Jaime Cyphert

Postdoctoral Fellow

Contact Information

  • Email:  cjaime@med.unc.edu
  • Office:  (919) 541-3469
  • Location:  B553-A, US Environmental Protection Agency Main Campus
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Education

  • B.S, Biological Sciences, Clemson University, 2004
  • Ph.D., Genetics and Molecular Biology, University of North Carolina at Chapel Hill, 2009
  • Joined the Curriculum in Toxicology in 2010
  • Adviser:  Stephen Gavett

Research Interests

Jaime Cyphert received her PhD in Genetics and Molecular Biology from University of North Carolina in 2009, where she studied immune-neural interactions in allergic bronchoconstriction. In July 2010 she joined the EPA/UNC Toxicology Research Program and has been involved in research associated with the Libby Action Plan. Her research involves assessing the pulmonary toxicity of Libby amphibole compared to other naturally occurring environmental asbestos samples, specifically studying inflammation and lung injury associated with asbestos exposure and their relationships to fibrosis and carcinogenicity. In addition to the asbestos studies, she also collaborates on a study of toxicological effects of inhalation exposure to bio-diesel fuel, assessing airway mechanics after exposure and whether allergic status modulates the response.

Publications

Cyphert, JM; Padilla-Carlin, DJ; Schladweiler MC; Shannahan JH; Nyska, A; Kodavanti, UP; Gavett, SH. 2012. Long term responses of rats to single intratracheal exposure to Libby amphibole (LA) or amosite. Journal of Toxicology and Environmental Health- Part A [in press].

Cyphert, JM; Allen, IC; Cote, RJ; Latour, AM; Snouwaert, JN; Coffman, TM; Koller, BH. 2012. Allergic inflammation induces a persistent mechanistic switch in thromboxane-mediated airway constriction in the mouse. American Journal of Physiology- Lung Cellular and Molecular Physiology, 302(1): L140-151.

Cyphert, JM; Kovarova, M; Koller, BH. 2011. Unique populations of lung mast cells are required for antigen-mediated bronchoconstriction. Journal of Clinical and Experimental Allergy, 41(2):260-9.

Cyphert, JM. 2009. (Dissertation) Regulation of airway reactivity: Interactions between neuronal and immune pathways in the lung. The University of North Carolina at Chapel Hill, 246 pages, publication #3387978.

Cyphert, JM; Kovarova, M; Allen, IC; Hartney, JM; Murphy, DL; Wess, J; Koller, BH. 2009. Cooperation between mast cells and neurons is essential for antigen-mediated bronchoconstriction. The Journal of Immunology, 182: 7430-7439.

Personal Interests

Horseback riding, pilates, yoga, golfing, disc golf, bad horror movies, sci fi/fantasy books