Research Projects
Other Projects
National Institutes of Health (NIH)
Pharmaceutical Companies
In addition to funding through the National Institutes of Health (NIH) and pharmaceutical companies, the Center has received research grants and contracts from a variety of other sources.
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Other Projects
National Institutes of Health (NIH)
Pharmaceutical CompaniesIn addition to funding through the National Institutes of Health (NIH) and pharmaceutical companies, the Center has received research grants and contracts from a variety of other sources.
Un-numbered (Whitehead, Drossman, Co-PI) -- Rome Foundation
Validation of the Rome III Questionnaire and Evaluation of Response Frequencies
This subcontract has as its aims: (1) assess the understandability of individual questions in the Rome III Modular Questionnaire, (2) assess test-retest reliability of individual questions and diagnoses based on the Rome III diagnostic criteria, (3) describe the frequency of occurrence of individual symptoms in a large group of healthy controls to provide guidance to the Rome committees in setting thresholds for diagnosis, and (4) assess the sensitivity and specificity of the Rome III diagnoses by comparison to medically diagnosed groups of patients with the commoner functional GI disorders – IBS, dyspepsia, and chronic constipation. The coordinating center for the validation study is UNC, but three other centers will contribute patients.
Validation of the Rome III Questionnaire and Evaluation of Response Frequencies
This subcontract has as its aims: (1) assess the understandability of individual questions in the Rome III Modular Questionnaire, (2) assess test-retest reliability of individual questions and diagnoses based on the Rome III diagnostic criteria, (3) describe the frequency of occurrence of individual symptoms in a large group of healthy controls to provide guidance to the Rome committees in setting thresholds for diagnosis, and (4) assess the sensitivity and specificity of the Rome III diagnoses by comparison to medically diagnosed groups of patients with the commoner functional GI disorders – IBS, dyspepsia, and chronic constipation. The coordinating center for the validation study is UNC, but three other centers will contribute patients.
AGA Outcomes Research Award (Chitkara PI) -- AGA Foundation
The Economic Burden of Irritable Bowel Syndrome and Functional Abdominal Pain from Childhood to Adulthood in a Population Based Birth Cohort
Aim: Retrospectively examine the charges for health services for FAP and associated co-morbid somatic and psychological disorders in a population based birth cohort of 5718 individuals who remained in a single community from childhood to early adulthood (up to 19 years). Regression analysis will be used to determine if early presentation for FAP (<5 years) or having a mother with IBS predicts direct medical costs (outpatient, inpatient clinician visits, procedures, and diagnostic tests).
The Economic Burden of Irritable Bowel Syndrome and Functional Abdominal Pain from Childhood to Adulthood in a Population Based Birth Cohort
Aim: Retrospectively examine the charges for health services for FAP and associated co-morbid somatic and psychological disorders in a population based birth cohort of 5718 individuals who remained in a single community from childhood to early adulthood (up to 19 years). Regression analysis will be used to determine if early presentation for FAP (<5 years) or having a mother with IBS predicts direct medical costs (outpatient, inpatient clinician visits, procedures, and diagnostic tests).
AGA Miles and Shirley Fiterman Joseph B. Kirsner Award in Clinical Research (Drossman)
American Gastroenterological Association
Awarded for distinguished lifetime research in the area of clinical gastroenterology.
American Gastroenterological Association
Awarded for distinguished lifetime research in the area of clinical gastroenterology.
Columbia University Celiac Disease Center (Dorn, Drossman, PIs)
Prediction of Psychosocial Factors and Disease Markers on Health Status in Celiac Disease
Aim: This study will evaluate the predictive effects of severity of celiac disease relative to psychosocial factors on clinical outcome and quality of life.
Prediction of Psychosocial Factors and Disease Markers on Health Status in Celiac Disease
Aim: This study will evaluate the predictive effects of severity of celiac disease relative to psychosocial factors on clinical outcome and quality of life.
Atkins Foundation Award (Drossman, PI, Austin, Co-PI) -- Atkins Foundation
Study of the Effects of a Very Low Carbohydrate Diet on Symptoms of IBS
Aims: This study will evaluate the effects of a very low carbohydrate diet on IBS symptoms. Secondary analysis will include a determination of the mediating effects of postprandial serotonin release on GI symptoms.
Study of the Effects of a Very Low Carbohydrate Diet on Symptoms of IBS
Aims: This study will evaluate the effects of a very low carbohydrate diet on IBS symptoms. Secondary analysis will include a determination of the mediating effects of postprandial serotonin release on GI symptoms.
Rome Foundation (Morgan, PI) -- Rome Foundation for the Functional Gastrointestinal Disorders
Multinational Spanish Translation and Validation of the Rome III Diagnostic Questionnaire in Latin America. Consortium: UNC, Mexico, Nicaragua, Chile
Multinational Spanish Translation and Validation of the Rome III Diagnostic Questionnaire in Latin America. Consortium: UNC, Mexico, Nicaragua, Chile
Rome Foundation (Morgan, PI) -- Rome Foundation for the Functional Gastrointestinal Disorders
The Population-Based Epidemiology of Functional Gastrointestinal Disorders (FGIDs) in Nicaragua
The Population-Based Epidemiology of Functional Gastrointestinal Disorders (FGIDs) in Nicaragua
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