senescent, neoplastic and stem cells.

Michael DeVito

Pharmacokinetics and mechanisms of chemical-mediated toxicity and carcinogenicity

Robert Devlin

Pulmonary toxicology and molecular biology

David Diaz-Sanchez

Environmental impacts on human health, genetic susceptibility, immunology, epigenetics, translational research

Kevin Dreher

Development of alternative testing methods predictive of in vivo cardiovascular toxicity of chemicals and engineered nanomaterials.

Aimen Farraj

Mechanisms of health effects of environmental pollution on cardiopulmonary function, animal models of cardiovascular diseases, targeted and high throughput technology

Suzanne Fenton

Epidermal growth factor receptor and its ligands and signaling mechanisms of endocrine disrupting toxicants in the mammary gland

Michael Fessler

Mechanisms of induction and regulation of the innate immune response, with a focus on Toll like Receptors (TLRs).

Rebecca Fry

Toxicogenomic and systems biology approaches to understanding the mechanisms of metal-induced disease and the basis for inter-individual disease susceptibility

Ian Gilmour

The interaction between air pollutant exposure and the development of infectious and allergic lung disease

Avram Gold

Chemistry of protein and DNA adducts

Jean Harry

Role of microglia in immune-mediated responses in brain development, repair, aging and disease

Neil Hayes

Lung carcinogenesis, research translation, biomarkers, computational toxicology

Mehdi Hazari

Neurophysiological mechanisms mediating cardiopulmonary dysfunction due to air pollution exposure.

Michelle Hernandez

Testing therapeutic interventions against pollutant-induced inflammation.

Sidney Hunter

Mechanisms of toxocant-induced craniofacial birth defects

Ilona Jaspers

Mechanisms by which air pollutants enhance susceptibility to and the severity of respiratory virus infections

William Kaufmann

Computational modeling of DNA repair and checkpoint pathways; systems of protection of genetic stability

Steven Kleeberger

Genetic determinants of environmental lung diseases

Urmila Kodavanti

Cardiovascular disease and susceptibility, air pollutants, cardiopulmonary interactions, molecular mechanisms, genetic and environmental factors

Ed LeCluyse

The use of in vitro cell-based hepatic culture models to investigate mechanisms of compound-induced hepatotoxicity.

Robert Luebke

Understanding the underlying mechanisms responsible for modulation of normal immune function by environmental agents and the development of alternative testing methods for screening/testing immunotoxicants.

Jeffrey Macdonald

Metabolomics, tissue engineering and systems biology

Michael Madden

Mechanisms of ambient air pollutant-induced cardiopulmonary morbidity and mortality

Nobuyo Maeda

Genetics and molecular pathology of obesity, diabetes, hypercholesterolemia, insulin resistance, and hypertension

Terry Magnuson

Mammalian Genetics/Genomics/Development/Mouse Models of Human Disease

Leslie Morrow

Neurotoxicology and excitotoxicity of alcohol

Michael Narotsky

Endocrinology of pregnancy and parturition and reproductive and developmental toxicity

Leena Nylander-French

Pharmacogenetics of detoxification pathways in skin and inhalation exposures to toxicants; mathematical and statistical exposure modeling for risk assessment

Mary Paine

Drug xenobiotic metabolism, pharmacokinetics, drug xenobiotic interactions

Campbell Patterson

Vascular biology, angiogenesis, and protein folding and degradation

David Peden

Translational and clinical research in environmental lung disease

Charles Perou

Use of animal models to mimic findings of biological diversity in human cancers; develop predictive computational models to test new therapeutics specific for tumor subtypes

Daniel Pomp

Polygenic basis of complex traits and gene-environment interactions

Scott Randell

Airway epithelial cell biology, pulmonary innate immunity and transplant pathophysiology

Ram Ramabhadran

Neurotoxicological effects of environmental pollutants, cellular stress pathways

Dale Ramsden

Mechanisms of chromosome strand break repair

Kimryn Rathmell

Genetics of renal cell carcinoma

Ivan Rusyn

Environmental Genomics

James Samet

Cell and molecular mechanisms of inflammatory responses induced by inhalation of ambient air pollutants

Aziz Sancar

Biochemical mechanisms of nucleotide excision repair, DNA damage cell cycle checkpoints, and circadian rhythm

Norman Sharpless

Mechanisms of stem cell senescence; genetics of the INK4/ARF tumor suppressor locus in melanoma; melanoma therapeutics

Miroslav Styblo

Metabolic interactions of essential microelements, especially trace metals, with toxic metals and metalloids that contaminate food and drinking water

Kathleen Sulik

Birth defects, neuroteratology, fetal alcohol spectrum disorders, high resolution magnetic resonance imaging

James Swenberg

Mechanisms of DNA damage and repair; molecular epidemiology; development of ultra-sensitive and specific methods for measuring chemical adducts in DNA and hemoglobin

Nancy Thomas

Molecular carcinogenesis, environmental toxicology, molecular epidemiology of melanomas, research translation, biomarkers

Alexander Tropsha

Biomolecular informatics; molecular structure-function modeling using statistical and machine learning approaches

Cyrus Vaziri

Control mechanisms of DNA replication during normal passage through an unperturbed cell cycle and in response to DNA-damaging agents

Paul Watkins

Mechanistic toxicology, hepatic toxicology, research translation, biomarkers

Bernard Weissman

Chromatin remodeling and epigenetic alterations in human cancers

Carmen Williams

Basic reproductive biology of early mammalian embryogenesis, epigenetics, and how the environment impacts reproduction.

Elizabeth Wilson

Mechanisms of androgen receptor (AR) regulation of gene transcription and cell proliferation in the human male and female reproductive tracts

Lee Graves

Milan Hazucha

David Holbrook

David Kaufman

Gary Klinefelter

Patricia Maness

Axon Guidance and Signal Transduction in Nervous System Development

Ronald Mason

MaryJane Selgrade

Stephanie Padilla

David W. Threadgill

Kenneth Tindall

Gregory Travlos

Rochelle Tyl

Douglas Wolf