Research Translation
Basic research into the mechanisms of environmentally-relevant disease has accelerated in recent years, but the knowledge gained has been slow to reach the bedside. Both the translation of basic research knowledge into improved understanding of the disease etiology and the translation of clinical insights into hypotheses that can be validated in the laboratory are critical needs in toxicology, in general, and in training, in particular. There is a unique clinical, hands-on patient perspective that an MD or a DVM brings to environmental health sciences research. Physician-scientists are trained to ask clinically relevant questions that lead to faster development and translation of scientific findings into clinical treatment. Importantly, their research projects are highly collaborative with basic scientists and serve as unique opportunity for training in bench-to-bedside-to-bench translational projects. Fortunately, many physician-scientists in this training program not only play a critical role in identifying clinical questions and implementing advances in the basic sciences, but also have considerable financial resources, desire, and human patient/volunteer populations available for translational studies. The Lineberger Comprehensive Cancer Center (with a $150,000,000 Carolina Cancer Hospital to open in 2009), General Clinical Research Center, and the EPA Human Studies Facility at UNC-CH are three primary settings for translational research and training available to the trainees in this program.
Faculty
- Brouwer, Kim R., PhD
- Carey, Lisa A., MD
- Chaney, Stephen G., PhD
- Coleman, William B., PhD
- Der, Channing J., PhD
- Deshmukh, Monhanish P., PhD
- Devlin, Robert D., PhD
- Gammon, Marilie D., PhD
- Graves, Lee M., PhD
- Hayes, D. Neil, MD
- Jaspers, Ilona, PhD
- Kaufman, David G., MD, PhD
- Kaufmann, William K., PhD
- Kleeberger, Steven R., PhD
- Madden, Michael C., PhD
- Millikan, Robert C., DVM, PhD
- Olshan, Andrew F., PhD
- Patterson, W. Campbell, MD
- Peden, David B., MD
- Perou, Charles M., PhD
- Rathmell, W. Kimryn, MD, PhD
- Roth, Bryan L., MD, PhD
- Samet, James M., PhD
- Smith, Philip C., PhD
- Styblo, Miroslav, PhD
- Swenberg, James A., DVM, PhD
- Thomas, Nancy E., MD, PhD
- Watkins, Paul B., MD
- Wolf, Douglas C., DVM, PhD