|Research Interests: Pesticide mode of action, hepatic xenobiotic metabolism, bioinformatics.|
Differential Regulation of Hepatic Oct1, Oatp1a4, Bsep, and Mrp2 Transporter Expression in Lymphocyte-deficient mice Associates with IL-6 Production. Bodeman CE, Dzierlenga AL, Tally CM, Mulligan RM, Lake AD, Cherrington NJ, McKarns SC. J Pharmacol Exp Ther. 2013 Aug 8.
Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease. Lake AD, Novak P, Shipkova P, Aranibar N, Robertson D, Reily MD, Lu Z, Lehman-McKeeman LD, Cherrington NJ. Toxicol Appl Pharmacol. 2013 Apr 15;268(2):132-40.'
Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease. Hardwick RN, Ferreira DW, More VR, Lake AD, Lu Z, Manautou JE, Slitt AL, Cherrington NJ. Drug Metab Dispos. 2013 Mar; 41(3):554-61.
Altered arsenic disposition in experimental nonalcoholic fatty liver disease. Canet MJ, Hardwick RN, Lake AD, Kopplin MJ, Scheffer GL, Klimecki WT, Gandolfi AJ, Cherrington NJ. Drug Metab Dispos. 2012 Sep; 40(9):1817-24.
Analysis of global and absorption, distribution, metabolism, and elimination gene expression in the progressive stages of human nonalcoholic fatty liver disease. Lake AD, Novak P, Fisher CD, Jackson JP, Hardwick RN, Billheimer DD, Klimecki WT, Cherrington NJ. Drug Metab Dispos. 2011 Oct; 39(10):1954-60.
Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease. Hardwick RN, Fisher CD, Canet MJ, Lake AD, Cherrington NJ. Drug Metab Dispos. 2010 Dec; 38(12):2293-301.
Development of high-yield autofluorescent protein microarrays using hybrid cell-free expression with combined Escherichia coli S30 and wheat germ extracts.
Henderson DC, Phillips KC, Lake AD, Galbraith DW. Proteome Sci. 2010 Jun 15;8:32.'